Compounds in cluster

10 similar compounds to monomer 50089197

Wt: 299.3 BDBM50089210	Wt: 299.3 BDBM50089212	Wt: 348.2 BDBM50089214	Wt: 285.3 BDBM50089196	Wt: 335.4 BDBM50089199
Wt: 364.2 BDBM50089200	Wt: 319.4 BDBM50089204	Wt: 271.3 BDBM50089208	Wt: 285.3 BDBM50369525	Wt: 285.3 BDBM50408913

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50089210,50089212,50089214,50089196,50089199,50089200,50089204,50089208,50369525,50408913
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50089196 (3-Benzenesulfonyl-heptanoic acid hydroxyamide \| CH...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against neutral endopeptidase enzyme (NEP).				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli)	BDBM50408913 (CHEMBL2092878) Show SMILES CCCC[C@@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50089199 (3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-13				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50369525 (CHEMBL1788203) Show SMILES CCCC[C@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against angiotensin I converting enzyme (ACE)				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli)	BDBM50089200 (3-(4-Bromo-benzenesulfonyl)-heptanoic acid hydroxy...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccc(Br)cc1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50369525 (CHEMBL1788203) Show SMILES CCCC[C@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against Endothelin-converting enzyme 1				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli)	BDBM50089199 (3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccc2ccccc2c1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50369525 (CHEMBL1788203) Show SMILES CCCC[C@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of human Matrix metalloprotease-12				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50089199 (3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of human Matrix metalloprotease-12				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli)	BDBM50369525 (CHEMBL1788203) Show SMILES CCCC[C@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50089196 (3-Benzenesulfonyl-heptanoic acid hydroxyamide \| CH...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-1				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50369525 (CHEMBL1788203) Show SMILES CCCC[C@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against endopeptidase enzyme (NEP).				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50369525 (CHEMBL1788203) Show SMILES CCCC[C@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-13				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli)	BDBM50089204 (3-(Naphthalene-2-sulfinyl)-heptanoic acid hydroxya...) Show SMILES CCCCC(CC(=O)NO)S(=O)c1ccc2ccccc2c1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50089199 (3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against endopeptidase enzyme (NEP).				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50089196 (3-Benzenesulfonyl-heptanoic acid hydroxyamide \| CH...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against Endothelin-converting enzyme 1				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50089199 (3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against angiotensin I converting enzyme (ACE)				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli)	BDBM50089210 (3-(4-Methoxy-benzenesulfinyl)-heptanoic acid hydro...) Show SMILES CCCCC(CC(=O)NO)S(=O)c1ccc(OC)cc1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli)	BDBM50089208 (3-Benzenesulfonyl-hexanoic acid hydroxyamide \| CHE...) Show SMILES CCCC(CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli)	BDBM50089212 (3-Benzenesulfonyl-octanoic acid hydroxyamide \| CHE...) Show SMILES CCCCCC(CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50089199 (3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccc2ccccc2c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against Endothelin-converting enzyme 1				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli)	BDBM50089214 (3-(4-Bromo-benzenesulfinyl)-heptanoic acid hydroxy...) Show SMILES CCCCC(CC(=O)NO)S(=O)c1ccc(Br)cc1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50089199 (3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-1				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli)	BDBM50089196 (3-Benzenesulfonyl-heptanoic acid hydroxyamide \| CH...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50089196 (3-Benzenesulfonyl-heptanoic acid hydroxyamide \| CH...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-13				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-7 (MMP7) (Homo sapiens (Human))	BDBM50089196 (3-Benzenesulfonyl-heptanoic acid hydroxyamide \| CH...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of matrilysin, Matrix metalloprotease-7				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50089196 (3-Benzenesulfonyl-heptanoic acid hydroxyamide \| CH...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of human Matrix metalloprotease-12				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50089196 (3-Benzenesulfonyl-heptanoic acid hydroxyamide \| CH...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against angiotensin I converting enzyme (ACE)				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-7 (MMP7) (Homo sapiens (Human))	BDBM50089199 (3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...) Show SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of matrilysin, Matrix metalloprotease-7				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50369525 (CHEMBL1788203) Show SMILES CCCC[C@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-1				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50408913 (CHEMBL2092878) Show SMILES CCCC[C@@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against Endothelin-converting enzyme 1				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50408913 (CHEMBL2092878) Show SMILES CCCC[C@@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibitory activity against endopeptidase enzyme (NEP).				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50408913 (CHEMBL2092878) Show SMILES CCCC[C@@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of human Matrix metalloprotease-12				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-7 (MMP7) (Homo sapiens (Human))	BDBM50408913 (CHEMBL2092878) Show SMILES CCCC[C@@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of matrilysin, Matrix metalloprotease-7				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-7 (MMP7) (Homo sapiens (Human))	BDBM50369525 (CHEMBL1788203) Show SMILES CCCC[C@H](CC(=O)NO)S(=O)(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Inhibition of matrilysin, Matrix metalloprotease-7				J Med Chem 43: 2324-31 (2000) Article DOI: 10.1021/jm000018k BindingDB Entry DOI: 10.7270/Q2QF8TJR
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair