BindingDB logo
myBDB logout

9 similar compounds to monomer 50359505

Compile data set for download or QSAR
Wt: 481.0
BDBM50181796
Wt: 369.1
BDBM50181802
Wt: 732.8
BDBM50181803
Wt: 383.2
BDBM50181806
Wt: 606.9
BDBM50181816
Wt: 606.9
BDBM50181817
Wt: 339.1
BDBM50181823
Wt: 481.0
BDBM50181824
Wt: 356.1
BDBM50212669

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50181796,50181802,50181803,50181806,50181816,50181817,50181823,50181824,50212669   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM50181823
PNG
(CHEMBL425035 | O-phenyl-3-iodotyramine)
Show SMILES NCCc1ccc(Oc2ccccc2)c(I)c1
Show InChI InChI=1S/C14H14INO/c15-13-10-11(8-9-16)6-7-14(13)17-12-4-2-1-3-5-12/h1-7,10H,8-9,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 35n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at mouse TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM50212669
PNG
(2-(4-(4-hydroxyphenoxy)-3-iodophenyl)ethanaminium ...)
Show SMILES [NH3+]CCc1ccc(Oc2ccc(O)cc2)c(I)c1
Show InChI InChI=1S/C14H14INO2/c15-13-9-10(7-8-16)1-6-14(13)18-12-4-2-11(17)3-5-12/h1-6,9,17H,7-8,16H2/p+1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 314n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP production


J Med Chem 50: 2787-98 (2007)


Article DOI: 10.1021/jm0700417
BindingDB Entry DOI: 10.7270/Q2FQ9XF9
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM50181824
PNG
(3,3'-Diiodothyronamine | CHEMBL383495)
Show SMILES NCCc1ccc(Oc2ccc(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C14H13I2NO2/c15-11-8-10(2-3-13(11)18)19-14-4-1-9(5-6-17)7-12(14)16/h1-4,7-8,18H,5-6,17H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 1.00E+3n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at mouse TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Rattus norvegicus (Rat))
BDBM50181817
PNG
(3,3',5'-triiodothyronamine | CHEMBL381531)
Show SMILES NCCc1ccc(Oc2cc(I)c(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C14H12I3NO2/c15-10-5-8(3-4-18)1-2-13(10)20-9-6-11(16)14(19)12(17)7-9/h1-2,5-7,19H,3-4,18H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at rat TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Rattus norvegicus (Rat))
BDBM50181824
PNG
(3,3'-Diiodothyronamine | CHEMBL383495)
Show SMILES NCCc1ccc(Oc2ccc(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C14H13I2NO2/c15-11-8-10(2-3-13(11)18)19-14-4-1-9(5-6-17)7-12(14)16/h1-4,7-8,18H,5-6,17H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 41n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at rat TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Rattus norvegicus (Rat))
BDBM50181823
PNG
(CHEMBL425035 | O-phenyl-3-iodotyramine)
Show SMILES NCCc1ccc(Oc2ccccc2)c(I)c1
Show InChI InChI=1S/C14H14INO/c15-13-10-11(8-9-16)6-7-14(13)17-12-4-2-1-3-5-12/h1-7,10H,8-9,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 2.40n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at rat TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM50181803
PNG
(3,3',5,5'-tetraiodothyronamine | CHEMBL201623)
Show SMILES NCCc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C14H11I4NO2/c15-9-5-8(6-10(16)13(9)20)21-14-11(17)3-7(1-2-19)4-12(14)18/h3-6,20H,1-2,19H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at mouse TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Rattus norvegicus (Rat))
BDBM50181806
PNG
(CHEMBL202395 | N,O-dimethyl-3-iodothyronamine)
Show SMILES CNCCc1ccc(Oc2ccc(OC)cc2)c(I)c1
Show InChI InChI=1S/C16H18INO2/c1-18-10-9-12-3-8-16(15(17)11-12)20-14-6-4-13(19-2)5-7-14/h3-8,11,18H,9-10H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 107n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at rat TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Rattus norvegicus (Rat))
BDBM50181796
PNG
(3,5-Diiodothyronamine | CHEMBL201922)
Show SMILES NCCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Show InChI InChI=1S/C14H13I2NO2/c15-12-7-9(5-6-17)8-13(16)14(12)19-11-3-1-10(18)2-4-11/h1-4,7-8,18H,5-6,17H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 56n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at rat TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM50181796
PNG
(3,5-Diiodothyronamine | CHEMBL201922)
Show SMILES NCCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Show InChI InChI=1S/C14H13I2NO2/c15-12-7-9(5-6-17)8-13(16)14(12)19-11-3-1-10(18)2-4-11/h1-4,7-8,18H,5-6,17H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 371n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at mouse TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Rattus norvegicus (Rat))
BDBM50181803
PNG
(3,3',5,5'-tetraiodothyronamine | CHEMBL201623)
Show SMILES NCCc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C14H11I4NO2/c15-9-5-8(6-10(16)13(9)20)21-14-11(17)3-7(1-2-19)4-12(14)18/h3-6,20H,1-2,19H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at rat TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Rattus norvegicus (Rat))
BDBM50181802
PNG
(CHEMBL202024 | N-methyl-3-iodothyronamine)
Show SMILES CNCCc1ccc(Oc2ccc(O)cc2)c(I)c1
Show InChI InChI=1S/C15H16INO2/c1-17-9-8-11-2-7-15(14(16)10-11)19-13-5-3-12(18)4-6-13/h2-7,10,17-18H,8-9H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 18n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at rat TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM50181806
PNG
(CHEMBL202395 | N,O-dimethyl-3-iodothyronamine)
Show SMILES CNCCc1ccc(Oc2ccc(OC)cc2)c(I)c1
Show InChI InChI=1S/C16H18INO2/c1-18-10-9-12-3-8-16(15(17)11-12)20-14-6-4-13(19-2)5-7-14/h3-8,11,18H,9-10H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at mouse TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Rattus norvegicus (Rat))
BDBM50181816
PNG
(3,3',5-triiodothyronamine | CHEMBL201885)
Show SMILES NCCc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C14H12I3NO2/c15-10-7-9(1-2-13(10)19)20-14-11(16)5-8(3-4-18)6-12(14)17/h1-2,5-7,19H,3-4,18H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 87n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at rat TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM50181817
PNG
(3,3',5'-triiodothyronamine | CHEMBL381531)
Show SMILES NCCc1ccc(Oc2cc(I)c(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C14H12I3NO2/c15-10-5-8(3-4-18)1-2-13(10)20-9-6-11(16)14(19)12(17)7-9/h1-2,5-7,19H,3-4,18H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at mouse TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM50181802
PNG
(CHEMBL202024 | N-methyl-3-iodothyronamine)
Show SMILES CNCCc1ccc(Oc2ccc(O)cc2)c(I)c1
Show InChI InChI=1S/C15H16INO2/c1-17-9-8-11-2-7-15(14(16)10-11)19-13-5-3-12(18)4-6-13/h2-7,10,17-18H,8-9H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 221n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at mouse TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Rattus norvegicus (Rat))
BDBM50212669
PNG
(2-(4-(4-hydroxyphenoxy)-3-iodophenyl)ethanaminium ...)
Show SMILES [NH3+]CCc1ccc(Oc2ccc(O)cc2)c(I)c1
Show InChI InChI=1S/C14H14INO2/c15-13-9-10(7-8-16)1-6-14(13)18-12-4-2-11(17)3-5-12/h1-6,9,17H,7-8,16H2/p+1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 33n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at rat TAAR1 expressed in HEK293 cells assessed as cAMP production


J Med Chem 50: 2787-98 (2007)


Article DOI: 10.1021/jm0700417
BindingDB Entry DOI: 10.7270/Q2FQ9XF9
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM50181816
PNG
(3,3',5-triiodothyronamine | CHEMBL201885)
Show SMILES NCCc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C14H12I3NO2/c15-10-7-9(1-2-13(10)19)20-14-11(16)5-8(3-4-18)6-12(14)17/h1-2,5-7,19H,3-4,18H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



University of California at San Francisco

Curated by ChEMBL


Assay Description
Activity at mouse TAAR1 by measuring cAMP accumulation in HEK293 cells


J Med Chem 49: 1101-12 (2006)


Article DOI: 10.1021/jm0505718
BindingDB Entry DOI: 10.7270/Q2416WNR
More data for this
Ligand-Target Pair