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10 similar compounds to monomer 50088741

Compile data set for download or QSAR
Wt: 481.6
BDBM50088736
Wt: 479.6
BDBM50088739
Wt: 509.7
BDBM50088743
Wt: 557.7
BDBM50088746
Wt: 509.7
BDBM50088747
Wt: 481.6
BDBM50088716
Wt: 509.7
BDBM50088718
Wt: 467.6
BDBM50088723
Wt: 481.6
BDBM50088730
Wt: 453.6
BDBM50088732

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50088736,50088739,50088743,50088746,50088747,50088716,50088718,50088723,50088730,50088732   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50088747
PNG
(4-[((1R,3S,5S)-8-Phenethyl-8-aza-bicyclo[3.2.1]oct...)
Show SMILES CCCN(CCC)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C34H43N3O/c1-3-22-35(23-4-2)34(38)28-15-17-30(18-16-28)37(29-13-9-6-10-14-29)33-25-31-19-20-32(26-33)36(31)24-21-27-11-7-5-8-12-27/h5-18,31-33H,3-4,19-26H2,1-2H3/t31-,32+,33-
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4n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50088736
PNG
(CHEMBL13327 | N-Methyl-4-[((1R,3S,5S)-8-phenethyl-...)
Show SMILES CCCN(C)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H39N3O/c1-3-21-33(2)32(36)26-14-16-28(17-15-26)35(27-12-8-5-9-13-27)31-23-29-18-19-30(24-31)34(29)22-20-25-10-6-4-7-11-25/h4-17,29-31H,3,18-24H2,1-2H3/t29-,30+,31-
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4n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50088736
PNG
(CHEMBL13327 | N-Methyl-4-[((1R,3S,5S)-8-phenethyl-...)
Show SMILES CCCN(C)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H39N3O/c1-3-21-33(2)32(36)26-14-16-28(17-15-26)35(27-12-8-5-9-13-27)31-23-29-18-19-30(24-31)34(29)22-20-25-10-6-4-7-11-25/h4-17,29-31H,3,18-24H2,1-2H3/t29-,30+,31-
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4n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50088718
PNG
(CHEMBL274167 | N-Butyl-N-ethyl-4-[((1R,3S,5S)-8-ph...)
Show SMILES CCCCN(CC)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C34H43N3O/c1-3-5-23-35(4-2)34(38)28-16-18-30(19-17-28)37(29-14-10-7-11-15-29)33-25-31-20-21-32(26-33)36(31)24-22-27-12-8-6-9-13-27/h6-19,31-33H,3-5,20-26H2,1-2H3/t31-,32+,33-
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5n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50088723
PNG
(CHEMBL13414 | N-Ethyl-N-methyl-4-[((1R,3S,5S)-8-ph...)
Show SMILES CCN(C)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H37N3O/c1-3-32(2)31(35)25-14-16-27(17-15-25)34(26-12-8-5-9-13-26)30-22-28-18-19-29(23-30)33(28)21-20-24-10-6-4-7-11-24/h4-17,28-30H,3,18-23H2,1-2H3/t28-,29+,30-
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5n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50088730
PNG
(CHEMBL275135 | N,N-Diethyl-4-[((1R,3S,5S)-8-phenet...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H39N3O/c1-3-33(4-2)32(36)26-15-17-28(18-16-26)35(27-13-9-6-10-14-27)31-23-29-19-20-30(24-31)34(29)22-21-25-11-7-5-8-12-25/h5-18,29-31H,3-4,19-24H2,1-2H3/t29-,30+,31-
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8n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50088716
PNG
(CHEMBL13169 | N,N-Diethyl-4-[((1R,3R,5S)-8-pheneth...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H39N3O/c1-3-33(4-2)32(36)26-15-17-28(18-16-26)35(27-13-9-6-10-14-27)31-23-29-19-20-30(24-31)34(29)22-21-25-11-7-5-8-12-25/h5-18,29-31H,3-4,19-24H2,1-2H3/t29-,30+,31+
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13n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50088732
PNG
(CHEMBL13309 | N,N-Dimethyl-4-[((1R,3S,5S)-8-phenet...)
