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7 similar compounds to monomer 50267634

Compile data set for download or QSAR
Wt: 337.4
BDBM50176960
Wt: 407.5
BDBM50176971
Wt: 433.6
BDBM50267714
Wt: 451.6
BDBM50267635
Wt: 409.5
BDBM50267636
Wt: 353.4
BDBM50267637
Wt: 419.5
BDBM50267673

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50176960,50176971,50267714,50267635,50267636,50267637,50267673   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50267673
PNG
(CHEMBL521944 | N-cyclopropyl-11-(3-hydroxy-5-(isop...)
Show SMILES CC(C)CCOc1cc(O)cc(OCCCCCCCCCCC(=O)NC2CC2)c1
Show InChI InChI=1S/C25H41NO4/c1-20(2)14-16-30-24-18-22(27)17-23(19-24)29-15-10-8-6-4-3-5-7-9-11-25(28)26-21-12-13-21/h17-21,27H,3-16H2,1-2H3,(H,26,28)
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130n/an/an/an/an/an/an/an/a



Universita degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant CB2 receptor expressed in african green monkey COS cells by radioligand binding assay


J Med Chem 52: 2506-14 (2009)


Article DOI: 10.1021/jm8016255
BindingDB Entry DOI: 10.7270/Q2X34XCN
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50267714
PNG
(CHEMBL491065 | N-(cyclopropylmethyl)-11-(3-hydroxy...)
Show SMILES CC(C)CCOc1cc(O)cc(OCCCCCCCCCCC(=O)NCC2CC2)c1
Show InChI InChI=1S/C26H43NO4/c1-21(2)14-16-31-25-18-23(28)17-24(19-25)30-15-10-8-6-4-3-5-7-9-11-26(29)27-20-22-12-13-22/h17-19,21-22,28H,3-16,20H2,1-2H3,(H,27,29)
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200n/an/an/an/an/an/an/an/a



Universita degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant CB2 receptor expressed in african green monkey COS cells by radioligand binding assay


J Med Chem 52: 2506-14 (2009)


Article DOI: 10.1021/jm8016255
BindingDB Entry DOI: 10.7270/Q2X34XCN
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50267673
PNG
(CHEMBL521944 | N-cyclopropyl-11-(3-hydroxy-5-(isop...)
Show SMILES CC(C)CCOc1cc(O)cc(OCCCCCCCCCCC(=O)NC2CC2)c1
Show InChI InChI=1S/C25H41NO4/c1-20(2)14-16-30-24-18-22(27)17-23(19-24)29-15-10-8-6-4-3-5-7-9-11-25(28)26-21-12-13-21/h17-21,27H,3-16H2,1-2H3,(H,26,28)
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200n/an/an/an/an/an/an/an/a



Universita degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant CB1 receptor expressed in african green monkey COS cells by radioligand binding assay


J Med Chem 52: 2506-14 (2009)


Article DOI: 10.1021/jm8016255
BindingDB Entry DOI: 10.7270/Q2X34XCN
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50267636
PNG
(11-(3-butoxy-5-hydroxyphenoxy)-N-(2-hydroxyethyl)u...)
Show SMILES CCCCOc1cc(O)cc(OCCCCCCCCCCC(=O)NCCO)c1
Show InChI InChI=1S/C23H39NO5/c1-2-3-15-28-21-17-20(26)18-22(19-21)29-16-11-9-7-5-4-6-8-10-12-23(27)24-13-14-25/h17-19,25-26H,2-16H2,1H3,(H,24,27)
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1.62E+3n/an/an/an/an/an/an/an/a



Universita degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant CB2 receptor expressed in african green monkey COS cells by radioligand binding assay


J Med Chem 52: 2506-14 (2009)


Article DOI: 10.1021/jm8016255
BindingDB Entry DOI: 10.7270/Q2X34XCN
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50267714
PNG
(CHEMBL491065 | N-(cyclopropylmethyl)-11-(3-hydroxy...)
Show SMILES CC(C)CCOc1cc(O)cc(OCCCCCCCCCCC(=O)NCC2CC2)c1
Show InChI InChI=1S/C26H43NO4/c1-21(2)14-16-31-25-18-23(28)17-24(19-25)30-15-10-8-6-4-3-5-7-9-11-26(29)27-20-22-12-13-22/h17-19,21-22,28H,3-16,20H2,1-2H3,(H,27,29)
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2.30E+3n/an/an/an/an/an/an/an/a



Universita degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant CB1 receptor expressed in african green monkey COS cells by radioligand binding assay


J Med Chem 52: 2506-14 (2009)


Article DOI: 10.1021/jm8016255
BindingDB Entry DOI: 10.7270/Q2X34XCN
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50267635
PNG
(11-(3-(heptyloxy)-5-hydroxyphenoxy)-N-(2-hydroxyet...)
Show SMILES CCCCCCCOc1cc(O)cc(OCCCCCCCCCCC(=O)NCCO)c1
Show InChI InChI=1S/C26H45NO5/c1-2-3-4-10-13-18-31-24-20-23(29)21-25(22-24)32-19-14-11-8-6-5-7-9-12-15-26(30)27-16-17-28/h20-22,28-29H,2-19H2,1H3,(H,27,30)
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2.42E+3n/an/an/an/an/an/an/an/a



Universita degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant CB2 receptor expressed in african green monkey COS cells by radioligand binding assay


J Med Chem 52: 2506-14 (2009)


