BindingDB logo
myBDB logout

12 similar compounds to monomer 50272567

Compile data set for download or QSAR
Wt: 407.4
BDBM50195511
Wt: 389.4
BDBM50195514
Wt: 413.8
BDBM50195515
Wt: 407.4
BDBM50195516
Wt: 407.4
BDBM50195518
Wt: 375.4
BDBM50195519
Wt: 361.4
BDBM50195520
Wt: 405.4
BDBM50195523
Wt: 407.4
BDBM50195527
Wt: 389.4
BDBM50195528
Wt: 379.4
BDBM50195529
Wt: 369.5
BDBM50335940

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50195511,50195514,50195515,50195516,50195518,50195519,50195520,50195523,50195527,50195528,50195529,50335940   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(MOUSE)
BDBM50195527
PNG
(CHEMBL387001 | N-cycloheptyl-1-(p-fluorobenzyl)-7-...)
Show SMILES Cc1ccc2c(n1)n(Cc1ccc(F)cc1)cc(C(=O)NC1CCCCCC1)c2=O
Show InChI InChI=1S/C24H26FN3O2/c1-16-8-13-20-22(29)21(24(30)27-19-6-4-2-3-5-7-19)15-28(23(20)26-16)14-17-9-11-18(25)12-10-17/h8-13,15,19H,2-7,14H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50195516
PNG
(CHEMBL216382 | N-(4'-methylcyclohexyl)-1-(p-fluoro...)
Show SMILES CC1CCC(CC1)NC(=O)c1cn(Cc2ccc(F)cc2)c2nc(C)ccc2c1=O
Show InChI InChI=1S/C24H26FN3O2/c1-15-3-10-19(11-4-15)27-24(30)21-14-28(13-17-6-8-18(25)9-7-17)23-20(22(21)29)12-5-16(2)26-23/h5-9,12,14-15,19H,3-4,10-11,13H2,1-2H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.40n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195527
PNG
(CHEMBL387001 | N-cycloheptyl-1-(p-fluorobenzyl)-7-...)
Show SMILES Cc1ccc2c(n1)n(Cc1ccc(F)cc1)cc(C(=O)NC1CCCCCC1)c2=O
Show InChI InChI=1S/C24H26FN3O2/c1-16-8-13-20-22(29)21(24(30)27-19-6-4-2-3-5-7-19)15-28(23(20)26-16)14-17-9-11-18(25)12-10-17/h8-13,15,19H,2-7,14H2,1H3,(H,27,30)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.30n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50195514
PNG
(CHEMBL217266 | N-cycloheptyl-1-benzyl-7-methyl-1,8...)
Show SMILES Cc1ccc2c(n1)n(Cc1ccccc1)cc(C(=O)NC1CCCCCC1)c2=O
Show InChI InChI=1S/C24H27N3O2/c1-17-13-14-20-22(28)21(24(29)26-19-11-7-2-3-8-12-19)16-27(23(20)25-17)15-18-9-5-4-6-10-18/h4-6,9-10,13-14,16,19H,2-3,7-8,11-12,15H2,1H3,(H,26,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.10n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50335940
PNG
(CHEMBL1668521 | N-cyclohexyl-1-hexyl-7-methyl-4-ox...)
Show SMILES CCCCCCn1cc(C(=O)NC2CCCCC2)c(=O)c2ccc(C)nc12
Show InChI InChI=1S/C22H31N3O2/c1-3-4-5-9-14-25-15-19(22(27)24-17-10-7-6-8-11-17)20(26)18-13-12-16(2)23-21(18)25/h12-13,15,17H,3-11,14H2,1-2H3,(H,24,27)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Displacement of [3H]CP 55940 from human CB2 receptor in cell free system


Eur J Med Chem 46: 547-55 (2011)


