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1 similar compounds to monomer 50116675

Compile data set for download or QSAR
Wt: 138.2
BDBM50116667

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116667   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric Oxide Synthase, inducible


(Mus musculus (mouse))
BDBM50116667
PNG
(4,5,5-Trimethyl-5,6-dihydro-1H-pyridin-(2Z)-yliden...)
Show SMILES CC1=CC(N)=NCC1(C)C
Show InChI InChI=1S/C8H14N2/c1-6-4-7(9)10-5-8(6,2)3/h4H,5H2,1-3H3,(H2,9,10)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
The concentration required for inhibition of Inducible nitric oxide synthase in mouse


Bioorg Med Chem Lett 12: 2291-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00455-9
BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116667
PNG
(4,5,5-Trimethyl-5,6-dihydro-1H-pyridin-(2Z)-yliden...)
Show SMILES CC1=CC(N)=NCC1(C)C
Show InChI InChI=1S/C8H14N2/c1-6-4-7(9)10-5-8(6,2)3/h4H,5H2,1-3H3,(H2,9,10)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00455-9
BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116667
PNG
(4,5,5-Trimethyl-5,6-dihydro-1H-pyridin-(2Z)-yliden...)
Show SMILES CC1=CC(N)=NCC1(C)C
Show InChI InChI=1S/C8H14N2/c1-6-4-7(9)10-5-8(6,2)3/h4H,5H2,1-3H3,(H2,9,10)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit human Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00455-9
BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair