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1 similar compounds to monomer 50089755

Compile data set for download or QSAR
Wt: 464.6
BDBM50089745

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089745   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM50089745
PNG
(CHEMBL3577429)
Show SMILES CC1(C)C2CCC1(C)CC2NC(=O)[C@H](NC(=O)N[C@@H](CCCCN)C(O)=O)C1CCCCC1
Show InChI InChI=1S/C25H44N4O4/c1-24(2)17-12-13-25(24,3)15-19(17)27-21(30)20(16-9-5-4-6-10-16)29-23(33)28-18(22(31)32)11-7-8-14-26/h16-20H,4-15,26H2,1-3H3,(H,27,30)(H,31,32)(H2,28,29,33)/t17?,18-,19?,20+,25?/m0/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Institute for Infection Research

Curated by ChEMBL


Assay Description
Inhibition of human activated TAFI incubated for 15 mins by microtiter plate reader based assay


J Med Chem 58: 4839-44 (2015)


Article DOI: 10.1021/jm501840b
BindingDB Entry DOI: 10.7270/Q24B3314
More data for this
Ligand-Target Pair