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1 similar compounds to monomer 50124147

Compile data set for download or QSAR
Wt: 283.3
BDBM50124151

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124151   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adrenergic receptor alpha-1


(Homo sapiens (Human))
BDBM50124151
PNG
(2-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)-6-methyl-py...)
Show SMILES Cc1cc(NCCO)cc(n1)N1CCc2ccccc2C1
Show InChI InChI=1S/C17H21N3O/c1-13-10-16(18-7-9-21)11-17(19-13)20-8-6-14-4-2-3-5-15(14)12-20/h2-5,10-11,21H,6-9,12H2,1H3,(H,18,19)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.30E+3n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from Alpha-1 adrenergic receptor


Bioorg Med Chem Lett 13: 829-32 (2003)


Article DOI: 10.1016/s0960-894x(03)00007-6
BindingDB Entry DOI: 10.7270/Q25M652M
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50124151
PNG
(2-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)-6-methyl-py...)
Show SMILES Cc1cc(NCCO)cc(n1)N1CCc2ccccc2C1
Show InChI InChI=1S/C17H21N3O/c1-13-10-16(18-7-9-21)11-17(19-13)20-8-6-14-4-2-3-5-15(14)12-20/h2-5,10-11,21H,6-9,12H2,1H3,(H,18,19)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.80E+3n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]-pirenzepine from M1 receptor


Bioorg Med Chem Lett 13: 829-32 (2003)


Article DOI: 10.1016/s0960-894x(03)00007-6
BindingDB Entry DOI: 10.7270/Q25M652M
More data for this
Ligand-Target Pair