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15 similar compounds to monomer 50440588

Compile data set for download or QSAR
Wt: 384.4
BDBM50152300
Wt: 356.4
BDBM50152305
Wt: 329.4
BDBM50346208
Wt: 466.6
BDBM50440571
Purchase
Wt: 439.5
BDBM50440577
Wt: 412.5
BDBM50440582
Wt: 424.5
BDBM50440583
Wt: 410.5
BDBM50440584
Wt: 495.6
BDBM50440587
Wt: 438.6
BDBM50440589
Wt: 453.6
BDBM50440592
Wt: 412.5
BDBM50440593
Wt: 452.6
BDBM50440597
Wt: 424.6
BDBM50440598
Wt: 438.6
BDBM50440603

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 144 hits for monomerid = 50152300,50152305,50346208,50440571,50440577,50440582,50440583,50440584,50440587,50440589,50440592,50440593,50440597,50440598,50440603   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50346208
PNG
((1-isopropylpiperidin-4-yl)(4-(piperidin-1-ylmethy...)
Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C20H31N3O/c1-17(2)22-12-14-23(15-13-22)20(24)19-8-6-18(7-9-19)16-21-10-4-3-5-11-21/h6-9,17H,3-5,10-16H2,1-2H3
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0.800n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cells


Eur J Med Chem 44: 4413-25 (2009)


Article DOI: 10.1016/j.ejmech.2009.06.007
BindingDB Entry DOI: 10.7270/Q28S4Q7C
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50346208
PNG
((1-isopropylpiperidin-4-yl)(4-(piperidin-1-ylmethy...)
Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C20H31N3O/c1-17(2)22-12-14-23(15-13-22)20(24)19-8-6-18(7-9-19)16-21-10-4-3-5-11-21/h6-9,17H,3-5,10-16H2,1-2H3
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1.30n/an/an/an/an/an/an/an/a



Janssen Pharmaceutical Company

Curated by ChEMBL


Assay Description
Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 mins


ACS Med Chem Lett 6: 450-4 (2015)


Article DOI: 10.1021/ml5005156
BindingDB Entry DOI: 10.7270/Q22F7Q59
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50152305
PNG
(Biphenyl-4-carboxylic acid (1-benzyl-pyrrolidin-3-...)
Show SMILES O=C(NC1CCN(Cc2ccccc2)C1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C24H24N2O/c27-24(22-13-11-21(12-14-22)20-9-5-2-6-10-20)25-23-15-16-26(18-23)17-19-7-3-1-4-8-19/h1-14,23H,15-18H2,(H,25,27)
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3n/an/an/an/an/an/an/an/a



NPS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cells


Bioorg Med Chem Lett 14: 4847-50 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.045
BindingDB Entry DOI: 10.7270/Q20C4V7D
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50346208
PNG
((1-isopropylpiperidin-4-yl)(4-(piperidin-1-ylmethy...)
Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C20H31N3O/c1-17(2)22-12-14-23(15-13-22)20(24)19-8-6-18(7-9-19)16-21-10-4-3-5-11-21/h6-9,17H,3-5,10-16H2,1-2H3
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5n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat cortical hemispheres


Eur J Med Chem 44: 4413-25 (2009)


Article DOI: 10.1016/j.ejmech.2009.06.007
BindingDB Entry DOI: 10.7270/Q28S4Q7C
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50152300
PNG
(4''-Formyl-biphenyl-4-carboxylic acid (1-benzyl-py...)
Show SMILES O=Cc1ccc(cc1)-c1ccc(cc1)C(=O)NC1CCN(Cc2ccccc2)C1
Show InChI InChI=1S/C25H24N2O2/c28-18-20-6-8-21(9-7-20)22-10-12-23(13-11-22)25(29)26-24-14-15-27(17-24)16-19-4-2-1-3-5-19/h1-13,18,24H,14-17H2,(H,26,29)
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70n/an/an/an/an/an/an/an/a



