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1 similar compounds to monomer 50128242

Compile data set for download or QSAR
Wt: 268.3
BDBM50128240

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50128240   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50128240
PNG
(CHEMBL308924 | endo-8-Dimethylaminomethyl-4-hydrox...)
Show SMILES CCOC(=O)C1CN2CC(CCC2CN(C)C)C1=O
Show InChI InChI=1/C14H24N2O3/c1-4-19-14(18)12-9-16-7-10(13(12)17)5-6-11(16)8-15(2)3/h10-12H,4-9H2,1-3H3
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UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.70E+4n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined towards human Muscarinic acetylcholine receptor M3 using [3H]-QNB radioligand


J Med Chem 46: 2216-26 (2003)


Article DOI: 10.1021/jm020572p
BindingDB Entry DOI: 10.7270/Q2GB23DS
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50128240
PNG
(CHEMBL308924 | endo-8-Dimethylaminomethyl-4-hydrox...)
Show SMILES CCOC(=O)C1CN2CC(CCC2CN(C)C)C1=O
Show InChI InChI=1/C14H24N2O3/c1-4-19-14(18)12-9-16-7-10(13(12)17)5-6-11(16)8-15(2)3/h10-12H,4-9H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
8.60E+4n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined towards human Muscarinic acetylcholine receptor M2 using [3H]-QNB radioligand


J Med Chem 46: 2216-26 (2003)


Article DOI: 10.1021/jm020572p
BindingDB Entry DOI: 10.7270/Q2GB23DS
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M4


(Homo sapiens (Human))
BDBM50128240
PNG
(CHEMBL308924 | endo-8-Dimethylaminomethyl-4-hydrox...)
Show SMILES CCOC(=O)C1CN2CC(CCC2CN(C)C)C1=O
Show InChI InChI=1/C14H24N2O3/c1-4-19-14(18)12-9-16-7-10(13(12)17)5-6-11(16)8-15(2)3/h10-12H,4-9H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined towards human Muscarinic acetylcholine receptor M4 using [3H]-QNB radioligand


J Med Chem 46: 2216-26 (2003)


Article DOI: 10.1021/jm020572p
BindingDB Entry DOI: 10.7270/Q2GB23DS
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50128240
PNG
(CHEMBL308924 | endo-8-Dimethylaminomethyl-4-hydrox...)
Show SMILES CCOC(=O)C1CN2CC(CCC2CN(C)C)C1=O
Show InChI InChI=1/C14H24N2O3/c1-4-19-14(18)12-9-16-7-10(13(12)17)5-6-11(16)8-15(2)3/h10-12H,4-9H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined towards human Muscarinic acetylcholine receptor M3 using [3H]-QNB radioligand


J Med Chem 46: 2216-26 (2003)


Article DOI: 10.1021/jm020572p
BindingDB Entry DOI: 10.7270/Q2GB23DS
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M5 chimeric protein


(Homo sapiens (Human))
BDBM50128240
PNG
(CHEMBL308924 | endo-8-Dimethylaminomethyl-4-hydrox...)
Show SMILES CCOC(=O)C1CN2CC(CCC2CN(C)C)C1=O
Show InChI InChI=1/C14H24N2O3/c1-4-19-14(18)12-9-16-7-10(13(12)17)5-6-11(16)8-15(2)3/h10-12H,4-9H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined towards human Muscarinic acetylcholine receptor M5 using [3H]-QNB radioligand


J Med Chem 46: 2216-26 (2003)


Article DOI: 10.1021/jm020572p
BindingDB Entry DOI: 10.7270/Q2GB23DS
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50128240
PNG
(CHEMBL308924 | endo-8-Dimethylaminomethyl-4-hydrox...)
Show SMILES CCOC(=O)C1CN2CC(CCC2CN(C)C)C1=O
Show InChI InChI=1/C14H24N2O3/c1-4-19-14(18)12-9-16-7-10(13(12)17)5-6-11(16)8-15(2)3/h10-12H,4-9H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined towards human Muscarinic acetylcholine receptor M2 using [3H]-QNB radioligand


J Med Chem 46: 2216-26 (2003)


Article DOI: 10.1021/jm020572p
BindingDB Entry DOI: 10.7270/Q2GB23DS
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50128240
PNG
(CHEMBL308924 | endo-8-Dimethylaminomethyl-4-hydrox...)
Show SMILES CCOC(=O)C1CN2CC(CCC2CN(C)C)C1=O
Show InChI InChI=1/C14H24N2O3/c1-4-19-14(18)12-9-16-7-10(13(12)17)5-6-11(16)8-15(2)3/h10-12H,4-9H2,1-3H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined towards human Muscarinic acetylcholine receptor M1 using [3H]-QNB radioligand


J Med Chem 46: 2216-26 (2003)


Article DOI: 10.1021/jm020572p
BindingDB Entry DOI: 10.7270/Q2GB23DS
More data for this
Ligand-Target Pair