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1 similar compounds to monomer 50093791

Compile data set for download or QSAR
Wt: 386.5
BDBM50190759

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190759   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neprilysin


(Homo sapiens (Human))
BDBM50190759
PNG
(2-((1-(((R)-1-benzylpyrrolidin-3-yl)carbamoyl)cycl...)
Show SMILES CCCC(CC1(CCCC1)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1)C(O)=O
Show InChI InChI=1S/C23H34N2O3/c1-2-8-19(21(26)27)15-23(12-6-7-13-23)22(28)24-20-11-14-25(17-20)16-18-9-4-3-5-10-18/h3-5,9-10,19-20H,2,6-8,11-17H2,1H3,(H,24,28)(H,26,27)/t19?,20-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.06E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Cholinesterases


(Homo sapiens (Human))
BDBM50190759
PNG
(2-((1-(((R)-1-benzylpyrrolidin-3-yl)carbamoyl)cycl...)
Show SMILES CCCC(CC1(CCCC1)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1)C(O)=O
Show InChI InChI=1S/C23H34N2O3/c1-2-8-19(21(26)27)15-23(12-6-7-13-23)22(28)24-20-11-14-25(17-20)16-18-9-4-3-5-10-18/h3-5,9-10,19-20H,2,6-8,11-17H2,1H3,(H,24,28)(H,26,27)/t19?,20-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog ACE


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair