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2 similar compounds to monomer 50142440

Compile data set for download or QSAR
Wt: 401.4
BDBM50146173
Wt: 292.4
BDBM50214325

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146173,50214325   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ionotropic glutamate receptor NMDA 1/2D


(RAT)
BDBM50214325
PNG
(CHEMBL328571)
Show SMILES Oc1nc2cc(Br)c(Cl)[n+]([O-])c2nc1O
Show InChI InChI=1S/C7H3BrClN3O3/c8-2-1-3-5(12(15)4(2)9)11-7(14)6(13)10-3/h1H,(H,10,13)(H,11,14)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

112n/an/an/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity for glycine site on the NMDA receptor.


Citation and Details
More data for this
Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 3


(Homo sapiens (Human))
BDBM50146173
PNG
(CHEMBL3763725)
Show SMILES O=C(Nc1ccc2CCc3ccccc3N(C(=O)Cn3cccc3)c2c1)OC1CC1
Show InChI InChI=1S/C24H23N3O3/c28-23(16-26-13-3-4-14-26)27-21-6-2-1-5-17(21)7-8-18-9-10-19(15-22(18)27)25-24(29)30-20-11-12-20/h1-6,9-10,13-15,20H,7-8,11-12,16H2,(H,25,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 22n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inverse agonist activity at GST tagged-human CAR-LBD assessed as reduction in fluorescein-PGC1 alpha coactivator recruitment after 1 hr by TR-FRET as...


Eur J Med Chem 108: 505-28 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.018
BindingDB Entry DOI: 10.7270/Q2BG2QV6
More data for this
Ligand-Target Pair