Show SMILES CN(C)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H35N3O/c1-31(2)30(34)24-13-15-26(16-14-24)33(25-11-7-4-8-12-25)29-21-27-17-18-28(22-29)32(27)20-19-23-9-5-3-6-10-23/h3-16,27-29H,17-22H2,1-2H3/t27-,28+,29-
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30n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50088743
PNG
(4-[((1R,3R,5S)-8-Phenethyl-8-aza-bicyclo[3.2.1]oct...)
Show SMILES CCCN(CCC)C(=O)c1ccc(cc1)N([C@@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C34H43N3O/c1-3-22-35(23-4-2)34(38)28-15-17-30(18-16-28)37(29-13-9-6-10-14-29)33-25-31-19-20-32(26-33)36(31)24-21-27-11-7-5-8-12-27/h5-18,31-33H,3-4,19-26H2,1-2H3/t31-,32+,33+
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61n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50088716
PNG
(CHEMBL13169 | N,N-Diethyl-4-[((1R,3R,5S)-8-pheneth...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H39N3O/c1-3-33(4-2)32(36)26-15-17-28(18-16-26)35(27-13-9-6-10-14-27)31-23-29-19-20-30(24-31)34(29)22-21-25-11-7-5-8-12-25/h5-18,29-31H,3-4,19-24H2,1-2H3/t29-,30+,31+
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72n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50088739
PNG
(CHEMBL13360 | {4-[((1R,3S,5S)-8-Phenethyl-8-aza-bi...)
Show SMILES O=C(N1CCCC1)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H37N3O/c36-32(33-20-7-8-21-33)26-13-15-28(16-14-26)35(27-11-5-2-6-12-27)31-23-29-17-18-30(24-31)34(29)22-19-25-9-3-1-4-10-25/h1-6,9-16,29-31H,7-8,17-24H2/t29-,30+,31-
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93n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50088723
PNG
(CHEMBL13414 | N-Ethyl-N-methyl-4-[((1R,3S,5S)-8-ph...)
Show SMILES CCN(C)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H37N3O/c1-3-32(2)31(35)25-14-16-27(17-15-25)34(26-12-8-5-9-13-26)30-22-28-18-19-29(23-30)33(28)21-20-24-10-6-4-7-11-24/h4-17,28-30H,3,18-23H2,1-2H3/t28-,29+,30-
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113n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50088730
PNG
(CHEMBL275135 | N,N-Diethyl-4-[((1R,3S,5S)-8-phenet...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H39N3O/c1-3-33(4-2)32(36)26-15-17-28(18-16-26)35(27-13-9-6-10-14-27)31-23-29-19-20-30(24-31)34(29)22-21-25-11-7-5-8-12-25/h5-18,29-31H,3-4,19-24H2,1-2H3/t29-,30+,31-
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124n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50088732
PNG
(CHEMBL13309 | N,N-Dimethyl-4-[((1R,3S,5S)-8-phenet...)
Show SMILES CN(C)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H35N3O/c1-31(2)30(34)24-13-15-26(16-14-24)33(25-11-7-4-8-12-25)29-21-27-17-18-28(22-29)32(27)20-19-23-9-5-3-6-10-23/h3-16,27-29H,17-22H2,1-2H3/t27-,28+,29-
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128n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50088718
PNG
(CHEMBL274167 | N-Butyl-N-ethyl-4-[((1R,3S,5S)-8-ph...)
