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2 similar compounds to monomer 50103506

Compile data set for download or QSAR
Wt: 227.3
BDBM50278114
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Wt: 236.1
BDBM50103490

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278114,50103490   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor


(RAT)
BDBM50278114
PNG
(CHEMBL513012 | N-cyclohexylquinazolin-4-amine)
Show SMILES C1CCC(CC1)Nc1ncnc2ccccc12
Show InChI InChI=1S/C14H17N3/c1-2-6-11(7-3-1)17-14-12-8-4-5-9-13(12)15-10-16-14/h4-5,8-11H,1-3,6-7H2,(H,15,16,17)
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
27n/an/an/an/an/an/an/an/a



Medical Research Council Technology

Curated by ChEMBL


Assay Description
Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...


Bioorg Med Chem Lett 19: 2190-4 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.106
BindingDB Entry DOI: 10.7270/Q2057FSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM50103490
PNG
(CHEMBL3398295)
Show SMILES COc1cc(O)c2c(c1)oc(cc2=O)C(O)=O
Show InChI InChI=1S/C11H8O6/c1-16-5-2-6(12)10-7(13)4-9(11(14)15)17-8(10)3-5/h2-4,12H,1H3,(H,14,15)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method


Bioorg Med Chem 23: 911-23 (2015)


Article DOI: 10.1016/j.bmc.2015.01.042
BindingDB Entry DOI: 10.7270/Q2BG2QS9
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50103490
PNG
(CHEMBL3398295)
Show SMILES COc1cc(O)c2c(c1)oc(cc2=O)C(O)=O
Show InChI InChI=1S/C11H8O6/c1-16-5-2-6(12)10-7(13)4-9(11(14)15)17-8(10)3-5/h2-4,12H,1H3,(H,14,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of AChE from rat cortex homogenate using acetylthiocholine iodide as substrate after 15 mins by Ellman method


Bioorg Med Chem 23: 911-23 (2015)


Article DOI: 10.1016/j.bmc.2015.01.042
BindingDB Entry DOI: 10.7270/Q2BG2QS9
More data for this
Ligand-Target Pair