Article DOI: 10.1016/j.ejmech.2010.11.034
BindingDB Entry DOI: 10.7270/Q2CF9QCJ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50195511
PNG
(CHEMBL217549 | N-(4'-methylcyclohexyl)-1-(o-fluoro...)
Show SMILES CC1CCC(CC1)NC(=O)c1cn(Cc2ccccc2F)c2nc(C)ccc2c1=O
Show InChI InChI=1S/C24H26FN3O2/c1-15-7-10-18(11-8-15)27-24(30)20-14-28(13-17-5-3-4-6-21(17)25)23-19(22(20)29)12-9-16(2)26-23/h3-6,9,12,14-15,18H,7-8,10-11,13H2,1-2H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
8.40n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195516
PNG
(CHEMBL216382 | N-(4'-methylcyclohexyl)-1-(p-fluoro...)
Show SMILES CC1CCC(CC1)NC(=O)c1cn(Cc2ccc(F)cc2)c2nc(C)ccc2c1=O
Show InChI InChI=1S/C24H26FN3O2/c1-15-3-10-19(11-4-15)27-24(30)21-14-28(13-17-6-8-18(25)9-7-17)23-20(22(21)29)12-5-16(2)26-23/h5-9,12,14-15,19H,3-4,10-11,13H2,1-2H3,(H,27,30)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
8.70n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50195519
PNG
(CHEMBL384595 | N-cyclohexyl-7-methyl-1-benzyl-1,8-...)
Show SMILES Cc1ccc2c(n1)n(Cc1ccccc1)cc(C(=O)NC1CCCCC1)c2=O
Show InChI InChI=1S/C23H25N3O2/c1-16-12-13-19-21(27)20(23(28)25-18-10-6-3-7-11-18)15-26(22(19)24-16)14-17-8-4-2-5-9-17/h2,4-5,8-9,12-13,15,18H,3,6-7,10-11,14H2,1H3,(H,25,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
10n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50195529
PNG
(CHEMBL386489 | N-cyclohexyl-1-(p-fluorbenzyl)-1,8-...)
Show SMILES Fc1ccc(Cn2cc(C(=O)NC3CCCCC3)c(=O)c3cccnc23)cc1
Show InChI InChI=1S/C22H22FN3O2/c23-16-10-8-15(9-11-16)13-26-14-19(20(27)18-7-4-12-24-21(18)26)22(28)25-17-5-2-1-3-6-17/h4,7-12,14,17H,1-3,5-6,13H2,(H,25,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
13n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50195518
PNG
(CHEMBL216057 | N-cycloheptyl-1-(o-fluorbenzyl)-7-m...)
Show SMILES Cc1ccc2c(n1)n(Cc1ccccc1F)cc(C(=O)NC1CCCCCC1)c2=O
Show InChI InChI=1S/C24H26FN3O2/c1-16-12-13-19-22(29)20(24(30)27-18-9-4-2-3-5-10-18)15-28(23(19)26-16)14-17-8-6-7-11-21(17)25/h6-8,11-13,15,18H,2-5,9-10,14H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
13.4n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50195528
PNG
(CHEMBL218295 | N-cyclohexyl-7-methyl-1-phenethyl-1...)
Show SMILES Cc1ccc2c(n1)n(CCc1ccccc1)cc(C(=O)NC1CCCCC1)c2=O
