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6 similar compounds to monomer 50129075

Compile data set for download or QSAR
Wt: 391.4
BDBM50129070
Wt: 403.4
BDBM50129071
Wt: 389.4
BDBM50129074
Wt: 389.4
BDBM50129076
Wt: 389.4
BDBM50129077
Wt: 375.3
BDBM50129078

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50129070,50129071,50129074,50129076,50129077,50129078   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin K


(Homo sapiens (Human))
BDBM50129070
PNG
(Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamin...)
Show SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H]1[C@@H](NC1=O)OC(C)=O
Show InChI InChI=1S/C19H25N3O6/c1-11(2)9-14(20-19(26)27-10-13-7-5-4-6-8-13)16(24)21-15-17(25)22-18(15)28-12(3)23/h4-8,11,14-15,18H,9-10H2,1-3H3,(H,20,26)(H,21,24)(H,22,25)/t14-,15+,18-/m0/s1
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2.20n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin K


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))
BDBM50129071
PNG
(Acetic acid (1S,2S,4R)-3-[(2-benzyloxycarbonylamin...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)[C@@H]1CCCC[C@@H]1NC(=O)OCc1ccccc1
Show InChI InChI=1S/C20H25N3O6/c1-12(24)29-19-16(18(26)23-19)22-17(25)14-9-5-6-10-15(14)21-20(27)28-11-13-7-3-2-4-8-13/h2-4,7-8,14-16,19H,5-6,9-11H2,1H3,(H,21,27)(H,22,25)(H,23,26)/t14-,15+,16-,19+/m1/s1
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8.80n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin K


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))
BDBM50129070
PNG
(Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamin...)
Show SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H]1[C@@H](NC1=O)OC(C)=O
Show InChI InChI=1S/C19H25N3O6/c1-11(2)9-14(20-19(26)27-10-13-7-5-4-6-8-13)16(24)21-15-17(25)22-18(15)28-12(3)23/h4-8,11,14-15,18H,9-10H2,1-3H3,(H,20,26)(H,21,24)(H,22,25)/t14-,15+,18-/m0/s1
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9.20n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin S


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin L1


(Homo sapiens (Human))
BDBM50129070
PNG
(Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamin...)
Show SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H]1[C@@H](NC1=O)OC(C)=O
Show InChI InChI=1S/C19H25N3O6/c1-11(2)9-14(20-19(26)27-10-13-7-5-4-6-8-13)16(24)21-15-17(25)22-18(15)28-12(3)23/h4-8,11,14-15,18H,9-10H2,1-3H3,(H,20,26)(H,21,24)(H,22,25)/t14-,15+,18-/m0/s1
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88n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin L


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))
BDBM50129071
PNG
(Acetic acid (1S,2S,4R)-3-[(2-benzyloxycarbonylamin...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)[C@@H]1CCCC[C@@H]1NC(=O)OCc1ccccc1
Show InChI InChI=1S/C20H25N3O6/c1-12(24)29-19-16(18(26)23-19)22-17(25)14-9-5-6-10-15(14)21-20(27)28-11-13-7-3-2-4-8-13/h2-4,7-8,14-16,19H,5-6,9-11H2,1H3,(H,21,27)(H,22,25)(H,23,26)/t14-,15+,16-,19+/m1/s1
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130n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin S


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))
BDBM50129077
PNG
(Acetic acid (2S,3S)-3-[(1-benzyloxycarbonylamino-c...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1(CCCC1)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C19H23N3O6/c1-12(23)28-16-14(15(24)21-16)20-17(25)19(9-5-6-10-19)22-18(26)27-11-13-7-3-2-4-8-13/h2-4,7-8,14,16H,5-6,9-11H2,1H3,(H,20,25)(H,21,24)(H,22,26)/t14-,16+/m1/s1
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160n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin K


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))
BDBM50129074
PNG
(2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1CCCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C19H23N3O6/c1-12(23)28-18-15(17(25)21-18)20-16(24)14-9-5-6-10-22(14)19(26)27-11-13-7-3-2-4-8-13/h2-4,7-8,14-15,18H,5-6,9-11H2,1H3,(H,20,24)(H,21,25)/t14?,15-,18+/m1/s1
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200n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin K


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))
BDBM50129078
PNG
(2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C18H21N3O6/c1-11(22)27-17-14(16(24)20-17)19-15(23)13-8-5-9-21(13)18(25)26-10-12-6-3-2-4-7-12/h2-4,6-7,13-14,17H,5,8-10H2,1H3,(H,19,23)(H,20,24)/t13?,14-,17+/m1/s1
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950n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin K


