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7 similar compounds to monomer 50101786

Compile data set for download or QSAR
Wt: 294.3
BDBM50101781
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Wt: 280.3
BDBM50101790
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Wt: 349.2
BDBM50101784
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Wt: 336.4
BDBM50101785
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Wt: 314.7
BDBM50101787
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Wt: 348.3
BDBM50101788
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Wt: 314.7
BDBM50101789
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50101781,50101790,50101784,50101785,50101787,50101788,50101789   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50101787
PNG
(4-Chloro-N-(4-phenyl-thiazol-2-yl)-benzamide | CHE...)
Show SMILES Clc1ccc(cc1)C(=O)Nc1nc(cs1)-c1ccccc1
Show InChI InChI=1S/C16H11ClN2OS/c17-13-8-6-12(7-9-13)15(20)19-16-18-14(10-21-16)11-4-2-1-3-5-11/h1-10H,(H,18,19,20)
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PubMed
18n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat cortical membrane


Bioorg Med Chem Lett 11: 2017-9 (2001)


Article DOI: 10.1016/s0960-894x(01)00356-0
BindingDB Entry DOI: 10.7270/Q2HM57QP
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50101781
PNG
(4-Methyl-N-(4-phenyl-thiazol-2-yl)-benzamide | CHE...)
Show SMILES Cc1ccc(cc1)C(=O)Nc1nc(cs1)-c1ccccc1
Show InChI InChI=1S/C17H14N2OS/c1-12-7-9-14(10-8-12)16(20)19-17-18-15(11-21-17)13-5-3-2-4-6-13/h2-11H,1H3,(H,18,19,20)
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36n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat cortical membrane


Bioorg Med Chem Lett 11: 2017-9 (2001)


Article DOI: 10.1016/s0960-894x(01)00356-0
BindingDB Entry DOI: 10.7270/Q2HM57QP
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50101790
PNG
(CHEMBL60334 | N-(4-Phenyl-thiazol-2-yl)-benzamide)
Show SMILES O=C(Nc1nc(cs1)-c1ccccc1)c1ccccc1
Show InChI InChI=1S/C16H12N2OS/c19-15(13-9-5-2-6-10-13)18-16-17-14(11-20-16)12-7-3-1-4-8-12/h1-11H,(H,17,18,19)
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39n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat cortical membrane


Bioorg Med Chem Lett 11: 2017-9 (2001)


Article DOI: 10.1016/s0960-894x(01)00356-0
BindingDB Entry DOI: 10.7270/Q2HM57QP
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50101784
PNG
(3,4-Dichloro-N-(4-phenyl-thiazol-2-yl)-benzamide |...)
Show SMILES Clc1ccc(cc1Cl)C(=O)Nc1nc(cs1)-c1ccccc1
Show InChI InChI=1S/C16H10Cl2N2OS/c17-12-7-6-11(8-13(12)18)15(21)20-16-19-14(9-22-16)10-4-2-1-3-5-10/h1-9H,(H,19,20,21)
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59n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat cortical membrane


Bioorg Med Chem Lett 11: 2017-9 (2001)


Article DOI: 10.1016/s0960-894x(01)00356-0
BindingDB Entry DOI: 10.7270/Q2HM57QP
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50101789
PNG
(3-Chloro-N-(4-phenyl-thiazol-2-yl)-benzamide | CHE...)
Show SMILES Clc1cccc(c1)C(=O)Nc1nc(cs1)-c1ccccc1
Show InChI InChI=1S/C16H11ClN2OS/c17-13-8-4-7-12(9-13)15(20)19-16-18-14(10-21-16)11-5-2-1-3-6-11/h1-10H,(H,18,19,20)
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PubMed
86n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat cortical membrane


Bioorg Med Chem Lett 11: 2017-9 (2001)


Article DOI: 10.1016/s0960-894x(01)00356-0
BindingDB Entry DOI: 10.7270/Q2HM57QP
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50101788
PNG
(CHEMBL59978 | N-(4-Phenyl-thiazol-2-yl)-4-trifluor...)
Show SMILES FC(F)(F)c1ccc(cc1)C(=O)Nc1nc(cs1)-c1ccccc1
Show InChI InChI=1S/C17H11F3N2OS/c18-17(19,20)13-8-6-12(7-9-13)15(23)22-16-21-14(10-24-16)11-4-2-1-3-5-11/h1-10H,(H,21,22,23)
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165n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat cortical membrane


Bioorg Med Chem Lett 11: 2017-9 (2001)


Article DOI: 10.1016/s0960-894x(01)00356-0
BindingDB Entry DOI: 10.7270/Q2HM57QP
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50101785
PNG
(4-tert-Butyl-N-(4-phenyl-thiazol-2-yl)-benzamide |...)
Show SMILES CC(C)(C)c1ccc(cc1)C(=O)Nc1nc(cs1)-c1ccccc1
Show InChI InChI=1S/C20H20N2OS/c1-20(2,3)16-11-9-15(10-12-16)18(23)22-19-21-17(13-24-19)14-7-5-4-6-8-14/h4-13H,1-3H3,(H,21,22,23)
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1.36E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat cortical membrane


Bioorg Med Chem Lett 11: 2017-9 (2001)


Article DOI: 10.1016/s0960-894x(01)00356-0
BindingDB Entry DOI: 10.7270/Q2HM57QP
More data for this
Ligand-Target Pair