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2 similar compounds to monomer 17847

Wt: 320.3
BDBM50129643
Wt: 320.3
BDBM50160045

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50129643,50160045   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine Aminopeptidase (MAP)


(Escherichia coli (strain K12))
BDBM50160045
PNG
(CHEMBL179906 | [6-(Thiazol-2-ylcarbamoyl)-pyridin-...)
Show SMILES CC(C)(C)OC(=O)Nc1ccc(nc1)C(=O)Nc1nccs1
Show InChI InChI=1S/C14H16N4O3S/c1-14(2,3)21-13(20)17-9-4-5-10(16-8-9)11(19)18-12-15-6-7-22-12/h4-8H,1-3H3,(H,17,20)(H,15,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.28E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory concentration against Escherichia coli methionine aminopeptidase 1


Bioorg Med Chem Lett 15: 635-8 (2005)

More data for this
Ligand-Target Pair
Methionine Aminopeptidase (MAP)


(Escherichia coli (strain K12))
BDBM50129643
PNG
(CHEMBL89523 | [2-(Thiazol-2-ylcarbamoyl)-pyridin-3...)
Show SMILES CC(C)COC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H16N4O3S/c1-9(2)8-21-14(20)17-10-4-3-5-15-11(10)12(19)18-13-16-6-7-22-13/h3-7,9H,8H2,1-2H3,(H,17,20)(H,16,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.92E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli


J Med Chem 46: 2631-40 (2003)

More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)
BDBM50129643
PNG
(CHEMBL89523 | [2-(Thiazol-2-ylcarbamoyl)-pyridin-3...)
Show SMILES CC(C)COC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H16N4O3S/c1-9(2)8-21-14(20)17-10-4-3-5-15-11(10)12(19)18-13-16-6-7-22-13/h3-7,9H,8H2,1-2H3,(H,17,20)(H,16,18,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.37E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae


J Med Chem 46: 2631-40 (2003)

More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)
BDBM50160045
PNG
(CHEMBL179906 | [6-(Thiazol-2-ylcarbamoyl)-pyridin-...)
Show SMILES CC(C)(C)OC(=O)Nc1ccc(nc1)C(=O)Nc1nccs1
Show InChI InChI=1S/C14H16N4O3S/c1-14(2,3)21-13(20)17-9-4-5-10(16-8-9)11(19)18-12-15-6-7-22-12/h4-8H,1-3H3,(H,17,20)(H,15,18,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.29E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory concentration against Saccharomyces cerevisiae methionine aminopeptidase 1


Bioorg Med Chem Lett 15: 635-8 (2005)

More data for this
Ligand-Target Pair