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1 similar compounds to monomer 50173113

Compile data set for download or QSAR
Wt: 528.6
BDBM50173121

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173121   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ALK tyrosine kinase receptor


(Homo sapiens (Human))
BDBM50173121
PNG
(CHEMBL3808520)
Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2cc(n[nH]2)-c2ccc(NC(=O)Nc3cc(C)on3)c(C)c2)CC1
Show InChI InChI=1S/C28H32N8O3/c1-18-14-22(8-9-23(18)29-28(38)31-26-15-19(2)39-34-26)24-16-25(33-32-24)30-27(37)21-6-4-20(5-7-21)17-36-12-10-35(3)11-13-36/h4-9,14-16H,10-13,17H2,1-3H3,(H2,29,31,34,38)(H2,30,32,33,37)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.64E+3n/an/an/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human ALK (1084 to 1410 residues) expressed in baculovirus infected Sf21 insect cells using polyGlu4:Tyr peptide as substrate after 1 h...


J Med Chem 59: 3906-19 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00106
BindingDB Entry DOI: 10.7270/Q2Z03B2G
More data for this
Ligand-Target Pair