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6 similar compounds to monomer 50179116

Compile data set for download or QSAR
Wt: 397.5
BDBM50179113
Wt: 395.5
BDBM50179115
Wt: 383.5
BDBM50179121
Wt: 383.5
BDBM50179122
Wt: 409.6
BDBM50179127
Wt: 369.5
BDBM50179131

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 33 hits for monomerid = 50179113,50179115,50179121,50179122,50179127,50179131   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50179121
PNG
((2E,4E)-3-methyl-6-((3,5,5,8,8-pentamethyl-5,6,7,8...)
Show SMILES CCCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C25H37NO2/c1-8-13-26(14-9-10-18(2)15-23(27)28)22-17-21-20(16-19(22)3)24(4,5)11-12-25(21,6)7/h9-10,15-17H,8,11-14H2,1-7H3,(H,27,28)/b10-9+,18-15+
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18n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRalpha


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50179113
PNG
((2E,4E)-6-(butyl(6-tert-butyl-1,1-dimethyl-2,3-dih...)
Show SMILES CCCCN(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C26H39NO2/c1-8-9-14-27(15-10-11-19(2)16-24(28)29)23-18-20(25(3,4)5)17-22-21(23)12-13-26(22,6)7/h10-11,16-18H,8-9,12-15H2,1-7H3,(H,28,29)/b11-10+,19-16+
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21n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRalpha


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50179113
PNG
((2E,4E)-6-(butyl(6-tert-butyl-1,1-dimethyl-2,3-dih...)
Show SMILES CCCCN(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C26H39NO2/c1-8-9-14-27(15-10-11-19(2)16-24(28)29)23-18-20(25(3,4)5)17-22-21(23)12-13-26(22,6)7/h10-11,16-18H,8-9,12-15H2,1-7H3,(H,28,29)/b11-10+,19-16+
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31n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRgamma


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50179131
PNG
((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...)
Show SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H35NO2/c1-8-25(13-9-10-17(2)14-22(26)27)21-16-20-19(15-18(21)3)23(4,5)11-12-24(20,6)7/h9-10,14-16H,8,11-13H2,1-7H3,(H,26,27)/b10-9+,17-14+
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42n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRalpha


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens (Human))
BDBM50179113
PNG
((2E,4E)-6-(butyl(6-tert-butyl-1,1-dimethyl-2,3-dih...)
Show SMILES CCCCN(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C26H39NO2/c1-8-9-14-27(15-10-11-19(2)16-24(28)29)23-18-20(25(3,4)5)17-22-21(23)12-13-26(22,6)7/h10-11,16-18H,8-9,12-15H2,1-7H3,(H,28,29)/b11-10+,19-16+
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60n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRbeta


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50179115
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES C\C(\C=C\CN(CC1CC1)c1cc(cc2c1CCC2(C)C)C(C)(C)C)=C/C(O)=O
Show InChI InChI=1S/C26H37NO2/c1-18(14-24(28)29)8-7-13-27(17-19-9-10-19)23-16-20(25(2,3)4)15-22-21(23)11-12-26(22,5)6/h7-8,14-16,19H,9-13,17H2,1-6H3,(H,28,29)/b8-7+,18-14+
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63n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRalpha


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50179122
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES CC(C)N(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C25H37NO2/c1-17(2)26(13-9-10-18(3)14-23(27)28)22-16-19(24(4,5)6)15-21-20(22)11-12-25(21,7)8/h9-10,14-17H,11-13H2,1-8H3,(H,27,28)/b10-9+,18-14+
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67n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRalpha


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50179131
PNG
((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...)
Show SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H35NO2/c1-8-25(13-9-10-17(2)14-22(26)27)21-16-20-19(15-18(21)3)23(4,5)11-12-24(20,6)7/h9-10,14-16H,8,11-13H2,1-7H3,(H,26,27)/b10-9+,17-14+
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99n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRgamma


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens (Human))
BDBM50179115
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES C\C(\C=C\CN(CC1CC1)c1cc(cc2c1CCC2(C)C)C(C)(C)C)=C/C(O)=O
Show InChI InChI=1S/C26H37NO2/c1-18(14-24(28)29)8-7-13-27(17-19-9-10-19)23-16-20(25(2,3)4)15-22-21(23)11-12-26(22,5)6/h7-8,14-16,19H,9-13,17H2,1-6H3,(H,28,29)/b8-7+,18-14+
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105n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRbeta


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50179122
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES CC(C)N(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C25H37NO2/c1-17(2)26(13-9-10-18(3)14-23(27)28)22-16-19(24(4,5)6)15-21-20(22)11-12-25(21,7)8/h9-10,14-17H,11-13H2,1-8H3,(H,27,28)/b10-9+,18-14+
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121n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRgamma


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50179115
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES C\C(\C=C\CN(CC1CC1)c1cc(cc2c1CCC2(C)C)C(C)(C)C)=C/C(O)=O
Show InChI InChI=1S/C26H37NO2/c1-18(14-24(28)29)8-7-13-27(17-19-9-10-19)23-16-20(25(2,3)4)15-22-21(23)11-12-26(22,5)6/h7-8,14-16,19H,9-13,17H2,1-6H3,(H,28,29)/b8-7+,18-14+
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150n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRgamma


