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1 similar compounds to monomer 50145624

Compile data set for download or QSAR
Wt: 550.9
BDBM50145656

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145656   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tryptophan 5-hydroxylase 1


(Homo sapiens (Human))
BDBM50145656
PNG
(CHEMBL3764128)
Show SMILES Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1cncc(n1)N1CCC2(CNC(C2)C(O)=O)CC1)C(F)(F)F
Show InChI InChI=1S/C25H26ClF3N6O3/c1-15-4-7-35(33-15)19-10-16(26)2-3-17(19)22(25(27,28)29)38-21-13-30-12-20(32-21)34-8-5-24(6-9-34)11-18(23(36)37)31-14-24/h2-4,7,10,12-13,18,22,31H,5-6,8-9,11,14H2,1H3,(H,36,37)/t18?,22-/m1/s1
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Similars

Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Karos Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of TPH1 (unknown origin)


Bioorg Med Chem Lett 26: 1124-9 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.064
BindingDB Entry DOI: 10.7270/Q2WD42DJ
More data for this
Ligand-Target Pair