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5 similar compounds to monomer 50111572

Wt: 353.4
BDBM50111556
Wt: 355.3
BDBM50111562
Wt: 356.3
BDBM50111578

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50111556,50111562,50111578   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin


(Bos taurus)
BDBM50111556
PNG
(CHEMBL297236 | Dimethyl-{4-[3-(3,4,5-trimethoxy-ph...)
Show SMILES COc1cc(cc(OC)c1OC)-n1cncc1-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C20H23N3O3/c1-22(2)15-8-6-14(7-9-15)17-12-21-13-23(17)16-10-18(24-3)20(26-5)19(11-16)25-4/h6-13H,1-5H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration needed to inhibit tubulin polymerization by 50%


Citation and Details
More data for this
Ligand-Target Pair
Tubulin


(Bos taurus)
BDBM50111562
PNG
(2-Methoxy-5-[3-(3,4,5-trimethoxy-phenyl)-3H-imidaz...)
Show SMILES COc1ccc(cc1N)-c1cncn1-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C19H21N3O4/c1-23-16-6-5-12(7-14(16)20)15-10-21-11-22(15)13-8-17(24-2)19(26-4)18(9-13)25-3/h5-11H,20H2,1-4H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 7.70E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration needed to inhibit tubulin polymerization by 50%


Citation and Details
More data for this
Ligand-Target Pair
Tubulin


(Bos taurus)
BDBM50111578
PNG
(2-Methoxy-5-[3-(3,4,5-trimethoxy-phenyl)-3H-imidaz...)
Show SMILES COc1ccc(cc1O)-c1cncn1-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C19H20N2O5/c1-23-16-6-5-12(7-15(16)22)14-10-20-11-21(14)13-8-17(24-2)19(26-4)18(9-13)25-3/h5-11,22H,1-4H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 7.60E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration needed to inhibit tubulin polymerization by 50%


Citation and Details
More data for this
Ligand-Target Pair