NPS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cells


Bioorg Med Chem Lett 14: 4847-50 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.045
BindingDB Entry DOI: 10.7270/Q20C4V7D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50152305
PNG
(Biphenyl-4-carboxylic acid (1-benzyl-pyrrolidin-3-...)
Show SMILES O=C(NC1CCN(Cc2ccccc2)C1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C24H24N2O/c27-24(22-13-11-21(12-14-22)20-9-5-2-6-10-20)25-23-15-16-26(18-23)17-19-7-3-1-4-8-19/h1-14,23H,15-18H2,(H,25,27)
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600n/an/an/an/an/an/an/an/a



NPS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cells


Bioorg Med Chem Lett 14: 4847-50 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.045
BindingDB Entry DOI: 10.7270/Q20C4V7D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50152300
PNG
(4''-Formyl-biphenyl-4-carboxylic acid (1-benzyl-py...)
Show SMILES O=Cc1ccc(cc1)-c1ccc(cc1)C(=O)NC1CCN(Cc2ccccc2)C1
Show InChI InChI=1S/C25H24N2O2/c28-18-20-6-8-21(9-7-20)22-10-12-23(13-11-22)25(29)26-24-14-15-27(17-24)16-19-4-2-1-3-5-19/h1-13,18,24H,14-17H2,(H,26,29)
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3.70E+3n/an/an/an/an/an/an/an/a



NPS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cells


Bioorg Med Chem Lett 14: 4847-50 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.045
BindingDB Entry DOI: 10.7270/Q20C4V7D
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50152305
PNG
(Biphenyl-4-carboxylic acid (1-benzyl-pyrrolidin-3-...)
Show SMILES O=C(NC1CCN(Cc2ccccc2)C1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C24H24N2O/c27-24(22-13-11-21(12-14-22)20-9-5-2-6-10-20)25-23-15-16-26(18-23)17-19-7-3-1-4-8-19/h1-14,23H,15-18H2,(H,25,27)
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n/an/a 1.50E+3n/an/an/an/an/an/a



NPS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration required to reverse the dopamine inhibition of forskolin-stimulated adenyl cyclase activity in CHO cells stably expressing h...


Bioorg Med Chem Lett 14: 4847-50 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.045
BindingDB Entry DOI: 10.7270/Q20C4V7D
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50346208
PNG
((1-isopropylpiperidin-4-yl)(4-(piperidin-1-ylmethy...)
Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C20H31N3O/c1-17(2)22-12-14-23(15-13-22)20(24)19-8-6-18(7-9-19)16-21-10-4-3-5-11-21/h6-9,17H,3-5,10-16H2,1-2H3
PDB
MMDB

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n/an/a>3.00E+4n/an/an/an/an/an/a



Janssen Pharmaceutical Company

Curated by ChEMBL


Assay Description
Displacement of [3H]-astemizole from human ERG expressed in HEK293 cells after 60 mins by scintillation counting analysis


ACS Med Chem Lett 6: 450-4 (2015)


Article DOI: 10.1021/ml5005156
BindingDB Entry DOI: 10.7270/Q22F7Q59
More data for this
Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1)


(Homo sapiens (Human))
BDBM50440571
PNG
(CHEMBL2426474)
Show SMILES O=C(N1CCC(CC1)N1CCCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C28H42N4O2/c33-27(31-19-11-25(12-20-31)29-15-3-1-4-16-29)23-7-9-24(10-8-23)28(34)32-21-13-26(14-22-32)30-17-5-2-6-18-30/h7-10,25-26H,1-6,11-22H2
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n/an/a 4.90E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1)


(Homo sapiens (Human))
BDBM50440577
PNG
(CHEMBL2426468)
Show SMILES CN1CCN2CC(CC2C1)NC(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C25H37N5O2/c1-27-14-15-30-17-21(16-23(30)18-27)26-24(31)19-4-6-20(7-5-19)25(32)29-12-8-22(9-13-29)28-10-2-3-11-28/h4-7,21-23H,2-3,8-18H2,1H3,(H,26,31)
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1)


