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2 similar compounds to monomer 50184445

Compile data set for download or QSAR
Wt: 303.4
BDBM50076405
Wt: 317.4
BDBM50076409

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076405,50076409   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50076409
PNG
(3-Methyl-2-(4-methyl-piperazin-1-yl)-4-phenyl-quin...)
Show SMILES CN1CCN(CC1)c1nc2ccccc2c(-c2ccccc2)c1C
Show InChI InChI=1S/C21H23N3/c1-16-20(17-8-4-3-5-9-17)18-10-6-7-11-19(18)22-21(16)24-14-12-23(2)13-15-24/h3-11H,12-15H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.40n/an/an/an/an/an/an/an/a



Universit£ di Siena

Curated by ChEMBL


Assay Description
Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue


J Med Chem 42: 1556-75 (1999)


Article DOI: 10.1021/jm981112s
BindingDB Entry DOI: 10.7270/Q2D50NPW
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50076405
PNG
(2-(4-Methyl-piperazin-1-yl)-4-phenyl-quinoline | C...)
Show SMILES CN1CCN(CC1)c1cc(-c2ccccc2)c2ccccc2n1
Show InChI InChI=1S/C20H21N3/c1-22-11-13-23(14-12-22)20-15-18(16-7-3-2-4-8-16)17-9-5-6-10-19(17)21-20/h2-10,15H,11-14H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
5.40n/an/an/an/an/an/an/an/a



Universit£ di Siena

Curated by ChEMBL


Assay Description
Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue


J Med Chem 42: 1556-75 (1999)


Article DOI: 10.1021/jm981112s
BindingDB Entry DOI: 10.7270/Q2D50NPW
More data for this
Ligand-Target Pair