BindingDB logo
myBDB logout

12 similar compounds to monomer 50176718

Compile data set for download or QSAR
Wt: 347.4
BDBM50176721
Wt: 347.4
BDBM50176732
Wt: 341.4
BDBM50176733
Wt: 375.5
BDBM50176709
Wt: 353.4
BDBM50176710
Wt: 339.4
BDBM50176712
Wt: 375.5
BDBM50176713
Wt: 325.4
BDBM50176714
Wt: 327.4
BDBM50176717
Wt: 361.4
BDBM50176719
Wt: 367.5
BDBM50411964
Wt: 381.5
BDBM50411965

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50176721,50176732,50176733,50176709,50176710,50176712,50176713,50176714,50176717,50176719,50411964,50411965   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50176732
PNG
((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-diphenylprop...)
Show SMILES CO[C@@]1(CN2CCC1CC2)C#CC(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H25NO2/c1-26-22(18-24-16-12-19(22)13-17-24)14-15-23(25,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-11,19,25H,12-13,16-18H2,1H3/t22-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.130n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M3 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50176712
PNG
(1-cyclopentyl-3-(3-methoxyquinuclidin-3-yl)-1-phen...)
Show SMILES COC1(CN2CCC1CC2)C#CC(O)(C1CCCC1)c1ccccc1
Show InChI InChI=1/C22H29NO2/c1-25-21(17-23-15-11-18(21)12-16-23)13-14-22(24,20-9-5-6-10-20)19-7-3-2-4-8-19/h2-4,7-8,18,20,24H,5-6,9-12,15-17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.25n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M3 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50176717
PNG
(1-(3-methoxyquinuclidin-3-yl)-3-phenylhept-1-yn-3-...)
Show SMILES CCCCC(O)(C#CC1(CN2CCC1CC2)OC)c1ccccc1
Show InChI InChI=1/C21H29NO2/c1-3-4-12-20(23,18-8-6-5-7-9-18)13-14-21(24-2)17-22-15-10-19(21)11-16-22/h5-9,19,23H,3-4,10-12,15-17H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.630n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M3 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50176732
PNG
((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-diphenylprop...)
Show SMILES CO[C@@]1(CN2CCC1CC2)C#CC(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H25NO2/c1-26-22(18-24-16-12-19(22)13-17-24)14-15-23(25,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-11,19,25H,12-13,16-18H2,1H3/t22-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.790n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M2 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50176714
PNG
(1-cyclobutyl-3-(3-methoxyquinuclidin-3-yl)-1-pheny...)
Show SMILES COC1(CN2CCC1CC2)C#CC(O)(C1CCC1)c1ccccc1
Show InChI InChI=1/C21H27NO2/c1-24-20(16-22-14-10-17(20)11-15-22)12-13-21(23,19-8-5-9-19)18-6-3-2-4-7-18/h2-4,6-7,17,19,23H,5,8-11,14-16H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M3 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50176733
PNG
(1-(3-methoxyquinuclidin-3-yl)-3-phenyloct-1-yn-3-o...)
Show SMILES CCCCCC(O)(C#CC1(CN2CCC1CC2)OC)c1ccccc1
Show InChI InChI=1/C22H31NO2/c1-3-4-8-13-21(24,19-9-6-5-7-10-19)14-15-22(25-2)18-23-16-11-20(22)12-17-23/h5-7,9-10,20,24H,3-4,8,11-13,16-18H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.5n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M3 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50176712
PNG
(1-cyclopentyl-3-(3-methoxyquinuclidin-3-yl)-1-phen...)
Show SMILES COC1(CN2CCC1CC2)C#CC(O)(C1CCCC1)c1ccccc1
Show InChI InChI=1/C22H29NO2/c1-25-21(17-23-15-11-18(21)12-16-23)13-14-22(24,20-9-5-6-10-20)19-7-3-2-4-8-19/h2-4,7-8,18,20,24H,5-6,9-12,15-17H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.20n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M2 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50176710
PNG
((S)-1-cyclohexyl-3-((R)-3-methoxyquinuclidin-3-yl)...)
Show SMILES CO[C@@]1(CN2CCC1CC2)C#C[C@](O)(C1CCCCC1)c1ccccc1
Show InChI InChI=1S/C23H31NO2/c1-26-22(18-24-16-12-19(22)13-17-24)14-15-23(25,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2,4-5,8-9,19,21,25H,3,6-7,10-13,16-18H2,1H3/t22-,23-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.20n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M3 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50176709
PNG
((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-dim-tolylpro...)
Show SMILES CO[C@@]1(CN2CCC1CC2)C#CC(O)(c1cccc(C)c1)c1cccc(C)c1
Show InChI InChI=1S/C25H29NO2/c1-19-6-4-8-22(16-19)25(27,23-9-5-7-20(2)17-23)13-12-24(28-3)18-26-14-10-21(24)11-15-26/h4-9,16-17,21,27H,10-11,14-15,18H2,1-3H3/t24-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
7.90n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M3 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50176714
PNG
(1-cyclobutyl-3-(3-methoxyquinuclidin-3-yl)-1-pheny...)
Show SMILES COC1(CN2CCC1CC2)C#CC(O)(C1CCC1)c1ccccc1