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens (Human))
BDBM50179131
PNG
((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...)
Show SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H35NO2/c1-8-25(13-9-10-17(2)14-22(26)27)21-16-20-19(15-18(21)3)23(4,5)11-12-24(20,6)7/h9-10,14-16H,8,11-13H2,1-7H3,(H,26,27)/b10-9+,17-14+
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152n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRbeta


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens (Human))
BDBM50179121
PNG
((2E,4E)-3-methyl-6-((3,5,5,8,8-pentamethyl-5,6,7,8...)
Show SMILES CCCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C25H37NO2/c1-8-13-26(14-9-10-18(2)15-23(27)28)22-17-21-20(16-19(22)3)24(4,5)11-12-25(21,6)7/h9-10,15-17H,8,11-14H2,1-7H3,(H,27,28)/b10-9+,18-15+
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161n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRbeta


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50179121
PNG
((2E,4E)-3-methyl-6-((3,5,5,8,8-pentamethyl-5,6,7,8...)
Show SMILES CCCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C25H37NO2/c1-8-13-26(14-9-10-18(2)15-23(27)28)22-17-21-20(16-19(22)3)24(4,5)11-12-25(21,6)7/h9-10,15-17H,8,11-14H2,1-7H3,(H,27,28)/b10-9+,18-15+
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211n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRgamma


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50179127
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES CC(C)=CCN(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C27H39NO2/c1-19(2)12-15-28(14-9-10-20(3)16-25(29)30)24-18-21(26(4,5)6)17-23-22(24)11-13-27(23,7)8/h9-10,12,16-18H,11,13-15H2,1-8H3,(H,29,30)/b10-9+,20-16+
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254n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRalpha


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens (Human))
BDBM50179122
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES CC(C)N(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C25H37NO2/c1-17(2)26(13-9-10-18(3)14-23(27)28)22-16-19(24(4,5)6)15-21-20(22)11-12-25(21,7)8/h9-10,14-17H,11-13H2,1-8H3,(H,27,28)/b10-9+,18-14+
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301n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRbeta


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50179127
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES CC(C)=CCN(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C27H39NO2/c1-19(2)12-15-28(14-9-10-20(3)16-25(29)30)24-18-21(26(4,5)6)17-23-22(24)11-13-27(23,7)8/h9-10,12,16-18H,11,13-15H2,1-8H3,(H,29,30)/b10-9+,20-16+
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309n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRgamma


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens (Human))
BDBM50179127
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES CC(C)=CCN(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C27H39NO2/c1-19(2)12-15-28(14-9-10-20(3)16-25(29)30)24-18-21(26(4,5)6)17-23-22(24)11-13-27(23,7)8/h9-10,12,16-18H,11,13-15H2,1-8H3,(H,29,30)/b10-9+,20-16+
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327n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to RXRbeta


