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2 similar compounds to monomer 50154587

Wt: 230.2
BDBM50154582
Wt: 258.3
BDBM50154586

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50154582,50154586   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase TEC


(Mus musculus)
BDBM50154582
PNG
(6-[1,3]Dioxan-2-yl-quinolin-2-ylamine | CHEMBL4266...)
Show SMILES Nc1ccc2cc(ccc2n1)C1OCCCO1
Show InChI InChI=1S/C13H14N2O2/c14-12-5-3-9-8-10(2-4-11(9)15-12)13-16-6-1-7-17-13/h2-5,8,13H,1,6-7H2,(H2,14,15)
PDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 2.60E+4n/an/an/an/a



The University of Adelaide

Curated by ChEMBL


Assay Description
Displacement of PRP-1 peptide from mouse Tec kinase SH3 domain by fluorescence polarization


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase TEC


(Mus musculus)
BDBM50154582
PNG
(6-[1,3]Dioxan-2-yl-quinolin-2-ylamine | CHEMBL4266...)
Show SMILES Nc1ccc2cc(ccc2n1)C1OCCCO1
Show InChI InChI=1S/C13H14N2O2/c14-12-5-3-9-8-10(2-4-11(9)15-12)13-16-6-1-7-17-13/h2-5,8,13H,1,6-7H2,(H2,14,15)
PDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/a 5.20E+4n/an/an/an/an/a



The University of Adelaide

Curated by ChEMBL


Assay Description
Displacement of PRP-1 peptide from mouse Tec kinase SH3 domain by fluorescence polarization


Citation and Details
More data for this
Ligand-Target Pair
Nck adaptor protein 1


(Homo sapiens)
BDBM50154582
PNG
(6-[1,3]Dioxan-2-yl-quinolin-2-ylamine | CHEMBL4266...)
Show SMILES Nc1ccc2cc(ccc2n1)C1OCCCO1
Show InChI InChI=1S/C13H14N2O2/c14-12-5-3-9-8-10(2-4-11(9)15-12)13-16-6-1-7-17-13/h2-5,8,13H,1,6-7H2,(H2,14,15)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>5.00E+5n/an/an/an/a



The University of Adelaide

Curated by ChEMBL


Assay Description
Displacement of PRP-1 peptide from human Nck kinase SH3 domain by fluorescence polarization


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase TEC


(Mus musculus)
BDBM50154586
PNG
(6-(5,5-Dimethyl-[1,3]dioxan-2-yl)-quinolin-2-ylami...)
Show SMILES CC1(C)COC(OC1)c1ccc2nc(N)ccc2c1
Show InChI InChI=1S/C15H18N2O2/c1-15(2)8-18-14(19-9-15)11-3-5-12-10(7-11)4-6-13(16)17-12/h3-7,14H,8-9H2,1-2H3,(H2,16,17)
PDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/a 2.20E+4n/an/an/an/an/a



The University of Adelaide

Curated by ChEMBL


Assay Description
Displacement of PRP-1 peptide from mouse Tec kinase SH3 domain by fluorescence polarization


Citation and Details
More data for this
Ligand-Target Pair