Show InChI InChI=1/C21H27NO2/c1-24-20(16-22-14-10-17(20)11-15-22)12-13-21(23,19-8-5-9-19)18-6-3-2-4-7-18/h2-4,6-7,17,19,23H,5,8-11,14-16H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
13n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M2 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50176710
PNG
((S)-1-cyclohexyl-3-((R)-3-methoxyquinuclidin-3-yl)...)
Show SMILES CO[C@@]1(CN2CCC1CC2)C#C[C@](O)(C1CCCCC1)c1ccccc1
Show InChI InChI=1S/C23H31NO2/c1-26-22(18-24-16-12-19(22)13-17-24)14-15-23(25,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2,4-5,8-9,19,21,25H,3,6-7,10-13,16-18H2,1H3/t22-,23-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
20n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M2 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50176717
PNG
(1-(3-methoxyquinuclidin-3-yl)-3-phenylhept-1-yn-3-...)
Show SMILES CCCCC(O)(C#CC1(CN2CCC1CC2)OC)c1ccccc1
Show InChI InChI=1/C21H29NO2/c1-3-4-12-20(23,18-8-6-5-7-9-18)13-14-21(24-2)17-22-15-10-19(21)11-16-22/h5-9,19,23H,3-4,10-12,15-17H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
25n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M2 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50176719
PNG
(4-(3-methoxyquinuclidin-3-yl)-1,2-diphenylbut-3-yn...)
Show SMILES COC1(CN2CCC1CC2)C#CC(O)(Cc1ccccc1)c1ccccc1
Show InChI InChI=1/C24H27NO2/c1-27-24(19-25-16-12-22(24)13-17-25)15-14-23(26,21-10-6-3-7-11-21)18-20-8-4-2-5-9-20/h2-11,22,26H,12-13,16-19H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
40n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M3 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50176733
PNG
(1-(3-methoxyquinuclidin-3-yl)-3-phenyloct-1-yn-3-o...)
Show SMILES CCCCCC(O)(C#CC1(CN2CCC1CC2)OC)c1ccccc1
Show InChI InChI=1/C22H31NO2/c1-3-4-8-13-21(24,19-9-6-5-7-10-19)14-15-22(25-2)18-23-16-11-20(22)12-17-23/h5-7,9-10,20,24H,3-4,8,11-13,16-18H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
40n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M2 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50176709
PNG
((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-dim-tolylpro...)
Show SMILES CO[C@@]1(CN2CCC1CC2)C#CC(O)(c1cccc(C)c1)c1cccc(C)c1
Show InChI InChI=1S/C25H29NO2/c1-19-6-4-8-22(16-19)25(27,23-9-5-7-20(2)17-23)13-12-24(28-3)18-26-14-10-21(24)11-15-26/h4-9,16-17,21,27H,10-11,14-15,18H2,1-3H3/t24-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
50n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M2 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50176721
PNG
((S)-3-(3-methoxyquinuclidin-3-yl)-1,1-diphenylprop...)
Show SMILES CO[C@]1(CN2CCC1CC2)C#CC(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H25NO2/c1-26-22(18-24-16-12-19(22)13-17-24)14-15-23(25,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-11,19,25H,12-13,16-18H2,1H3/t22-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
63n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M3 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50176713
PNG
((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-dip-tolylpro...)
Show SMILES CO[C@@]1(CN2CCC1CC2)C#CC(O)(c1ccc(C)cc1)c1ccc(C)cc1
Show InChI InChI=1S/C25H29NO2/c1-19-4-8-22(9-5-19)25(27,23-10-6-20(2)7-11-23)15-14-24(28-3)18-26-16-12-21(24)13-17-26/h4-11,21,27H,12-13,16-18H2,1-3H3/t24-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
100n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M3 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50176721
PNG
((S)-3-(3-methoxyquinuclidin-3-yl)-1,1-diphenylprop...)
Show SMILES CO[C@]1(CN2CCC1CC2)C#CC(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H25NO2/c1-26-22(18-24-16-12-19(22)13-17-24)14-15-23(25,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-11,19,25H,12-13,16-18H2,1H3/t22-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
251n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M2 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50176719
PNG
(4-(3-methoxyquinuclidin-3-yl)-1,2-diphenylbut-3-yn...)
Show SMILES COC1(CN2CCC1CC2)C#CC(O)(Cc1ccccc1)c1ccccc1
Show InChI InChI=1/C24H27NO2/c1-27-24(19-25-16-12-22(24)13-17-25)15-14-23(26,21-10-6-3-7-11-21)18-20-8-4-2-5-9-20/h2-11,22,26H,12-13,16-19H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
251n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M2 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50176713
PNG
((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-dip-tolylpro...)
Show SMILES CO[C@@]1(CN2CCC1CC2)C#CC(O)(c1ccc(C)cc1)c1ccc(C)cc1
Show InChI InChI=1S/C25H29NO2/c1-19-4-8-22(9-5-19)25(27,23-10-6-20(2)7-11-23)15-14-24(28-3)18-26-16-12-21(24)13-17-26/h4-11,21,27H,12-13,16-18H2,1-3H3/t24-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
501n/an/an/an/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Binding affinity to human muscarinic M2 receptor