(Homo sapiens (Human))
BDBM50440582
PNG
(CHEMBL2426463)
Show SMILES O=C(NCCCN1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H36N4O2/c29-23(25-12-5-15-26-13-1-2-14-26)20-6-8-21(9-7-20)24(30)28-18-10-22(11-19-28)27-16-3-4-17-27/h6-9,22H,1-5,10-19H2,(H,25,29)
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1)


(Homo sapiens (Human))
BDBM50440583
PNG
(CHEMBL2426462)
Show SMILES O=C(N1CCC(C1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C25H36N4O2/c30-24(28-16-9-22(10-17-28)26-12-1-2-13-26)20-5-7-21(8-6-20)25(31)29-18-11-23(19-29)27-14-3-4-15-27/h5-8,22-23H,1-4,9-19H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1)


(Homo sapiens (Human))
BDBM50440584
PNG
(CHEMBL2426461)
Show SMILES O=C(N1CC(C1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H34N4O2/c29-23(27-15-9-21(10-16-27)25-11-1-2-12-25)19-5-7-20(8-6-19)24(30)28-17-22(18-28)26-13-3-4-14-26/h5-8,21-22H,1-4,9-18H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1)


(Homo sapiens (Human))
BDBM50440587
PNG
(CHEMBL2426494)
Show SMILES CC(C1CCN(CC1)C(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1)N1CCN(C)CC1
Show InChI InChI=1S/C29H45N5O2/c1-23(31-21-19-30(2)20-22-31)24-9-15-33(16-10-24)28(35)25-5-7-26(8-6-25)29(36)34-17-11-27(12-18-34)32-13-3-4-14-32/h5-8,23-24,27H,3-4,9-22H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1)


(Homo sapiens (Human))
BDBM50440589
PNG
(CHEMBL2426492)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCN(CC1)C1CCCC1
Show InChI InChI=1S/C26H38N4O2/c31-25(29-15-11-24(12-16-29)27-13-3-4-14-27)21-7-9-22(10-8-21)26(32)30-19-17-28(18-20-30)23-5-1-2-6-23/h7-10,23-24H,1-6,11-20H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1)


(Homo sapiens (Human))
BDBM50440592
PNG
(CHEMBL2426489)
Show SMILES C[N+]1(CCCC1)C1CCN(CC1)C(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C27H41N4O2/c1-31(20-4-5-21-31)25-12-18-30(19-13-25)27(33)23-8-6-22(7-9-23)26(32)29-16-10-24(11-17-29)28-14-2-3-15-28/h6-9,24-25H,2-5,10-21H2,1H3/q+1
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1)


(Homo sapiens (Human))
BDBM50440593
PNG
(CHEMBL2426488)
Show SMILES CN(C)C1CCN(CC1)C(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H36N4O2/c1-25(2)21-9-15-27(16-10-21)23(29)19-5-7-20(8-6-19)24(30)28-17-11-22(12-18-28)26-13-3-4-14-26/h5-8,21-22H,3-4,9-18H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1)


(Homo sapiens (Human))
BDBM50440597
PNG
(CHEMBL2426484)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C27H40N4O2/c32-26(30-18-10-24(11-19-30)28-14-2-1-3-15-28)22-6-8-23(9-7-22)27(33)31-20-12-25(13-21-31)29-16-4-5-17-29/h6-9,24-25H,1-5,10-21H2
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n/an/a 1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1)


(Homo sapiens (Human))
BDBM50440598
PNG
(CHEMBL2426483)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(CN2CCC(CC2)N2CCCC2)cc1
Show InChI InChI=1S/C26H40N4O/c31-26(30-19-11-25(12-20-30)29-15-3-4-16-29)23-7-5-22(6-8-23)21-27-17-9-24(10-18-27)28-13-1-2-14-28/h5-8,24-25H,1-4,9-21H2
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n/an/a 8.10E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1)


(Homo sapiens (Human))
BDBM50440603
PNG
(CHEMBL2426498)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C26H38N4O2/c31-25(29-17-9-23(10-18-29)27-13-1-2-14-27)21-5-7-22(8-6-21)26(32)30-19-11-24(12-20-30)28-15-3-4-16-28/h5-8,23-24H,1-4,9-20H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Scm-like with four MBT domains protein 1


