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8 similar compounds to monomer 50099947

Compile data set for download or QSAR
Wt: 288.3
BDBM50099943
Wt: 274.3
BDBM50326447
Wt: 260.2
BDBM50326466
Wt: 260.2
BDBM50326477
Wt: 324.3
BDBM50347539
Wt: 340.3
BDBM50347540
Wt: 356.3
BDBM50347541
Wt: 292.3
BDBM50428913

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50099943,50326447,50326466,50326477,50347539,50347540,50347541,50428913   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin polymerization-promoting protein


(Bos taurus)
BDBM50099943
PNG
(2,3,4,4'-Tetramethoxy-2'-methyl-biphenyl | CHEMBL3...)
Show SMILES COc1ccc(c(C)c1)-c1ccc(OC)c(OC)c1OC
Show InChI InChI=1S/C17H20O4/c1-11-10-12(18-2)6-7-13(11)14-8-9-15(19-3)17(21-5)16(14)20-4/h6-10H,1-5H3
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.25E+3n/an/an/an/a



Rohm and Haas Company

Curated by ChEMBL


Assay Description
Inhibition of Bos taurus (bovine) brain tubulin polymerization


Bioorg Med Chem Lett 11: 1393-6 (2001)


Article DOI: 10.1016/s0960-894x(01)00246-3
BindingDB Entry DOI: 10.7270/Q20V8C18
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (Common mushroom))
BDBM50326447
PNG
(3',4',5'-Trimethoxy-4-methylbiphenyl-3-ol | CHEMBL...)
Show SMILES COc1cc(cc(OC)c1OC)-c1ccc(C)c(O)c1
Show InChI InChI=1S/C16H18O4/c1-10-5-6-11(7-13(10)17)12-8-14(18-2)16(20-4)15(9-12)19-3/h5-9,17H,1-4H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+6n/an/an/an/an/an/a



Jinan University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase after 30 mins


Bioorg Med Chem 18: 6708-14 (2010)


Article DOI: 10.1016/j.bmc.2010.07.062
BindingDB Entry DOI: 10.7270/Q2JS9QN4
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (Common mushroom))
BDBM50326466
PNG
(3',5'-Dimethoxy-4-methylbiphenyl-3,4'-diol | CHEMB...)
Show SMILES COc1cc(cc(OC)c1O)-c1ccc(C)c(O)c1
Show InChI InChI=1S/C15H16O4/c1-9-4-5-10(6-12(9)16)11-7-13(18-2)15(17)14(8-11)19-3/h4-8,16-17H,1-3H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.00E+4n/an/an/an/an/an/a



Jinan University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase after 30 mins


Bioorg Med Chem 18: 6708-14 (2010)


Article DOI: 10.1016/j.bmc.2010.07.062
BindingDB Entry DOI: 10.7270/Q2JS9QN4
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM50347541
PNG
(CHEMBL465798)
Show SMILES COc1c(O)c(c(O)cc1-c1ccc(O)c(O)c1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C19H16O7/c1-26-19-11(9-2-4-12(20)14(22)6-9)8-16(24)17(18(19)25)10-3-5-13(21)15(23)7-10/h2-8,20-25H,1H3
UniProtKB/SwissProt

GoogleScholar
CHEBI
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of electric eel AChE using acetylthiocholine chloride as substrate after 15 mins by Ellman's method


J Nat Prod 74: 997-1002 (2011)


Article DOI: 10.1021/np100889v
BindingDB Entry DOI: 10.7270/Q21V5FXX
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))
BDBM50428913
PNG
(CHEMBL2331810)
Show SMILES COc1c(O)c(cc(O)c1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C19H16O3/c1-22-19-17(14-10-6-3-7-11-14)16(20)12-15(18(19)21)13-8-4-2-5-9-13/h2-12,20-21H,1H3
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.10E+4n/an/an/an/an/an/a



University of North Carolina at Greensboro

Curated by ChEMBL


Assay Description
Inhibition of human PDE4B2


J Nat Prod 76: 382-7 (2013)


Article DOI: 10.1021/np300749w
BindingDB Entry DOI: 10.7270/Q2TX3GQQ
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM50347539
PNG
(CHEMBL1801782)
Show SMILES COc1c(O)c(c(O)cc1-c1ccc(O)cc1)-c1ccc(O)cc1
Show InChI InChI=1S/C19H16O5/c1-24-19-15(11-2-6-13(20)7-3-11)10-16(22)17(18(19)23)12-4-8-14(21)9-5-12/h2-10,20-23H,1H3
UniProtKB/SwissProt

GoogleScholar
CHEBI
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of electric eel AChE using acetylthiocholine chloride as substrate after 15 mins by Ellman's method


J Nat Prod 74: 997-1002 (2011)


Article DOI: 10.1021/np100889v
BindingDB Entry DOI: 10.7270/Q21V5FXX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM50347540
PNG
(CHEMBL1801783)
Show SMILES COc1c(O)c(c(O)cc1-c1ccc(O)cc1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C19H16O6/c1-25-19-13(10-2-5-12(20)6-3-10)9-16(23)17(18(19)24)11-4-7-14(21)15(22)8-11/h2-9,20-24H,1H3
UniProtKB/SwissProt

GoogleScholar
CHEBI
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of electric eel AChE using acetylthiocholine chloride as substrate after 15 mins by Ellman's method


J Nat Prod 74: 997-1002 (2011)


Article DOI: 10.1021/np100889v
BindingDB Entry DOI: 10.7270/Q21V5FXX
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (Common mushroom))
BDBM50326477
PNG
(3',4',5'-Trimethoxybiphenyl-3-ol | CHEMBL1241350)
Show SMILES COc1cc(cc(OC)c1OC)-c1cccc(O)c1
Show InChI InChI=1S/C15H16O4/c1-17-13-8-11(9-14(18-2)15(13)19-3)10-5-4-6-12(16)7-10/h4-9,16H,1-3H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+6n/an/an/an/an/an/a



Jinan University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase after 30 mins


Bioorg Med Chem 18: 6708-14 (2010)


Article DOI: 10.1016/j.bmc.2010.07.062
BindingDB Entry DOI: 10.7270/Q2JS9QN4
More data for this
Ligand-Target Pair