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin (B and K)


(Homo sapiens (Human))
BDBM50129071
PNG
(Acetic acid (1S,2S,4R)-3-[(2-benzyloxycarbonylamin...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)[C@@H]1CCCC[C@@H]1NC(=O)OCc1ccccc1
Show InChI InChI=1S/C20H25N3O6/c1-12(24)29-19-16(18(26)23-19)22-17(25)14-9-5-6-10-15(14)21-20(27)28-11-13-7-3-2-4-8-13/h2-4,7-8,14-16,19H,5-6,9-11H2,1H3,(H,21,27)(H,22,25)(H,23,26)/t14-,15+,16-,19+/m1/s1
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1.60E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin B


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin (B and K)


(Homo sapiens (Human))
BDBM50129070
PNG
(Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamin...)
Show SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H]1[C@@H](NC1=O)OC(C)=O
Show InChI InChI=1S/C19H25N3O6/c1-11(2)9-14(20-19(26)27-10-13-7-5-4-6-8-13)16(24)21-15-17(25)22-18(15)28-12(3)23/h4-8,11,14-15,18H,9-10H2,1-3H3,(H,20,26)(H,21,24)(H,22,25)/t14-,15+,18-/m0/s1
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2.10E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin B


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))
BDBM50129076
PNG
(Acetic acid (2S,3S)-3-{[(R)-2-((S)-benzyloxycarbon...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)[C@@H]1CCC[C@@H]1NC(=O)OCc1ccccc1
Show InChI InChI=1S/C19H23N3O6/c1-11(23)28-18-15(17(25)22-18)21-16(24)13-8-5-9-14(13)20-19(26)27-10-12-6-3-2-4-7-12/h2-4,6-7,13-15,18H,5,8-10H2,1H3,(H,20,26)(H,21,24)(H,22,25)/t13-,14+,15-,18+/m1/s1
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2.10E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin K


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin L1


(Homo sapiens (Human))
BDBM50129071
PNG
(Acetic acid (1S,2S,4R)-3-[(2-benzyloxycarbonylamin...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)[C@@H]1CCCC[C@@H]1NC(=O)OCc1ccccc1
Show InChI InChI=1S/C20H25N3O6/c1-12(24)29-19-16(18(26)23-19)22-17(25)14-9-5-6-10-15(14)21-20(27)28-11-13-7-3-2-4-8-13/h2-4,7-8,14-16,19H,5-6,9-11H2,1H3,(H,21,27)(H,22,25)(H,23,26)/t14-,15+,16-,19+/m1/s1
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3.70E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin L


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin (B and K)


(Homo sapiens (Human))
BDBM50129077
PNG
(Acetic acid (2S,3S)-3-[(1-benzyloxycarbonylamino-c...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1(CCCC1)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C19H23N3O6/c1-12(23)28-16-14(15(24)21-16)20-17(25)19(9-5-6-10-19)22-18(26)27-11-13-7-3-2-4-8-13/h2-4,7-8,14,16H,5-6,9-11H2,1H3,(H,20,25)(H,21,24)(H,22,26)/t14-,16+/m1/s1
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7.70E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin B


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))
BDBM50129076
PNG
(Acetic acid (2S,3S)-3-{[(R)-2-((S)-benzyloxycarbon...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)[C@@H]1CCC[C@@H]1NC(=O)OCc1ccccc1
Show InChI InChI=1S/C19H23N3O6/c1-11(23)28-18-15(17(25)22-18)21-16(24)13-8-5-9-14(13)20-19(26)27-10-12-6-3-2-4-7-12/h2-4,6-7,13-15,18H,5,8-10H2,1H3,(H,20,26)(H,21,24)(H,22,25)/t13-,14+,15-,18+/m1/s1
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1.10E+4n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin S


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))
BDBM50129074
PNG
(2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1CCCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C19H23N3O6/c1-12(23)28-18-15(17(25)21-18)20-16(24)14-9-5-6-10-22(14)19(26)27-11-13-7-3-2-4-8-13/h2-4,7-8,14-15,18H,5-6,9-11H2,1H3,(H,20,24)(H,21,25)/t14?,15-,18+/m1/s1
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2.00E+4n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin S


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))
BDBM50129077
PNG
(Acetic acid (2S,3S)-3-[(1-benzyloxycarbonylamino-c...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1(CCCC1)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C19H23N3O6/c1-12(23)28-16-14(15(24)21-16)20-17(25)19(9-5-6-10-19)22-18(26)27-11-13-7-3-2-4-8-13/h2-4,7-8,14,16H,5-6,9-11H2,1H3,(H,20,25)(H,21,24)(H,22,26)/t14-,16+/m1/s1
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2.80E+4n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin S