(Homo sapiens (Human))
BDBM50440571
PNG
(CHEMBL2426474)
Show SMILES O=C(N1CCC(CC1)N1CCCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C28H42N4O2/c33-27(31-19-11-25(12-20-31)29-15-3-1-4-16-29)23-7-9-24(10-8-23)28(34)32-21-13-26(14-22-32)30-17-5-2-6-18-30/h7-10,25-26H,1-6,11-22H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of SFMBT1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Scm-like with four MBT domains protein 1


(Homo sapiens (Human))
BDBM50440577
PNG
(CHEMBL2426468)
Show SMILES CN1CCN2CC(CC2C1)NC(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C25H37N5O2/c1-27-14-15-30-17-21(16-23(30)18-27)26-24(31)19-4-6-20(7-5-19)25(32)29-12-8-22(9-13-29)28-10-2-3-11-28/h4-7,21-23H,2-3,8-18H2,1H3,(H,26,31)
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of SFMBT1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Scm-like with four MBT domains protein 1


(Homo sapiens (Human))
BDBM50440582
PNG
(CHEMBL2426463)
Show SMILES O=C(NCCCN1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H36N4O2/c29-23(25-12-5-15-26-13-1-2-14-26)20-6-8-21(9-7-20)24(30)28-18-10-22(11-19-28)27-16-3-4-17-27/h6-9,22H,1-5,10-19H2,(H,25,29)
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of SFMBT1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Scm-like with four MBT domains protein 1


(Homo sapiens (Human))
BDBM50440583
PNG
(CHEMBL2426462)
Show SMILES O=C(N1CCC(C1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C25H36N4O2/c30-24(28-16-9-22(10-17-28)26-12-1-2-13-26)20-5-7-21(8-6-20)25(31)29-18-11-23(19-29)27-14-3-4-15-27/h5-8,22-23H,1-4,9-19H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of SFMBT1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Scm-like with four MBT domains protein 1


