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4 similar compounds to monomer 50084766

Compile data set for download or QSAR
Wt: 355.4
BDBM50084767
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Wt: 325.4
BDBM50084654
Wt: 311.3
BDBM50084656
Wt: 311.3
BDBM50084662
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084767,50084654,50084656,50084662   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084654
PNG
(CHEMBL3427319)
Show SMILES COc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1OC
Show InChI InChI=1S/C19H23N3O2/c1-23-18-9-8-16(14-19(18)24-2)15-20-22-12-10-21(11-13-22)17-6-4-3-5-7-17/h3-9,14-15H,10-13H2,1-2H3/b20-15+
UniProtKB/SwissProt

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Bioorg Med Chem 23: 2904-16 (2015)


Article DOI: 10.1016/j.bmc.2015.02.051
BindingDB Entry DOI: 10.7270/Q2086710
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084767
PNG
(CHEMBL3427329)
Show SMILES COc1cc(\C=N\N2CCN(CC2)c2ccccc2)cc(OC)c1OC
Show InChI InChI=1S/C20H25N3O3/c1-24-18-13-16(14-19(25-2)20(18)26-3)15-21-23-11-9-22(10-12-23)17-7-5-4-6-8-17/h4-8,13-15H,9-12H2,1-3H3/b21-15+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Bioorg Med Chem 23: 2904-16 (2015)


Article DOI: 10.1016/j.bmc.2015.02.051
BindingDB Entry DOI: 10.7270/Q2086710
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084662
PNG
(CHEMBL3427321)
Show SMILES COc1cc(\C=N\N2CCN(CC2)c2ccccc2)ccc1O
Show InChI InChI=1S/C18H21N3O2/c1-23-18-13-15(7-8-17(18)22)14-19-21-11-9-20(10-12-21)16-5-3-2-4-6-16/h2-8,13-14,22H,9-12H2,1H3/b19-14+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Bioorg Med Chem 23: 2904-16 (2015)


Article DOI: 10.1016/j.bmc.2015.02.051
BindingDB Entry DOI: 10.7270/Q2086710
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084656
PNG
(CHEMBL3427320)
Show SMILES COc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1O
Show InChI InChI=1S/C18H21N3O2/c1-23-18-8-7-15(13-17(18)22)14-19-21-11-9-20(10-12-21)16-5-3-2-4-6-16/h2-8,13-14,22H,9-12H2,1H3/b19-14+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Bioorg Med Chem 23: 2904-16 (2015)


Article DOI: 10.1016/j.bmc.2015.02.051
BindingDB Entry DOI: 10.7270/Q2086710
More data for this
Ligand-Target Pair