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7 similar compounds to monomer 50152891

Compile data set for download or QSAR
Wt: 317.6
BDBM50152886
Wt: 303.6
BDBM50152887
Wt: 283.2
BDBM50152888
Wt: 283.2
BDBM50152878
Wt: 303.6
BDBM50152881
Wt: 345.3
BDBM50152884
Wt: 269.2
BDBM50152885

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50152886,50152887,50152888,50152878,50152881,50152884,50152885   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty acid binding protein muscle


(Homo sapiens (Human))
BDBM50152878
PNG
(2-(Benzyl-methyl-amino)-6-trifluoromethyl-pyrimidi...)
Show SMILES CN(Cc1ccccc1)c1nc(cc(=O)[nH]1)C(F)(F)F
Show InChI InChI=1S/C13H12F3N3O/c1-19(8-9-5-3-2-4-6-9)12-17-10(13(14,15)16)7-11(20)18-12/h2-7H,8H2,1H3,(H,17,18,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Biovitrum AB

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against H-FABP (human-heart and muscle fatty acid binding protein)


Bioorg Med Chem Lett 14: 4449-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.058
BindingDB Entry DOI: 10.7270/Q2SN08FF
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM50152881
PNG
(2-(3-Chloro-benzylamino)-6-trifluoromethyl-pyrimid...)
Show SMILES FC(F)(F)c1cc(=O)[nH]c(NCc2cccc(Cl)c2)n1
Show InChI InChI=1S/C12H9ClF3N3O/c13-8-3-1-2-7(4-8)6-17-11-18-9(12(14,15)16)5-10(20)19-11/h1-5H,6H2,(H2,17,18,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.30E+4n/an/an/an/an/an/a



Biovitrum AB

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against A-FABP (Adipocyte fatty acid binding protein)


Bioorg Med Chem Lett 14: 4449-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.058
BindingDB Entry DOI: 10.7270/Q2SN08FF
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM50152885
PNG
(2-Benzylamino-6-trifluoromethyl-pyrimidin-4-ol | C...)
Show SMILES FC(F)(F)c1cc(=O)[nH]c(NCc2ccccc2)n1
Show InChI InChI=1S/C12H10F3N3O/c13-12(14,15)9-6-10(19)18-11(17-9)16-7-8-4-2-1-3-5-8/h1-6H,7H2,(H2,16,17,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.30E+4n/an/an/an/an/an/a



Biovitrum AB

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against A-FABP (Adipocyte fatty acid binding protein)


Bioorg Med Chem Lett 14: 4449-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.058
BindingDB Entry DOI: 10.7270/Q2SN08FF
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM50152884
PNG
(2-[(Biphenyl-4-ylmethyl)-amino]-6-trifluoromethyl-...)
Show SMILES FC(F)(F)c1cc(=O)[nH]c(NCc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C18H14F3N3O/c19-18(20,21)15-10-16(25)24-17(23-15)22-11-12-6-8-14(9-7-12)13-4-2-1-3-5-13/h1-10H,11H2,(H2,22,23,24,25)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Biovitrum AB

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against A-FABP (Adipocyte fatty acid binding protein)


Bioorg Med Chem Lett 14: 4449-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.058
BindingDB Entry DOI: 10.7270/Q2SN08FF
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM50152878
PNG
(2-(Benzyl-methyl-amino)-6-trifluoromethyl-pyrimidi...)
Show SMILES CN(Cc1ccccc1)c1nc(cc(=O)[nH]1)C(F)(F)F
Show InChI InChI=1S/C13H12F3N3O/c1-19(8-9-5-3-2-4-6-9)12-17-10(13(14,15)16)7-11(20)18-12/h2-7H,8H2,1H3,(H,17,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.40E+4n/an/an/an/an/an/a



Biovitrum AB

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against A-FABP (Adipocyte fatty acid binding protein)


Bioorg Med Chem Lett 14: 4449-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.058
BindingDB Entry DOI: 10.7270/Q2SN08FF
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM50152887
PNG
(2-(2-Chloro-benzylamino)-6-trifluoromethyl-pyrimid...)
Show SMILES FC(F)(F)c1cc(=O)[nH]c(NCc2ccccc2Cl)n1
Show InChI InChI=1S/C12H9ClF3N3O/c13-8-4-2-1-3-7(8)6-17-11-18-9(12(14,15)16)5-10(20)19-11/h1-5H,6H2,(H2,17,18,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



Biovitrum AB

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against A-FABP (Adipocyte fatty acid binding protein)


Bioorg Med Chem Lett 14: 4449-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.058
BindingDB Entry DOI: 10.7270/Q2SN08FF
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM50152888
PNG
(2-(4-Methyl-benzylamino)-6-trifluoromethyl-pyrimid...)
Show SMILES Cc1ccc(CNc2nc(cc(=O)[nH]2)C(F)(F)F)cc1
Show InChI InChI=1S/C13H12F3N3O/c1-8-2-4-9(5-3-8)7-17-12-18-10(13(14,15)16)6-11(20)19-12/h2-6H,7H2,1H3,(H2,17,18,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.30E+4n/an/an/an/an/an/a



Biovitrum AB

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against A-FABP (Adipocyte fatty acid binding protein)


Bioorg Med Chem Lett 14: 4449-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.058
BindingDB Entry DOI: 10.7270/Q2SN08FF
More data for this
Ligand-Target Pair
Fatty acid binding protein muscle


(Homo sapiens (Human))
BDBM50152886
PNG
(2-[(4-Chloro-benzyl)-methyl-amino]-6-trifluorometh...)
Show SMILES CN(Cc1ccc(Cl)cc1)c1nc(cc(=O)[nH]1)C(F)(F)F
Show InChI InChI=1S/C13H11ClF3N3O/c1-20(7-8-2-4-9(14)5-3-8)12-18-10(13(15,16)17)6-11(21)19-12/h2-6H,7H2,1H3,(H,18,19,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Biovitrum AB

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against H-FABP (human-heart and muscle fatty acid binding protein)


Bioorg Med Chem Lett 14: 4449-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.058
BindingDB Entry DOI: 10.7270/Q2SN08FF
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM50152886
PNG
(2-[(4-Chloro-benzyl)-methyl-amino]-6-trifluorometh...)
Show SMILES CN(Cc1ccc(Cl)cc1)c1nc(cc(=O)[nH]1)C(F)(F)F
Show InChI InChI=1S/C13H11ClF3N3O/c1-20(7-8-2-4-9(14)5-3-8)12-18-10(13(15,16)17)6-11(21)19-12/h2-6H,7H2,1H3,(H,18,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Biovitrum AB

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against A-FABP (Adipocyte fatty acid binding protein)


Bioorg Med Chem Lett 14: 4449-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.058
BindingDB Entry DOI: 10.7270/Q2SN08FF
More data for this
Ligand-Target Pair