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1 similar compounds to monomer 50145587

Compile data set for download or QSAR
Wt: 311.3
BDBM50145585

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50145585   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50145585
PNG
(CHEMBL3765362)
Show SMILES O=C(NCCN1CCN(CC1)c1ccccn1)c1ccncc1
Show InChI InChI=1S/C17H21N5O/c23-17(15-4-7-18-8-5-15)20-9-10-21-11-13-22(14-12-21)16-3-1-2-6-19-16/h1-8H,9-14H2,(H,20,23)
KEGG

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.10n/an/an/an/an/an/an/an/a



Dipartimento di Farmacia Universit£ di Napoli"Federico II"

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex incubated for 30 mins by liquid scintillation counting analysis


Eur J Med Chem 110: 133-50 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.021
BindingDB Entry DOI: 10.7270/Q24X59N9
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50145585
PNG
(CHEMBL3765362)
Show SMILES O=C(NCCN1CCN(CC1)c1ccccn1)c1ccncc1
Show InChI InChI=1S/C17H21N5O/c23-17(15-4-7-18-8-5-15)20-9-10-21-11-13-22(14-12-21)16-3-1-2-6-19-16/h1-8H,9-14H2,(H,20,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Dipartimento di Farmacia Universit£ di Napoli"Federico II"

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat brain cortex incubated for 15 mins by liquid scintillation counting analysis


Eur J Med Chem 110: 133-50 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.021
BindingDB Entry DOI: 10.7270/Q24X59N9
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50145585
PNG
(CHEMBL3765362)
Show SMILES O=C(NCCN1CCN(CC1)c1ccccn1)c1ccncc1
Show InChI InChI=1S/C17H21N5O/c23-17(15-4-7-18-8-5-15)20-9-10-21-11-13-22(14-12-21)16-3-1-2-6-19-16/h1-8H,9-14H2,(H,20,23)
Reactome pathway
KEGG

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Dipartimento di Farmacia Universit£ di Napoli"Federico II"

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum incubated for 15 mins by liquid scintillation counting analysis


Eur J Med Chem 110: 133-50 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.021
BindingDB Entry DOI: 10.7270/Q24X59N9
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (Rat))
BDBM50145585
PNG
(CHEMBL3765362)
Show SMILES O=C(NCCN1CCN(CC1)c1ccccn1)c1ccncc1
Show InChI InChI=1S/C17H21N5O/c23-17(15-4-7-18-8-5-15)20-9-10-21-11-13-22(14-12-21)16-3-1-2-6-19-16/h1-8H,9-14H2,(H,20,23)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Dipartimento di Farmacia Universit£ di Napoli"Federico II"

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from 5HT2C receptor in Sprague-Dawley rat brain cortex incubated for 15 mins by liquid scintillation counting analysi...


Eur J Med Chem 110: 133-50 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.021
BindingDB Entry DOI: 10.7270/Q24X59N9
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM50145585
PNG
(CHEMBL3765362)
Show SMILES O=C(NCCN1CCN(CC1)c1ccccn1)c1ccncc1
Show InChI InChI=1S/C17H21N5O/c23-17(15-4-7-18-8-5-15)20-9-10-21-11-13-22(14-12-21)16-3-1-2-6-19-16/h1-8H,9-14H2,(H,20,23)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Dipartimento di Farmacia Universit£ di Napoli"Federico II"

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-23390 from dopamine D1 receptor in rat striatum incubated for 15 mins by liquid scintillation counting analysis


Eur J Med Chem 110: 133-50 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.021
BindingDB Entry DOI: 10.7270/Q24X59N9
More data for this
Ligand-Target Pair