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin (B and K)


(Homo sapiens (Human))
BDBM50129076
PNG
(Acetic acid (2S,3S)-3-{[(R)-2-((S)-benzyloxycarbon...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)[C@@H]1CCC[C@@H]1NC(=O)OCc1ccccc1
Show InChI InChI=1S/C19H23N3O6/c1-11(23)28-18-15(17(25)22-18)21-16(24)13-8-5-9-14(13)20-19(26)27-10-12-6-3-2-4-7-12/h2-4,6-7,13-15,18H,5,8-10H2,1H3,(H,20,26)(H,21,24)(H,22,25)/t13-,14+,15-,18+/m1/s1
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5.20E+4n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin B


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin (B and K)


(Homo sapiens (Human))
BDBM50129074
PNG
(2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1CCCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C19H23N3O6/c1-12(23)28-18-15(17(25)21-18)20-16(24)14-9-5-6-10-22(14)19(26)27-11-13-7-3-2-4-8-13/h2-4,7-8,14-15,18H,5-6,9-11H2,1H3,(H,20,24)(H,21,25)/t14?,15-,18+/m1/s1
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6.50E+4n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin B


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin (B and K)


(Homo sapiens (Human))
BDBM50129078
PNG
(2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C18H21N3O6/c1-11(22)27-17-14(16(24)20-17)19-15(23)13-8-5-9-21(13)18(25)26-10-12-6-3-2-4-7-12/h2-4,6-7,13-14,17H,5,8-10H2,1H3,(H,19,23)(H,20,24)/t13?,14-,17+/m1/s1
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1.20E+5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin B


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin L1


(Homo sapiens (Human))
BDBM50129077
PNG
(Acetic acid (2S,3S)-3-[(1-benzyloxycarbonylamino-c...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1(CCCC1)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C19H23N3O6/c1-12(23)28-16-14(15(24)21-16)20-17(25)19(9-5-6-10-19)22-18(26)27-11-13-7-3-2-4-8-13/h2-4,7-8,14,16H,5-6,9-11H2,1H3,(H,20,25)(H,21,24)(H,22,26)/t14-,16+/m1/s1
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1.40E+5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin L


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin L1


(Homo sapiens (Human))
BDBM50129078
PNG
(2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C18H21N3O6/c1-11(22)27-17-14(16(24)20-17)19-15(23)13-8-5-9-21(13)18(25)26-10-12-6-3-2-4-7-12/h2-4,6-7,13-14,17H,5,8-10H2,1H3,(H,19,23)(H,20,24)/t13?,14-,17+/m1/s1
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>1.50E+5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin L


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin L1


(Homo sapiens (Human))
BDBM50129076
PNG
(Acetic acid (2S,3S)-3-{[(R)-2-((S)-benzyloxycarbon...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)[C@@H]1CCC[C@@H]1NC(=O)OCc1ccccc1
Show InChI InChI=1S/C19H23N3O6/c1-11(23)28-18-15(17(25)22-18)21-16(24)13-8-5-9-14(13)20-19(26)27-10-12-6-3-2-4-7-12/h2-4,6-7,13-15,18H,5,8-10H2,1H3,(H,20,26)(H,21,24)(H,22,25)/t13-,14+,15-,18+/m1/s1
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>1.50E+5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin L


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))
BDBM50129078
PNG
(2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C18H21N3O6/c1-11(22)27-17-14(16(24)20-17)19-15(23)13-8-5-9-21(13)18(25)26-10-12-6-3-2-4-7-12/h2-4,6-7,13-14,17H,5,8-10H2,1H3,(H,19,23)(H,20,24)/t13?,14-,17+/m1/s1
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>1.50E+5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin S


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair
Cathepsin L1


(Homo sapiens (Human))
BDBM50129074
PNG
(2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)...)
Show SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1CCCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C19H23N3O6/c1-12(23)28-18-15(17(25)21-18)20-16(24)14-9-5-6-10-22(14)19(26)27-11-13-7-3-2-4-8-13/h2-4,7-8,14-15,18H,5-6,9-11H2,1H3,(H,20,24)(H,21,25)/t14?,15-,18+/m1/s1
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>1.50E+5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was measured against Cathepsin L


Bioorg Med Chem Lett 13: 2051-3 (2003)


Article DOI: 10.1016/s0960-894x(03)00304-4
BindingDB Entry DOI: 10.7270/Q2BG2NDJ
More data for this
Ligand-Target Pair