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2 similar compounds to monomer 50186270

Compile data set for download or QSAR
Wt: 330.5
BDBM50186278
Wt: 316.4
BDBM50186309

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50186278,50186309   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50186278
PNG
(2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-...)
Show SMILES CC(C)N1CCCc2cc(OCCCN3CCCCC3)ccc2C1
Show InChI InChI=1S/C21H34N2O/c1-18(2)23-14-6-8-19-16-21(10-9-20(19)17-23)24-15-7-13-22-11-4-3-5-12-22/h9-10,16,18H,3-8,11-15,17H2,1-2H3
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UniProtKB/SwissProt

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PC sid
UniChem

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Similars

Article
PubMed
0.200n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor


Bioorg Med Chem Lett 16: 3415-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.004
BindingDB Entry DOI: 10.7270/Q2WM1D07
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50186309
PNG
(2-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...)
Show SMILES CCN1CCCc2cc(OCCCN3CCCCC3)ccc2C1
Show InChI InChI=1S/C20H32N2O/c1-2-21-13-6-8-18-16-20(10-9-19(18)17-21)23-15-7-14-22-11-4-3-5-12-22/h9-10,16H,2-8,11-15,17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.340n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor


Bioorg Med Chem Lett 16: 3415-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.004
BindingDB Entry DOI: 10.7270/Q2WM1D07
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50186309
PNG
(2-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...)
Show SMILES CCN1CCCc2cc(OCCCN3CCCCC3)ccc2C1
Show InChI InChI=1S/C20H32N2O/c1-2-21-13-6-8-18-16-20(10-9-19(18)17-21)23-15-7-14-22-11-4-3-5-12-22/h9-10,16H,2-8,11-15,17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.560n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor


Bioorg Med Chem Lett 16: 3415-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.004
BindingDB Entry DOI: 10.7270/Q2WM1D07
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50186278
PNG
(2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-...)
Show SMILES CC(C)N1CCCc2cc(OCCCN3CCCCC3)ccc2C1
Show InChI InChI=1S/C21H34N2O/c1-18(2)23-14-6-8-19-16-21(10-9-20(19)17-23)24-15-7-13-22-11-4-3-5-12-22/h9-10,16,18H,3-8,11-15,17H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
1.29n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor


Bioorg Med Chem Lett 16: 3415-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.004
BindingDB Entry DOI: 10.7270/Q2WM1D07
More data for this
Ligand-Target Pair