Show SMILES CCCCN(CC)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C34H43N3O/c1-3-5-23-35(4-2)34(38)28-16-18-30(19-17-28)37(29-14-10-7-11-15-29)33-25-31-20-21-32(26-33)36(31)24-22-27-12-8-6-9-13-27/h6-19,31-33H,3-5,20-26H2,1-2H3/t31-,32+,33-
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244n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50088736
PNG
(CHEMBL13327 | N-Methyl-4-[((1R,3S,5S)-8-phenethyl-...)
Show SMILES CCCN(C)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H39N3O/c1-3-21-33(2)32(36)26-14-16-28(17-15-26)35(27-12-8-5-9-13-27)31-23-29-18-19-30(24-31)34(29)22-20-25-10-6-4-7-11-25/h4-17,29-31H,3,18-24H2,1-2H3/t29-,30+,31-
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293n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50088736
PNG
(CHEMBL13327 | N-Methyl-4-[((1R,3S,5S)-8-phenethyl-...)
Show SMILES CCCN(C)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H39N3O/c1-3-21-33(2)32(36)26-14-16-28(17-15-26)35(27-12-8-5-9-13-27)31-23-29-18-19-30(24-31)34(29)22-20-25-10-6-4-7-11-25/h4-17,29-31H,3,18-24H2,1-2H3/t29-,30+,31-
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308n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50088743
PNG
(4-[((1R,3R,5S)-8-Phenethyl-8-aza-bicyclo[3.2.1]oct...)
Show SMILES CCCN(CCC)C(=O)c1ccc(cc1)N([C@@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C34H43N3O/c1-3-22-35(23-4-2)34(38)28-15-17-30(18-16-28)37(29-13-9-6-10-14-29)33-25-31-19-20-32(26-33)36(31)24-21-27-11-7-5-8-12-27/h5-18,31-33H,3-4,19-26H2,1-2H3/t31-,32+,33+
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370n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50088746
PNG
(4-{[(1S,3R,5R)-8-(2,2-Diphenyl-ethyl)-8-aza-bicycl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1C[C@@H]2CC[C@H](C1)N2CC(c1ccccc1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C38H43N3O/c1-3-39(4-2)38(42)31-20-22-33(23-21-31)41(32-18-12-7-13-19-32)36-26-34-24-25-35(27-36)40(34)28-37(29-14-8-5-9-15-29)30-16-10-6-11-17-30/h5-23,34-37H,3-4,24-28H2,1-2H3/t34-,35+,36+
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550n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50088747
PNG
(4-[((1R,3S,5S)-8-Phenethyl-8-aza-bicyclo[3.2.1]oct...)
Show SMILES CCCN(CCC)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C34H43N3O/c1-3-22-35(23-4-2)34(38)28-15-17-30(18-16-28)37(29-13-9-6-10-14-29)33-25-31-19-20-32(26-33)36(31)24-21-27-11-7-5-8-12-27/h5-18,31-33H,3-4,19-26H2,1-2H3/t31-,32+,33-
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818n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50088739
PNG
(CHEMBL13360 | {4-[((1R,3S,5S)-8-Phenethyl-8-aza-bi...)
Show SMILES O=C(N1CCCC1)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H37N3O/c36-32(33-20-7-8-21-33)26-13-15-28(16-14-26)35(27-11-5-2-6-12-27)31-23-29-17-18-30(24-31)34(29)22-19-25-9-3-1-4-10-25/h1-6,9-16,29-31H,7-8,17-24H2/t29-,30+,31-
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1.34E+3n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50088746
PNG
(4-{[(1S,3R,5R)-8-(2,2-Diphenyl-ethyl)-8-aza-bicycl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1C[C@@H]2CC[C@H](C1)N2CC(c1ccccc1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C38H43N3O/c1-3-39(4-2)38(42)31-20-22-33(23-21-31)41(32-18-12-7-13-19-32)36-26-34-24-25-35(27-36)40(34)28-37(29-14-8-5-9-15-29)30-16-10-6-11-17-30/h5-23,34-37H,3-4,24-28H2,1-2H3/t34-,35+,36+
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1.42E+3n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair