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18 similar compounds to monomer 50149107

Compile data set for download or QSAR
Wt: 302.3
BDBM50145226
Wt: 370.3
BDBM50145229
Wt: 332.3
BDBM50145231
Wt: 366.8
BDBM50149103
Wt: 371.2
BDBM50149104
Wt: 320.3
BDBM50149108
Wt: 336.8
BDBM50149111
Wt: 346.4
BDBM50149113
Wt: 336.8
BDBM50149114
Wt: 336.8
BDBM50149115
Wt: 318.3
BDBM50149116
Wt: 316.3
BDBM50149119
Wt: 381.2
BDBM50149122
Wt: 336.8
BDBM50149123
Wt: 371.2
BDBM50149125
Displayed 1 to 15 (of 18 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 51 hits for monomerid = 50145226,50145229,50145231,50149103,50149104,50149108,50149111,50149113,50149114,50149115,50149116,50149119,50149122,50149123,50149125   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149103
PNG
(5-Butyl-9-chloro-2-(4-methoxy-phenyl)-[1,2,4]triaz...)
Show SMILES CCCCc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccc(OC)cc1
Show InChI InChI=1S/C20H19ClN4O/c1-3-4-5-18-22-17-11-8-14(21)12-16(17)20-23-19(24-25(18)20)13-6-9-15(26-2)10-7-13/h6-12H,3-5H2,1-2H3
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n/an/a 33n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50149122
PNG
(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(Br)cc1
Show InChI InChI=1S/C19H17BrN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells after 60 mins by gamma counter


J Med Chem 55: 5676-703 (2012)


Article DOI: 10.1021/jm300087j
BindingDB Entry DOI: 10.7270/Q25H7HDK
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50149104
PNG
(5-Butyl-9-chloro-2-(4-chloro-phenyl)-[1,2,4]triazo...)
Show SMILES CCCCc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H16Cl2N4/c1-2-3-4-17-22-16-10-9-14(21)11-15(16)19-23-18(24-25(17)19)12-5-7-13(20)8-6-12/h5-11H,2-4H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-DPCPX binding at human adenosine A1 receptor expressed in CHO cells.


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149108
PNG
(5-Butyl-2-(4-fluoro-phenyl)-[1,2,4]triazolo[1,5-c]...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(F)cc1
Show InChI InChI=1S/C19H17FN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a 28n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149111
PNG
(5-Butyl-2-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-c]...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a 26n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149113
PNG
(5-Butyl-2-(4-ethoxy-phenyl)-[1,2,4]triazolo[1,5-c]...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(OCC)cc1
Show InChI InChI=1S/C21H22N4O/c1-3-5-10-19-22-18-9-7-6-8-17(18)21-23-20(24-25(19)21)15-11-13-16(14-12-15)26-4-2/h6-9,11-14H,3-5,10H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149114
PNG
(5-Butyl-10-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]q...)
Show SMILES CCCCc1nc2cccc(Cl)c2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-12-16-21-15-11-7-10-14(20)17(15)19-22-18(23-24(16)19)13-8-5-4-6-9-13/h4-11H,2-3,12H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149111
PNG
(5-Butyl-2-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-c]...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50149115
PNG
(5-Butyl-8-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]qu...)
Show SMILES CCCCc1nc2cc(Cl)ccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-9-17-21-16-12-14(20)10-11-15(16)19-22-18(23-24(17)19)13-7-5-4-6-8-13/h4-8,10-12H,2-3,9H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-DPCPX binding at human adenosine A2B receptor expressed in HEK-293 cells.


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149115
PNG
(5-Butyl-8-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]qu...)
Show SMILES CCCCc1nc2cc(Cl)ccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-9-17-21-16-12-14(20)10-11-15(16)19-22-18(23-24(17)19)13-7-5-4-6-8-13/h4-8,10-12H,2-3,9H2,1H3
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n/an/a 48n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149116
PNG
(4-(5-Butyl-[1,2,4]triazolo[1,5-c]quinazolin-2-yl)-...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(O)cc1
Show InChI InChI=1S/C19H18N4O/c1-2-3-8-17-20-16-7-5-4-6-15(16)19-21-18(22-23(17)19)13-9-11-14(24)12-10-13/h4-7,9-12,24H,2-3,8H2,1H3
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n/an/a 10n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50145229
PNG
(5-Butyl-2-(4-trifluoromethyl-phenyl)-[1,2,4]triazo...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H17F3N4/c1-2-3-8-17-24-16-7-5-4-6-15(16)19-25-18(26-27(17)19)13-9-11-14(12-10-13)20(21,22)23/h4-7,9-12H,2-3,8H2,1H3
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n/an/a 490n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149119
PNG
(5-Butyl-8-methyl-2-phenyl-[1,2,4]triazolo[1,5-c]qu...)
Show SMILES CCCCc1nc2cc(C)ccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C20H20N4/c1-3-4-10-18-21-17-13-14(2)11-12-16(17)20-22-19(23-24(18)20)15-8-6-5-7-9-15/h5-9,11-13H,3-4,10H2,1-2H3
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n/an/a 110n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149122
PNG
(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(Br)cc1
Show InChI InChI=1S/C19H17BrN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a 8.20n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50149123
PNG
(5-Butyl-9-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]qu...)
Show SMILES CCCCc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-9-17-21-16-11-10-14(20)12-15(16)19-22-18(23-24(17)19)13-7-5-4-6-8-13/h4-8,10-12H,2-3,9H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-DPCPX binding at human adenosine A2B receptor expressed in HEK-293 cells.


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149122
PNG
(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(Br)cc1
Show InChI InChI=1S/C19H17BrN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50149111
PNG
(5-Butyl-2-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-c]...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-DPCPX binding at human adenosine A1 receptor expressed in CHO cells.


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149125
PNG
(5-Butyl-8-chloro-2-(4-chloro-phenyl)-[1,2,4]triazo...)
Show SMILES CCCCc1nc2cc(Cl)ccc2c2nc(nn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H16Cl2N4/c1-2-3-4-17-22-16-11-14(21)9-10-15(16)19-23-18(24-25(17)19)12-5-7-13(20)8-6-12/h5-11H,2-4H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50145226
PNG
(5-Butyl-2-phenyl-[1,2,4]triazolo[1,5-c]quinazoline...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H18N4/c1-2-3-13-17-20-16-12-8-7-11-15(16)19-21-18(22-23(17)19)14-9-5-4-6-10-14/h4-12H,2-3,13H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-DPCPX binding at human adenosine A2B receptor expressed in HEK-293 cells.


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149104
PNG
(5-Butyl-9-chloro-2-(4-chloro-phenyl)-[1,2,4]triazo...)
Show SMILES CCCCc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H16Cl2N4/c1-2-3-4-17-22-16-10-9-14(21)11-15(16)19-23-18(24-25(17)19)12-5-7-13(20)8-6-12/h5-11H,2-4H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50149123
PNG
(5-Butyl-9-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]qu...)
Show SMILES CCCCc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-9-17-21-16-11-10-14(20)12-15(16)19-22-18(23-24(17)19)13-7-5-4-6-8-13/h4-8,10-12H,2-3,9H2,1H3
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n/an/a>6.20E+3n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-DPCPX binding at human adenosine A1 receptor expressed in CHO cells.


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149125
PNG
(5-Butyl-8-chloro-2-(4-chloro-phenyl)-[1,2,4]triazo...)
Show SMILES CCCCc1nc2cc(Cl)ccc2c2nc(nn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H16Cl2N4/c1-2-3-4-17-22-16-11-14(21)9-10-15(16)19-23-18(24-25(17)19)12-5-7-13(20)8-6-12/h5-11H,2-4H2,1H3
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n/an/a 320n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149108
PNG
(5-Butyl-2-(4-fluoro-phenyl)-[1,2,4]triazolo[1,5-c]...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(F)cc1
Show InChI InChI=1S/C19H17FN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50145226
PNG
(5-Butyl-2-phenyl-[1,2,4]triazolo[1,5-c]quinazoline...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H18N4/c1-2-3-13-17-20-16-12-8-7-11-15(16)19-21-18(22-23(17)19)14-9-5-4-6-10-14/h4-12H,2-3,13H2,1H3
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n/an/a 260n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149123
PNG
(5-Butyl-9-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]qu...)
Show SMILES CCCCc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-9-17-21-16-11-10-14(20)12-15(16)19-22-18(23-24(17)19)13-7-5-4-6-8-13/h4-8,10-12H,2-3,9H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50145231
PNG
(5-Butyl-2-(4-methoxy-phenyl)-[1,2,4]triazolo[1,5-c...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(OC)cc1
Show InChI InChI=1S/C20H20N4O/c1-3-4-9-18-21-17-8-6-5-7-16(17)20-22-19(23-24(18)20)14-10-12-15(25-2)13-11-14/h5-8,10-13H,3-4,9H2,1-2H3
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n/an/a 160n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149119
PNG
(5-Butyl-8-methyl-2-phenyl-[1,2,4]triazolo[1,5-c]qu...)
Show SMILES CCCCc1nc2cc(C)ccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C20H20N4/c1-3-4-10-18-21-17-13-14(2)11-12-16(17)20-22-19(23-24(18)20)15-8-6-5-7-9-15/h5-9,11-13H,3-4,10H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50149122
PNG
(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(Br)cc1
Show InChI InChI=1S/C19H17BrN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-DPCPX binding at human adenosine A1 receptor expressed in CHO cells.