Show InChI InChI=1S/C24H27N3O2/c1-17-12-13-20-22(28)21(24(29)26-19-10-6-3-7-11-19)16-27(23(20)25-17)15-14-18-8-4-2-5-9-18/h2,4-5,8-9,12-13,16,19H,3,6-7,10-11,14-15H2,1H3,(H,26,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
16.3n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50195515
PNG
(CHEMBL217583 | N-cyclohexyl-7-chloro-1-(p-fluorben...)
Show SMILES Fc1ccc(Cn2cc(C(=O)NC3CCCCC3)c(=O)c3ccc(Cl)nc23)cc1
Show InChI InChI=1S/C22H21ClFN3O2/c23-19-11-10-17-20(28)18(22(29)25-16-4-2-1-3-5-16)13-27(21(17)26-19)12-14-6-8-15(24)9-7-14/h6-11,13,16H,1-5,12H2,(H,25,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
21.4n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50195523
PNG
(CHEMBL216067 | N-cyclohexyl-7-methyl-1-(4-methoxyb...)
Show SMILES COc1ccc(Cn2cc(C(=O)NC3CCCCC3)c(=O)c3ccc(C)nc23)cc1
Show InChI InChI=1S/C24H27N3O3/c1-16-8-13-20-22(28)21(24(29)26-18-6-4-3-5-7-18)15-27(23(20)25-16)14-17-9-11-19(30-2)12-10-17/h8-13,15,18H,3-7,14H2,1-2H3,(H,26,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
35.8n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195511
PNG
(CHEMBL217549 | N-(4'-methylcyclohexyl)-1-(o-fluoro...)
Show SMILES CC1CCC(CC1)NC(=O)c1cn(Cc2ccccc2F)c2nc(C)ccc2c1=O
Show InChI InChI=1S/C24H26FN3O2/c1-15-7-10-18(11-8-15)27-24(30)20-14-28(13-17-5-3-4-6-21(17)25)23-19(22(20)29)12-9-16(2)26-23/h3-6,9,12,14-15,18H,7-8,10-11,13H2,1-2H3,(H,27,30)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
37.5n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50195520
PNG
(CHEMBL214511 | N-cyclohexyl-1-benzyl-1,8-naphthyri...)
Show SMILES O=C(NC1CCCCC1)c1cn(Cc2ccccc2)c2ncccc2c1=O
Show InChI InChI=1S/C22H23N3O2/c26-20-18-12-7-13-23-21(18)25(14-16-8-3-1-4-9-16)15-19(20)22(27)24-17-10-5-2-6-11-17/h1,3-4,7-9,12-13,15,17H,2,5-6,10-11,14H2,(H,24,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
48.6n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50335940
PNG
(CHEMBL1668521 | N-cyclohexyl-1-hexyl-7-methyl-4-ox...)
Show SMILES CCCCCCn1cc(C(=O)NC2CCCCC2)c(=O)c2ccc(C)nc12
Show InChI InChI=1S/C22H31N3O2/c1-3-4-5-9-14-25-15-19(22(27)24-17-10-7-6-8-11-17)20(26)18-13-12-16(2)23-21(18)25/h12-13,15,17H,3-11,14H2,1-2H3,(H,24,27)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
95n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Displacement of [3H]CP 55940 from human CB1 receptor in cell free system