Article DOI: 10.1021/jm8016255
BindingDB Entry DOI: 10.7270/Q2X34XCN
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50267636
PNG
(11-(3-butoxy-5-hydroxyphenoxy)-N-(2-hydroxyethyl)u...)
Show SMILES CCCCOc1cc(O)cc(OCCCCCCCCCCC(=O)NCCO)c1
Show InChI InChI=1S/C23H39NO5/c1-2-3-15-28-21-17-20(26)18-22(19-21)29-16-11-9-7-5-4-6-8-10-12-23(27)24-13-14-25/h17-19,25-26H,2-16H2,1H3,(H,24,27)
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2.51E+3n/an/an/an/an/an/an/an/a



Universita degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant CB1 receptor expressed in african green monkey COS cells by radioligand binding assay


J Med Chem 52: 2506-14 (2009)


Article DOI: 10.1021/jm8016255
BindingDB Entry DOI: 10.7270/Q2X34XCN
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50267635
PNG
(11-(3-(heptyloxy)-5-hydroxyphenoxy)-N-(2-hydroxyet...)
Show SMILES CCCCCCCOc1cc(O)cc(OCCCCCCCCCCC(=O)NCCO)c1
Show InChI InChI=1S/C26H45NO5/c1-2-3-4-10-13-18-31-24-20-23(29)21-25(22-24)32-19-14-11-8-6-5-7-9-12-15-26(30)27-16-17-28/h20-22,28-29H,2-19H2,1H3,(H,27,30)
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3.16E+3n/an/an/an/an/an/an/an/a



Universita degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant CB1 receptor expressed in african green monkey COS cells by radioligand binding assay


J Med Chem 52: 2506-14 (2009)


Article DOI: 10.1021/jm8016255
BindingDB Entry DOI: 10.7270/Q2X34XCN
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50176960
PNG
(11-(3-hydroxyphenoxy)undecanoic acid (2-hydroxyeth...)
Show SMILES OCCNC(=O)CCCCCCCCCCOc1cccc(O)c1
Show InChI InChI=1S/C19H31NO4/c21-14-13-20-19(23)12-7-5-3-1-2-4-6-8-15-24-18-11-9-10-17(22)16-18/h9-11,16,21-22H,1-8,12-15H2,(H,20,23)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB1 receptor expressed in COS cells


J Med Chem 48: 7343-50 (2005)


Article DOI: 10.1021/jm0501533
BindingDB Entry DOI: 10.7270/Q2FX7B7W
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50176971
PNG
(16-(3-hydroxyphenoxy)hexadecanoic acid (2-hydroxye...)
Show SMILES OCCNC(=O)CCCCCCCCCCCCCCCOc1cccc(O)c1
Show InChI InChI=1S/C24H41NO4/c26-19-18-25-24(28)17-12-10-8-6-4-2-1-3-5-7-9-11-13-20-29-23-16-14-15-22(27)21-23/h14-16,21,26-27H,1-13,17-20H2,(H,25,28)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB1 receptor expressed in COS cells


J Med Chem 48: 7343-50 (2005)


Article DOI: 10.1021/jm0501533
BindingDB Entry DOI: 10.7270/Q2FX7B7W
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM50267637
PNG
(11-(3,5-Dihydroxyphenoxy)undecanoic Acid (2-Hydrox...)
Show SMILES OCCNC(=O)CCCCCCCCCCOc1cc(O)cc(O)c1
Show InChI InChI=1S/C19H31NO5/c21-11-10-20-19(24)9-7-5-3-1-2-4-6-8-12-25-18-14-16(22)13-17(23)15-18/h13-15,21-23H,1-12H2,(H,20,24)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universita degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to CB2 receptor in rat spleen membrane


J Med Chem 52: 2506-14 (2009)


Article DOI: 10.1021/jm8016255
BindingDB Entry DOI: 10.7270/Q2X34XCN
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM50267637
PNG
(11-(3,5-Dihydroxyphenoxy)undecanoic Acid (2-Hydrox...)
Show SMILES OCCNC(=O)CCCCCCCCCCOc1cc(O)cc(O)c1
Show InChI InChI=1S/C19H31NO5/c21-11-10-20-19(24)9-7-5-3-1-2-4-6-8-12-25-18-14-16(22)13-17(23)15-18/h13-15,21-23H,1-12H2,(H,20,24)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universita degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to CB2 receptor in rat brain membrane


J Med Chem 52: 2506-14 (2009)


Article DOI: 10.1021/jm8016255
BindingDB Entry DOI: 10.7270/Q2X34XCN
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50267637
PNG
(11-(3,5-Dihydroxyphenoxy)undecanoic Acid (2-Hydrox...)
Show SMILES OCCNC(=O)CCCCCCCCCCOc1cc(O)cc(O)c1
Show InChI InChI=1S/C19H31NO5/c21-11-10-20-19(24)9-7-5-3-1-2-4-6-8-12-25-18-14-16(22)13-17(23)15-18/h13-15,21-23H,1-12H2,(H,20,24)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universita degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to CB1 receptor in rat brain membrane


J Med Chem 52: 2506-14 (2009)


Article DOI: 10.1021/jm8016255
BindingDB Entry DOI: 10.7270/Q2X34XCN
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50267637
PNG
(11-(3,5-Dihydroxyphenoxy)undecanoic Acid (2-Hydrox...)
Show SMILES OCCNC(=O)CCCCCCCCCCOc1cc(O)cc(O)c1
Show InChI InChI=1S/C19H31NO5/c21-11-10-20-19(24)9-7-5-3-1-2-4-6-8-12-25-18-14-16(22)13-17(23)15-18/h13-15,21-23H,1-12H2,(H,20,24)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universita degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to CB1 receptor in rat spleen membrane


J Med Chem 52: 2506-14 (2009)


Article DOI: 10.1021/jm8016255
BindingDB Entry DOI: 10.7270/Q2X34XCN
More data for this
Ligand-Target Pair