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149104
PNG
(5-Butyl-9-chloro-2-(4-chloro-phenyl)-[1,2,4]triazo...)
Show SMILES CCCCc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H16Cl2N4/c1-2-3-4-17-22-16-10-9-14(21)11-15(16)19-23-18(24-25(17)19)12-5-7-13(20)8-6-12/h5-11H,2-4H2,1H3
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n/an/a 28n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149116
PNG
(4-(5-Butyl-[1,2,4]triazolo[1,5-c]quinazolin-2-yl)-...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(O)cc1
Show InChI InChI=1S/C19H18N4O/c1-2-3-8-17-20-16-7-5-4-6-15(16)19-21-18(22-23(17)19)13-9-11-14(24)12-10-13/h4-7,9-12,24H,2-3,8H2,1H3
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n/an/a 5.30E+3n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50145231
PNG
(5-Butyl-2-(4-methoxy-phenyl)-[1,2,4]triazolo[1,5-c...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(OC)cc1
Show InChI InChI=1S/C20H20N4O/c1-3-4-9-18-21-17-8-6-5-7-16(17)20-22-19(23-24(18)20)14-10-12-15(25-2)13-11-14/h5-8,10-13H,3-4,9H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50145226
PNG
(5-Butyl-2-phenyl-[1,2,4]triazolo[1,5-c]quinazoline...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H18N4/c1-2-3-13-17-20-16-12-8-7-11-15(16)19-21-18(22-23(17)19)14-9-5-4-6-10-14/h4-12H,2-3,13H2,1H3
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n/an/a 2.60E+3n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-DPCPX binding at human adenosine A1 receptor expressed in CHO cells.


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50145226
PNG
(5-Butyl-2-phenyl-[1,2,4]triazolo[1,5-c]quinazoline...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H18N4/c1-2-3-13-17-20-16-12-8-7-11-15(16)19-21-18(22-23(17)19)14-9-5-4-6-10-14/h4-12H,2-3,13H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149123
PNG
(5-Butyl-9-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]qu...)
Show SMILES CCCCc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-9-17-21-16-11-10-14(20)12-15(16)19-22-18(23-24(17)19)13-7-5-4-6-8-13/h4-8,10-12H,2-3,9H2,1H3
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n/an/a 45n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149103
PNG
(5-Butyl-9-chloro-2-(4-methoxy-phenyl)-[1,2,4]triaz...)
Show SMILES CCCCc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccc(OC)cc1
Show InChI InChI=1S/C20H19ClN4O/c1-3-4-5-18-22-17-11-8-14(21)12-16(17)20-23-19(24-25(18)20)13-6-9-15(26-2)10-7-13/h6-12H,3-5H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50149115
PNG
(5-Butyl-8-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]qu...)
Show SMILES CCCCc1nc2cc(Cl)ccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-9-17-21-16-12-14(20)10-11-15(16)19-22-18(23-24(17)19)13-7-5-4-6-8-13/h4-8,10-12H,2-3,9H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-DPCPX binding at human adenosine A1 receptor expressed in CHO cells.


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149113
PNG
(5-Butyl-2-(4-ethoxy-phenyl)-[1,2,4]triazolo[1,5-c]...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(OCC)cc1
Show InChI InChI=1S/C21H22N4O/c1-3-5-10-19-22-18-9-7-6-8-17(18)21-23-20(24-25(19)21)15-11-13-16(14-12-15)26-4-2/h6-9,11-14H,3-5,10H2,1-2H3
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n/an/a 35n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149115
PNG
(5-Butyl-8-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]qu...)
Show SMILES CCCCc1nc2cc(Cl)ccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-9-17-21-16-12-14(20)10-11-15(16)19-22-18(23-24(17)19)13-7-5-4-6-8-13/h4-8,10-12H,2-3,9H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50149111
PNG
(5-Butyl-2-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-c]...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-DPCPX binding at human adenosine A2B receptor expressed in HEK-293 cells.


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50149122
PNG
(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(Br)cc1
Show InChI InChI=1S/C19H17BrN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-DPCPX binding at human adenosine A2B receptor expressed in HEK-293 cells.


