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1 similar compounds to monomer 50169059

Compile data set for download or QSAR
Wt: 517.9
BDBM50169051

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169051   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM50169051
PNG
(CHEMBL3805576)
Show SMILES CC(C)c1c(NC(=O)Nc2cnc(N3CCCS3(=O)=O)c(c2)C(F)(F)F)cnc2cc(Cl)nn12
Show InChI InChI=1S/C19H19ClF3N7O3S/c1-10(2)16-13(9-24-15-7-14(20)28-30(15)16)27-18(31)26-11-6-12(19(21,22)23)17(25-8-11)29-4-3-5-34(29,32)33/h6-10H,3-5H2,1-2H3,(H2,26,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.00600n/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of MALT1 C domain (329 to 824 residues) (unknown origin) using Ac-Trp-Leu-Arg-Ser-Arg-Cys(PT14)-NH2 as substrate preincubated for 60 mins ...


ACS Med Chem Lett 7: 205-6 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00015
BindingDB Entry DOI: 10.7270/Q2K07658
More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM50169051
PNG
(CHEMBL3805576)
Show SMILES CC(C)c1c(NC(=O)Nc2cnc(N3CCCS3(=O)=O)c(c2)C(F)(F)F)cnc2cc(Cl)nn12
Show InChI InChI=1S/C19H19ClF3N7O3S/c1-10(2)16-13(9-24-15-7-14(20)28-30(15)16)27-18(31)26-11-6-12(19(21,22)23)17(25-8-11)29-4-3-5-34(29,32)33/h6-10H,3-5H2,1-2H3,(H2,26,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.248n/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of MALT1 (unknown origin) expressed in human Jurkat Clone K22 29Q_H23 cells assessed as IL2 production preincubated for 30 mins followed b...


ACS Med Chem Lett 7: 205-6 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00015
BindingDB Entry DOI: 10.7270/Q2K07658
More data for this
Ligand-Target Pair