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50179131
PNG
((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...)
Show SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H35NO2/c1-8-25(13-9-10-17(2)14-22(26)27)21-16-20-19(15-18(21)3)23(4,5)11-12-24(20,6)7/h9-10,14-16H,8,11-13H2,1-7H3,(H,26,27)/b10-9+,17-14+
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n/an/an/an/a 64n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRalpha in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50179121
PNG
((2E,4E)-3-methyl-6-((3,5,5,8,8-pentamethyl-5,6,7,8...)
Show SMILES CCCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C25H37NO2/c1-8-13-26(14-9-10-18(2)15-23(27)28)22-17-21-20(16-19(22)3)24(4,5)11-12-25(21,6)7/h9-10,15-17H,8,11-14H2,1-7H3,(H,27,28)/b10-9+,18-15+
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n/an/an/an/a 223n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRgamma in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50179115
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES C\C(\C=C\CN(CC1CC1)c1cc(cc2c1CCC2(C)C)C(C)(C)C)=C/C(O)=O
Show InChI InChI=1S/C26H37NO2/c1-18(14-24(28)29)8-7-13-27(17-19-9-10-19)23-16-20(25(2,3)4)15-22-21(23)11-12-26(22,5)6/h7-8,14-16,19H,9-13,17H2,1-6H3,(H,28,29)/b8-7+,18-14+
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n/an/an/an/a 123n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRalpha in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50179113
PNG
((2E,4E)-6-(butyl(6-tert-butyl-1,1-dimethyl-2,3-dih...)
Show SMILES CCCCN(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C26H39NO2/c1-8-9-14-27(15-10-11-19(2)16-24(28)29)23-18-20(25(3,4)5)17-22-21(23)12-13-26(22,6)7/h10-11,16-18H,8-9,12-15H2,1-7H3,(H,28,29)/b11-10+,19-16+
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n/an/an/an/a 53n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRalpha in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens (Human))
BDBM50179131
PNG
((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...)
Show SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H35NO2/c1-8-25(13-9-10-17(2)14-22(26)27)21-16-20-19(15-18(21)3)23(4,5)11-12-24(20,6)7/h9-10,14-16H,8,11-13H2,1-7H3,(H,26,27)/b10-9+,17-14+
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n/an/an/an/a 117n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRbeta in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens (Human))
BDBM50179115
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES C\C(\C=C\CN(CC1CC1)c1cc(cc2c1CCC2(C)C)C(C)(C)C)=C/C(O)=O
Show InChI InChI=1S/C26H37NO2/c1-18(14-24(28)29)8-7-13-27(17-19-9-10-19)23-16-20(25(2,3)4)15-22-21(23)11-12-26(22,5)6/h7-8,14-16,19H,9-13,17H2,1-6H3,(H,28,29)/b8-7+,18-14+
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n/an/an/an/a 98n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRbeta in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50179113
PNG
((2E,4E)-6-(butyl(6-tert-butyl-1,1-dimethyl-2,3-dih...)
Show SMILES CCCCN(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C26H39NO2/c1-8-9-14-27(15-10-11-19(2)16-24(28)29)23-18-20(25(3,4)5)17-22-21(23)12-13-26(22,6)7/h10-11,16-18H,8-9,12-15H2,1-7H3,(H,28,29)/b11-10+,19-16+
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n/an/an/an/a 50n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRgamma in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens (Human))
BDBM50179121
PNG
((2E,4E)-3-methyl-6-((3,5,5,8,8-pentamethyl-5,6,7,8...)
Show SMILES CCCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C25H37NO2/c1-8-13-26(14-9-10-18(2)15-23(27)28)22-17-21-20(16-19(22)3)24(4,5)11-12-25(21,6)7/h9-10,15-17H,8,11-14H2,1-7H3,(H,27,28)/b10-9+,18-15+
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n/an/an/an/a 212n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRbeta in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens (Human))
BDBM50179113
PNG
((2E,4E)-6-(butyl(6-tert-butyl-1,1-dimethyl-2,3-dih...)
Show SMILES CCCCN(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C26H39NO2/c1-8-9-14-27(15-10-11-19(2)16-24(28)29)23-18-20(25(3,4)5)17-22-21(23)12-13-26(22,6)7/h10-11,16-18H,8-9,12-15H2,1-7H3,(H,28,29)/b11-10+,19-16+
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n/an/an/an/a 52n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRbeta in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50179121
PNG
((2E,4E)-3-methyl-6-((3,5,5,8,8-pentamethyl-5,6,7,8...)
Show SMILES CCCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C25H37NO2/c1-8-13-26(14-9-10-18(2)15-23(27)28)22-17-21-20(16-19(22)3)24(4,5)11-12-25(21,6)7/h9-10,15-17H,8,11-14H2,1-7H3,(H,27,28)/b10-9+,18-15+
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n/an/an/an/a 231n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRalpha in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50179122
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES CC(C)N(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C25H37NO2/c1-17(2)26(13-9-10-18(3)14-23(27)28)22-16-19(24(4,5)6)15-21-20(22)11-12-25(21,7)8/h9-10,14-17H,11-13H2,1-8H3,(H,27,28)/b10-9+,18-14+
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n/an/an/an/a 262n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRgamma in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens (Human))
BDBM50179122
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES CC(C)N(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C25H37NO2/c1-17(2)26(13-9-10-18(3)14-23(27)28)22-16-19(24(4,5)6)15-21-20(22)11-12-25(21,7)8/h9-10,14-17H,11-13H2,1-8H3,(H,27,28)/b10-9+,18-14+
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n/an/an/an/a 216n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRbeta in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50179122
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES CC(C)N(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
Show InChI InChI=1S/C25H37NO2/c1-17(2)26(13-9-10-18(3)14-23(27)28)22-16-19(24(4,5)6)15-21-20(22)11-12-25(21,7)8/h9-10,14-17H,11-13H2,1-8H3,(H,27,28)/b10-9+,18-14+
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n/an/an/an/a 252n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRalpha in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50179115
PNG
((2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-...)
Show SMILES C\C(\C=C\CN(CC1CC1)c1cc(cc2c1CCC2(C)C)C(C)(C)C)=C/C(O)=O
Show InChI InChI=1S/C26H37NO2/c1-18(14-24(28)29)8-7-13-27(17-19-9-10-19)23-16-20(25(2,3)4)15-22-21(23)11-12-26(22,5)6/h7-8,14-16,19H,9-13,17H2,1-6H3,(H,28,29)/b8-7+,18-14+
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n/an/an/an/a 100n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRgamma in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50179131
PNG
((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...)
Show SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H35NO2/c1-8-25(13-9-10-17(2)14-22(26)27)21-16-20-19(15-18(21)3)23(4,5)11-12-24(20,6)7/h9-10,14-16H,8,11-13H2,1-7H3,(H,26,27)/b10-9+,17-14+
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n/an/an/an/a 125n/an/an/an/a



Ligand Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Transactivation of RXRgamma in CV1 cells by cotransfection assay


Bioorg Med Chem Lett 16: 2352-6 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.003
BindingDB Entry DOI: 10.7270/Q2S75FW3
More data for this
Ligand-Target Pair