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Cavia porcellus)
BDBM50411964
PNG
(CHEMBL409151)
Show SMILES CO[C@@]1(CN2CCC1CC2)C#C[C@@](O)(C1CCCCCC1)c1ccccc1
Show InChI InChI=1S/C24H33NO2/c1-27-23(19-25-17-13-20(23)14-18-25)15-16-24(26,22-11-7-4-8-12-22)21-9-5-2-3-6-10-21/h4,7-8,11-12,20-21,26H,2-3,5-6,9-10,13-14,17-19H2,1H3/t23-,24-/m1/s1
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 6.31n/an/an/an/an/a



UCB

Curated by ChEMBL


Assay Description
Antagonist activity at muscarinic M3 receptor in carbachol-stimulated guinea pig trachea


Bioorg Med Chem Lett 18: 2675-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.024
BindingDB Entry DOI: 10.7270/Q2KK9D04
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Cavia porcellus)
BDBM50176710
PNG
((S)-1-cyclohexyl-3-((R)-3-methoxyquinuclidin-3-yl)...)
Show SMILES CO[C@@]1(CN2CCC1CC2)C#C[C@](O)(C1CCCCC1)c1ccccc1
Show InChI InChI=1S/C23H31NO2/c1-26-22(18-24-16-12-19(22)13-17-24)14-15-23(25,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2,4-5,8-9,19,21,25H,3,6-7,10-13,16-18H2,1H3/t22-,23-/m1/s1
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.60n/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Antagonism in muscarinic M3 receptor in guinea pig left atria


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Cavia porcellus)
BDBM50176732
PNG
((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-diphenylprop...)
Show SMILES CO[C@@]1(CN2CCC1CC2)C#CC(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H25NO2/c1-26-22(18-24-16-12-19(22)13-17-24)14-15-23(25,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-11,19,25H,12-13,16-18H2,1H3/t22-/m1/s1
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 0.794n/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Antagonism in muscarinic M3 receptor in guinea pig left atria


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Cavia porcellus)
BDBM50176714
PNG
(1-cyclobutyl-3-(3-methoxyquinuclidin-3-yl)-1-pheny...)
Show SMILES COC1(CN2CCC1CC2)C#CC(O)(C1CCC1)c1ccccc1
Show InChI InChI=1/C21H27NO2/c1-24-20(16-22-14-10-17(20)11-15-22)12-13-21(23,19-8-5-9-19)18-6-3-2-4-7-18/h2-4,6-7,17,19,23H,5,8-11,14-16H2,1H3
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 10n/an/an/an/an/a



UCB Pharma

Curated by ChEMBL


Assay Description
Antagonism in muscarinic M3 receptor in guinea pig left atria


Bioorg Med Chem Lett 16: 373-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.079
BindingDB Entry DOI: 10.7270/Q2T72J70
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Cavia porcellus)
BDBM50411965
PNG
(CHEMBL264676)
Show SMILES CO[C@@]1(CN2CCC1CC2)C#C[C@@](O)(C1CCCCCCC1)c1ccccc1
Show InChI InChI=1S/C25H35NO2/c1-28-24(20-26-18-14-21(24)15-19-26)16-17-25(27,23-12-8-5-9-13-23)22-10-6-3-2-4-7-11-22/h5,8-9,12-13,21-22,27H,2-4,6-7,10-11,14-15,18-20H2,1H3/t24-,25-/m1/s1
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 6.31n/an/an/an/an/a



UCB

Curated by ChEMBL


Assay Description
Antagonist activity at muscarinic M3 receptor in carbachol-stimulated guinea pig trachea


Bioorg Med Chem Lett 18: 2675-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.024
BindingDB Entry DOI: 10.7270/Q2KK9D04
More data for this
Ligand-Target Pair