(Homo sapiens (Human))
BDBM50440584
PNG
(CHEMBL2426461)
Show SMILES O=C(N1CC(C1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H34N4O2/c29-23(27-15-9-21(10-16-27)25-11-1-2-12-25)19-5-7-20(8-6-19)24(30)28-17-22(18-28)26-13-3-4-14-26/h5-8,21-22H,1-4,9-18H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of SFMBT1 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440577
PNG
(CHEMBL2426468)
Show SMILES CN1CCN2CC(CC2C1)NC(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C25H37N5O2/c1-27-14-15-30-17-21(16-23(30)18-27)26-24(31)19-4-6-20(7-5-19)25(32)29-12-8-22(9-13-29)28-10-2-3-11-28/h4-7,21-23H,2-3,8-18H2,1H3,(H,26,31)
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n/an/a 4.60E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440582
PNG
(CHEMBL2426463)
Show SMILES O=C(NCCCN1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H36N4O2/c29-23(25-12-5-15-26-13-1-2-14-26)20-6-8-21(9-7-20)24(30)28-18-10-22(11-19-28)27-16-3-4-17-27/h6-9,22H,1-5,10-19H2,(H,25,29)
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n/an/a 680n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440583
PNG
(CHEMBL2426462)
Show SMILES O=C(N1CCC(C1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C25H36N4O2/c30-24(28-16-9-22(10-17-28)26-12-1-2-13-26)20-5-7-21(8-6-20)25(31)29-18-11-23(19-29)27-14-3-4-15-27/h5-8,22-23H,1-4,9-19H2
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n/an/a 250n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440584
PNG
(CHEMBL2426461)
Show SMILES O=C(N1CC(C1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H34N4O2/c29-23(27-15-9-21(10-16-27)25-11-1-2-12-25)19-5-7-20(8-6-19)24(30)28-17-22(18-28)26-13-3-4-14-26/h5-8,21-22H,1-4,9-18H2
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n/an/a 330n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440587
PNG
(CHEMBL2426494)
Show SMILES CC(C1CCN(CC1)C(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1)N1CCN(C)CC1
Show InChI InChI=1S/C29H45N5O2/c1-23(31-21-19-30(2)20-22-31)24-9-15-33(16-10-24)28(35)25-5-7-26(8-6-25)29(36)34-17-11-27(12-18-34)32-13-3-4-14-32/h5-8,23-24,27H,3-4,9-22H2,1-2H3
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n/an/a 300n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440589
PNG
(CHEMBL2426492)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCN(CC1)C1CCCC1
Show InChI InChI=1S/C26H38N4O2/c31-25(29-15-11-24(12-16-29)27-13-3-4-14-27)21-7-9-22(10-8-21)26(32)30-19-17-28(18-20-30)23-5-1-2-6-23/h7-10,23-24H,1-6,11-20H2
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n/an/a 3.80E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440592
PNG
(CHEMBL2426489)
Show SMILES C[N+]1(CCCC1)C1CCN(CC1)C(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C27H41N4O2/c1-31(20-4-5-21-31)25-12-18-30(19-13-25)27(33)23-8-6-22(7-9-23)26(32)29-16-10-24(11-17-29)28-14-2-3-15-28/h6-9,24-25H,2-5,10-21H2,1H3/q+1
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n/an/a 140n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440593
PNG
(CHEMBL2426488)
Show SMILES CN(C)C1CCN(CC1)C(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H36N4O2/c1-25(2)21-9-15-27(16-10-21)23(29)19-5-7-20(8-6-19)24(30)28-17-11-22(12-18-28)26-13-3-4-14-26/h5-8,21-22H,3-4,9-18H2,1-2H3
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n/an/a 310n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440597
PNG
(CHEMBL2426484)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C27H40N4O2/c32-26(30-18-10-24(11-19-30)28-14-2-1-3-15-28)22-6-8-23(9-7-22)27(33)31-20-12-25(13-21-31)29-16-4-5-17-29/h6-9,24-25H,1-5,10-21H2
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n/an/a 230n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440598
PNG
(CHEMBL2426483)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(CN2CCC(CC2)N2CCCC2)cc1
Show InChI InChI=1S/C26H40N4O/c31-26(30-19-11-25(12-20-30)29-15-3-4-16-29)23-7-5-22(6-8-23)21-27-17-9-24(10-18-27)28-13-1-2-14-28/h5-8,24-25H,1-4,9-21H2
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n/an/a 140n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440603
PNG
(CHEMBL2426498)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C26H38N4O2/c31-25(29-17-9-23(10-18-29)27-13-1-2-14-27)21-5-7-22(8-6-21)26(32)30-19-11-24(12-20-30)28-15-3-4-16-28/h5-8,23-24H,1-4,9-20H2
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n/an/a 71n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440571
PNG
(CHEMBL2426474)