Eur J Med Chem 46: 547-55 (2011)


Article DOI: 10.1016/j.ejmech.2010.11.034
BindingDB Entry DOI: 10.7270/Q2CF9QCJ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195519
PNG
(CHEMBL384595 | N-cyclohexyl-7-methyl-1-benzyl-1,8-...)
Show SMILES Cc1ccc2c(n1)n(Cc1ccccc1)cc(C(=O)NC1CCCCC1)c2=O
Show InChI InChI=1S/C23H25N3O2/c1-16-12-13-19-21(27)20(23(28)25-18-10-6-3-7-11-18)15-26(22(19)24-16)14-17-8-4-2-5-9-17/h2,4-5,8-9,12-13,15,18H,3,6-7,10-11,14H2,1H3,(H,25,28)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
127n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195514
PNG
(CHEMBL217266 | N-cycloheptyl-1-benzyl-7-methyl-1,8...)
Show SMILES Cc1ccc2c(n1)n(Cc1ccccc1)cc(C(=O)NC1CCCCCC1)c2=O
Show InChI InChI=1S/C24H27N3O2/c1-17-13-14-20-22(28)21(24(29)26-19-11-7-2-3-8-12-19)16-27(23(20)25-17)15-18-9-5-4-6-10-18/h4-6,9-10,13-14,16,19H,2-3,7-8,11-12,15H2,1H3,(H,26,29)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
143n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195518
PNG
(CHEMBL216057 | N-cycloheptyl-1-(o-fluorbenzyl)-7-m...)
Show SMILES Cc1ccc2c(n1)n(Cc1ccccc1F)cc(C(=O)NC1CCCCCC1)c2=O
Show InChI InChI=1S/C24H26FN3O2/c1-16-12-13-19-22(29)20(24(30)27-18-9-4-2-3-5-10-18)15-28(23(19)26-16)14-17-8-6-7-11-21(17)25/h6-8,11-13,15,18H,2-5,9-10,14H2,1H3,(H,27,30)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
149n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195529
PNG
(CHEMBL386489 | N-cyclohexyl-1-(p-fluorbenzyl)-1,8-...)
Show SMILES Fc1ccc(Cn2cc(C(=O)NC3CCCCC3)c(=O)c3cccnc23)cc1
Show InChI InChI=1S/C22H22FN3O2/c23-16-10-8-15(9-11-16)13-26-14-19(20(27)18-7-4-12-24-21(18)26)22(28)25-17-5-2-1-3-6-17/h4,7-12,14,17H,1-3,5-6,13H2,(H,25,28)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
384n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195515
PNG
(CHEMBL217583 | N-cyclohexyl-7-chloro-1-(p-fluorben...)
Show SMILES Fc1ccc(Cn2cc(C(=O)NC3CCCCC3)c(=O)c3ccc(Cl)nc23)cc1
Show InChI InChI=1S/C22H21ClFN3O2/c23-19-11-10-17-20(28)18(22(29)25-16-4-2-1-3-5-16)13-27(21(17)26-19)12-14-6-8-15(24)9-7-14/h6-11,13,16H,1-5,12H2,(H,25,29)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
495n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195523
PNG
(CHEMBL216067 | N-cyclohexyl-7-methyl-1-(4-methoxyb...)
Show SMILES COc1ccc(Cn2cc(C(=O)NC3CCCCC3)c(=O)c3ccc(C)nc23)cc1
Show InChI InChI=1S/C24H27N3O3/c1-16-8-13-20-22(28)21(24(29)26-18-6-4-3-5-7-18)15-27(23(20)25-16)14-17-9-11-19(30-2)12-10-17/h8-13,15,18H,3-7,14H2,1-2H3,(H,26,29)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195520
PNG
(CHEMBL214511 | N-cyclohexyl-1-benzyl-1,8-naphthyri...)
Show SMILES O=C(NC1CCCCC1)c1cn(Cc2ccccc2)c2ncccc2c1=O
Show InChI InChI=1S/C22H23N3O2/c26-20-18-12-7-13-23-21(18)25(14-16-8-3-1-4-9-16)15-19(20)22(27)24-17-10-5-2-6-11-17/h1,3-4,7-9,12-13,15,17H,2,5-6,10-11,14H2,(H,24,27)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195528
PNG
(CHEMBL218295 | N-cyclohexyl-7-methyl-1-phenethyl-1...)
Show SMILES Cc1ccc2c(n1)n(CCc1ccccc1)cc(C(=O)NC1CCCCC1)c2=O
Show InChI InChI=1S/C24H27N3O2/c1-17-12-13-20-22(28)21(24(29)26-19-10-6-3-7-11-19)16-27(23(20)25-17)15-14-18-8-4-2-5-9-18/h2,4-5,8-9,12-13,16,19H,3,6-7,10-11,14-15H2,1H3,(H,26,29)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195511
PNG
(CHEMBL217549 | N-(4'-methylcyclohexyl)-1-(o-fluoro...)
Show SMILES CC1CCC(CC1)NC(=O)c1cn(Cc2ccccc2F)c2nc(C)ccc2c1=O
Show InChI InChI=1S/C24H26FN3O2/c1-15-7-10-18(11-8-15)27-24(30)20-14-28(13-17-5-3-4-6-21(17)25)23-19(22(20)29)12-9-16(2)26-23/h3-6,9,12,14-15,18H,7-8,10-11,13H2,1-2H3,(H,27,30)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 138n/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Activity at CB1 receptor assessed as stimulation of [35S]GTP-gamma-S binding in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195516
PNG
(CHEMBL216382 | N-(4'-methylcyclohexyl)-1-(p-fluoro...)
Show SMILES CC1CCC(CC1)NC(=O)c1cn(Cc2ccc(F)cc2)c2nc(C)ccc2c1=O
Show InChI InChI=1S/C24H26FN3O2/c1-15-3-10-19(11-4-15)27-24(30)21-14-28(13-17-6-8-18(25)9-7-17)23-20(22(21)29)12-5-16(2)26-23/h5-9,12,14-15,19H,3-4,10-11,13H2,1-2H3,(H,27,30)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 27n/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Activity at CB1 receptor assessed as stimulation of [35S]GTP-gamma-S binding in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair