BindingDB logo
myBDB logout

1 similar compounds to monomer 50101711

Compile data set for download or QSAR
Wt: 498.3
BDBM50101709

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101709   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone chaperone ASF1A


(Homo sapiens)
BDBM50101709
PNG
(CHEMBL3394902)
Show SMILES COc1cccc(c1)C(=O)Nc1ccc(cc1)C(=O)N\N=C\c1cc(Br)c(O)c(OC)c1
Show InChI InChI=1S/C23H20BrN3O5/c1-31-18-5-3-4-16(12-18)22(29)26-17-8-6-15(7-9-17)23(30)27-25-13-14-10-19(24)21(28)20(11-14)32-2/h3-13,28H,1-2H3,(H,26,29)(H,27,30)/b25-13+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



Colorado State University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay


Bioorg Med Chem Lett 25: 963-8 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.067
BindingDB Entry DOI: 10.7270/Q2VM4F0G
More data for this
Ligand-Target Pair