BindingDB logo
myBDB logout

2 similar compounds to monomer 50111573

Wt: 369.4
BDBM50111559
Wt: 355.3
BDBM50111568

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50111559,50111568   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin


(Bos taurus)
BDBM50111568
PNG
(2-Methoxy-5-[5-(3,4,5-trimethoxy-phenyl)-3H-imidaz...)
Show SMILES COc1ccc(cc1N)-c1nc[nH]c1-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C19H21N3O4/c1-23-14-6-5-11(7-13(14)20)17-18(22-10-21-17)12-8-15(24-2)19(26-4)16(9-12)25-3/h5-10H,20H2,1-4H3,(H,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 680n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration needed to inhibit tubulin polymerization by 50%


Citation and Details
More data for this
Ligand-Target Pair
Tubulin


(Bos taurus)
BDBM50111559
PNG
(2-Methoxy-5-[3-methyl-5-(3,4,5-trimethoxy-phenyl)-...)
Show SMILES COc1ccc(cc1N)-c1c(ncn1C)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C20H23N3O4/c1-23-11-22-18(19(23)12-6-7-15(24-2)14(21)8-12)13-9-16(25-3)20(27-5)17(10-13)26-4/h6-11H,21H2,1-5H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 3.10E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration needed to inhibit tubulin polymerization by 50%


Citation and Details
More data for this
Ligand-Target Pair