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50145229
PNG
(5-Butyl-2-(4-trifluoromethyl-phenyl)-[1,2,4]triazo...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H17F3N4/c1-2-3-8-17-24-16-7-5-4-6-15(16)19-25-18(26-27(17)19)13-9-11-14(12-10-13)20(21,22)23/h4-7,9-12H,2-3,8H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149114
PNG
(5-Butyl-10-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]q...)
Show SMILES CCCCc1nc2cccc(Cl)c2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H17ClN4/c1-2-3-12-16-21-15-11-7-10-14(20)17(15)19-22-18(23-24(16)19)13-8-5-4-6-9-13/h4-11H,2-3,12H2,1H3
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n/an/a 1.00E+3n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 3775-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.099
BindingDB Entry DOI: 10.7270/Q21R6PZM
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50145226
PNG
(5-Butyl-2-phenyl-[1,2,4]triazolo[1,5-c]quinazoline...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H18N4/c1-2-3-13-17-20-16-12-8-7-11-15(16)19-21-18(22-23(17)19)14-9-5-4-6-10-14/h4-12H,2-3,13H2,1H3
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n/an/a 260n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Binding affinity for human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 2443-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.010
BindingDB Entry DOI: 10.7270/Q21C1W9W
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50145229
PNG
(5-Butyl-2-(4-trifluoromethyl-phenyl)-[1,2,4]triazo...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H17F3N4/c1-2-3-8-17-24-16-7-5-4-6-15(16)19-25-18(26-27(17)19)13-9-11-14(12-10-13)20(21,22)23/h4-7,9-12H,2-3,8H2,1H3
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n/an/a 490n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Binding affinity for human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 2443-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.010
BindingDB Entry DOI: 10.7270/Q21C1W9W
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50145229
PNG
(5-Butyl-2-(4-trifluoromethyl-phenyl)-[1,2,4]triazo...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H17F3N4/c1-2-3-8-17-24-16-7-5-4-6-15(16)19-25-18(26-27(17)19)13-9-11-14(12-10-13)20(21,22)23/h4-7,9-12H,2-3,8H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Binding affinity for human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 2443-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.010
BindingDB Entry DOI: 10.7270/Q21C1W9W
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50145226
PNG
(5-Butyl-2-phenyl-[1,2,4]triazolo[1,5-c]quinazoline...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C19H18N4/c1-2-3-13-17-20-16-12-8-7-11-15(16)19-21-18(22-23(17)19)14-9-5-4-6-10-14/h4-12H,2-3,13H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Binding affinity for human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 2443-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.010
BindingDB Entry DOI: 10.7270/Q21C1W9W
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50145231
PNG
(5-Butyl-2-(4-methoxy-phenyl)-[1,2,4]triazolo[1,5-c...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(OC)cc1
Show InChI InChI=1S/C20H20N4O/c1-3-4-9-18-21-17-8-6-5-7-16(17)20-22-19(23-24(18)20)14-10-12-15(25-2)13-11-14/h5-8,10-13H,3-4,9H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Binding affinity for human adenosine A2A receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 2443-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.010
BindingDB Entry DOI: 10.7270/Q21C1W9W
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50145231
PNG
(5-Butyl-2-(4-methoxy-phenyl)-[1,2,4]triazolo[1,5-c...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(OC)cc1
Show InChI InChI=1S/C20H20N4O/c1-3-4-9-18-21-17-8-6-5-7-16(17)20-22-19(23-24(18)20)14-10-12-15(25-2)13-11-14/h5-8,10-13H,3-4,9H2,1-2H3
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n/an/a 160n/an/an/an/an/an/a



Otsuka Pharmaceutical Factory, Inc.

Curated by ChEMBL


Assay Description
Binding affinity for human adenosine A3 receptor expressed in HEK-293 cells


Bioorg Med Chem Lett 14: 2443-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.010
BindingDB Entry DOI: 10.7270/Q21C1W9W
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50149122
PNG
(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(Br)cc1
Show InChI InChI=1S/C19H17BrN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a 8.20n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Displacement of [125I]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counter


J Med Chem 55: 5676-703 (2012)


Article DOI: 10.1021/jm300087j
BindingDB Entry DOI: 10.7270/Q25H7HDK
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50149122
PNG
(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Show SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(Br)cc1
Show InChI InChI=1S/C19H17BrN4/c1-2-3-8-17-21-16-7-5-4-6-15(16)19-22-18(23-24(17)19)13-9-11-14(20)12-10-13/h4-7,9-12H,2-3,8H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in CHO cells after 60 mins by gamma counter


J Med Chem 55: 5676-703 (2012)


Article DOI: 10.1021/jm300087j
BindingDB Entry DOI: 10.7270/Q25H7HDK
More data for this
Ligand-Target Pair
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