Show SMILES O=C(N1CCC(CC1)N1CCCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C28H42N4O2/c33-27(31-19-11-25(12-20-31)29-15-3-1-4-16-29)23-7-9-24(10-8-23)28(34)32-21-13-26(14-22-32)30-17-5-2-6-18-30/h7-10,25-26H,1-6,11-22H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440577
PNG
(CHEMBL2426468)
Show SMILES CN1CCN2CC(CC2C1)NC(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C25H37N5O2/c1-27-14-15-30-17-21(16-23(30)18-27)26-24(31)19-4-6-20(7-5-19)25(32)29-12-8-22(9-13-29)28-10-2-3-11-28/h4-7,21-23H,2-3,8-18H2,1H3,(H,26,31)
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n/an/a 4.50E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440582
PNG
(CHEMBL2426463)
Show SMILES O=C(NCCCN1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H36N4O2/c29-23(25-12-5-15-26-13-1-2-14-26)20-6-8-21(9-7-20)24(30)28-18-10-22(11-19-28)27-16-3-4-17-27/h6-9,22H,1-5,10-19H2,(H,25,29)
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n/an/a 340n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440583
PNG
(CHEMBL2426462)
Show SMILES O=C(N1CCC(C1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C25H36N4O2/c30-24(28-16-9-22(10-17-28)26-12-1-2-13-26)20-5-7-21(8-6-20)25(31)29-18-11-23(19-29)27-14-3-4-15-27/h5-8,22-23H,1-4,9-19H2
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n/an/a 220n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440584
PNG
(CHEMBL2426461)
Show SMILES O=C(N1CC(C1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H34N4O2/c29-23(27-15-9-21(10-16-27)25-11-1-2-12-25)19-5-7-20(8-6-19)24(30)28-17-22(18-28)26-13-3-4-14-26/h5-8,21-22H,1-4,9-18H2
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n/an/a 300n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440587
PNG
(CHEMBL2426494)
Show SMILES CC(C1CCN(CC1)C(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1)N1CCN(C)CC1
Show InChI InChI=1S/C29H45N5O2/c1-23(31-21-19-30(2)20-22-31)24-9-15-33(16-10-24)28(35)25-5-7-26(8-6-25)29(36)34-17-11-27(12-18-34)32-13-3-4-14-32/h5-8,23-24,27H,3-4,9-22H2,1-2H3
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n/an/a 250n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440589
PNG
(CHEMBL2426492)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCN(CC1)C1CCCC1
Show InChI InChI=1S/C26H38N4O2/c31-25(29-15-11-24(12-16-29)27-13-3-4-14-27)21-7-9-22(10-8-21)26(32)30-19-17-28(18-20-30)23-5-1-2-6-23/h7-10,23-24H,1-6,11-20H2
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n/an/a 3.20E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440592
PNG
(CHEMBL2426489)
Show SMILES C[N+]1(CCCC1)C1CCN(CC1)C(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C27H41N4O2/c1-31(20-4-5-21-31)25-12-18-30(19-13-25)27(33)23-8-6-22(7-9-23)26(32)29-16-10-24(11-17-29)28-14-2-3-15-28/h6-9,24-25H,2-5,10-21H2,1H3/q+1
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n/an/a 81n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440593
PNG
(CHEMBL2426488)
Show SMILES CN(C)C1CCN(CC1)C(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H36N4O2/c1-25(2)21-9-15-27(16-10-21)23(29)19-5-7-20(8-6-19)24(30)28-17-11-22(12-18-28)26-13-3-4-14-26/h5-8,21-22H,3-4,9-18H2,1-2H3
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n/an/a 180n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440597
PNG
(CHEMBL2426484)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C27H40N4O2/c32-26(30-18-10-24(11-19-30)28-14-2-1-3-15-28)22-6-8-23(9-7-22)27(33)31-20-12-25(13-21-31)29-16-4-5-17-29/h6-9,24-25H,1-5,10-21H2
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n/an/a 160n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440598
PNG
(CHEMBL2426483)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(CN2CCC(CC2)N2CCCC2)cc1
Show InChI InChI=1S/C26H40N4O/c31-26(30-19-11-25(12-20-30)29-15-3-4-16-29)23-7-5-22(6-8-23)21-27-17-9-24(10-18-27)28-13-1-2-14-28/h5-8,24-25H,1-4,9-21H2
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n/an/a 130n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440603
PNG
(CHEMBL2426498)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C26H38N4O2/c31-25(29-17-9-23(10-18-29)27-13-1-2-14-27)21-5-7-22(8-6-21)26(32)30-19-11-24(12-20-30)28-15-3-4-16-28/h5-8,23-24H,1-4,9-20H2
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n/an/a 48n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440571
PNG
(CHEMBL2426474)
Show SMILES O=C(N1CCC(CC1)N1CCCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C28H42N4O2/c33-27(31-19-11-25(12-20-31)29-15-3-1-4-16-29)23-7-9-24(10-8-23)28(34)32-21-13-26(14-22-32)30-17-5-2-6-18-30/h7-10,25-26H,1-6,11-22H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
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