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11 similar compounds to monomer 50200642

Compile data set for download or QSAR
Wt: 358.4
BDBM50200629
Wt: 342.4
BDBM50200632
Wt: 354.4
BDBM50200634
Wt: 354.4
BDBM50200637
Wt: 356.4
BDBM50200639
Wt: 356.4
BDBM50200640
Wt: 340.4
BDBM50200641
Wt: 382.5
BDBM50200643
Wt: 326.4
BDBM50200644
Wt: 368.5
BDBM50200645
Wt: 340.4
BDBM50200647

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50200629,50200632,50200634,50200637,50200639,50200640,50200641,50200643,50200644,50200645,50200647   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50200641
PNG
(4-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)naphthalen-...)
Show SMILES CC1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H24N2/c1-18-3-2-13-26(18)14-12-19-4-9-24-16-23(11-10-22(24)15-19)21-7-5-20(17-25)6-8-21/h4-11,15-16,18H,2-3,12-14H2,1H3
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0.180n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50200647
PNG
((R)-4-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)naphtha...)
Show SMILES C[C@@H]1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H24N2/c1-18-3-2-13-26(18)14-12-19-4-9-24-16-23(11-10-22(24)15-19)21-7-5-20(17-25)6-8-21/h4-11,15-16,18H,2-3,12-14H2,1H3/t18-/m1/s1
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0.240n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50200647
PNG
((R)-4-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)naphtha...)
Show SMILES C[C@@H]1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H24N2/c1-18-3-2-13-26(18)14-12-19-4-9-24-16-23(11-10-22(24)15-19)21-7-5-20(17-25)6-8-21/h4-11,15-16,18H,2-3,12-14H2,1H3/t18-/m1/s1
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0.240n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to human histamine H3 receptor


J Med Chem 54: 26-53 (2011)


Article DOI: 10.1021/jm100064d
BindingDB Entry DOI: 10.7270/Q2VQ33RV
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50200639
PNG
((S)-4-(6-(2-(2-(hydroxymethyl)pyrrolidin-1-yl)ethy...)
Show SMILES OC[C@@H]1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H24N2O/c25-16-19-4-6-20(7-5-19)22-10-9-21-14-18(3-8-23(21)15-22)11-13-26-12-1-2-24(26)17-27/h3-10,14-15,24,27H,1-2,11-13,17H2/t24-/m0/s1
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0.440n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50200644
PNG
(4-(6-(2-(pyrrolidin-1-yl)ethyl)naphthalen-2-yl)ben...)
Show SMILES N#Cc1ccc(cc1)-c1ccc2cc(CCN3CCCC3)ccc2c1
Show InChI InChI=1S/C23H22N2/c24-17-19-4-6-20(7-5-19)22-10-9-21-15-18(3-8-23(21)16-22)11-14-25-12-1-2-13-25/h3-10,15-16H,1-2,11-14H2
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0.490n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50200629
PNG
((S)-4-(6-(2-(2-(fluoromethyl)pyrrolidin-1-yl)ethyl...)
Show SMILES FC[C@@H]1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H23FN2/c25-16-24-2-1-12-27(24)13-11-18-3-8-23-15-22(10-9-21(23)14-18)20-6-4-19(17-26)5-7-20/h3-10,14-15,24H,1-2,11-13,16H2/t24-/m0/s1
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0.810n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50200641
PNG
(4-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)naphthalen-...)
Show SMILES CC1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H24N2/c1-18-3-2-13-26(18)14-12-19-4-9-24-16-23(11-10-22(24)15-19)21-7-5-20(17-25)6-8-21/h4-11,15-16,18H,2-3,12-14H2,1H3
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1.24n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50200647
PNG
((R)-4-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)naphtha...)
Show SMILES C[C@@H]1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H24N2/c1-18-3-2-13-26(18)14-12-19-4-9-24-16-23(11-10-22(24)15-19)21-7-5-20(17-25)6-8-21/h4-11,15-16,18H,2-3,12-14H2,1H3/t18-/m1/s1
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2.48n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50200647
PNG
((R)-4-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)naphtha...)
Show SMILES C[C@@H]1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H24N2/c1-18-3-2-13-26(18)14-12-19-4-9-24-16-23(11-10-22(24)15-19)21-7-5-20(17-25)6-8-21/h4-11,15-16,18H,2-3,12-14H2,1H3/t18-/m1/s1
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2.5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to rat cortical histamine H3 receptor


J Med Chem 54: 26-53 (2011)


Article DOI: 10.1021/jm100064d
BindingDB Entry DOI: 10.7270/Q2VQ33RV
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50200640
PNG
((R)-4-(6-(2-(2-(hydroxymethyl)pyrrolidin-1-yl)ethy...)
Show SMILES OC[C@H]1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H24N2O/c25-16-19-4-6-20(7-5-19)22-10-9-21-14-18(3-8-23(21)15-22)11-13-26-12-1-2-24(26)17-27/h3-10,14-15,24,27H,1-2,11-13,17H2/t24-/m1/s1
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2.89n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50200632
PNG
(4-(6-(2-(ethyl(isopropyl)amino)ethyl)naphthalen-2-...)
Show SMILES CCN(CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N)C(C)C
Show InChI InChI=1S/C24H26N2/c1-4-26(18(2)3)14-13-19-5-10-24-16-23(12-11-22(24)15-19)21-8-6-20(17-25)7-9-21/h5-12,15-16,18H,4,13-14H2,1-3H3
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4.62n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50200644
PNG
(4-(6-(2-(pyrrolidin-1-yl)ethyl)naphthalen-2-yl)ben...)
Show SMILES N#Cc1ccc(cc1)-c1ccc2cc(CCN3CCCC3)ccc2c1
Show InChI InChI=1S/C23H22N2/c24-17-19-4-6-20(7-5-19)22-10-9-21-15-18(3-8-23(21)16-22)11-14-25-12-1-2-13-25/h3-10,15-16H,1-2,11-14H2
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6.42n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50200634
PNG
((R)-4-(6-(2-(2-ethylpyrrolidin-1-yl)ethyl)naphthal...)
Show SMILES CC[C@@H]1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C25H26N2/c1-2-25-4-3-14-27(25)15-13-19-5-10-24-17-23(12-11-22(24)16-19)21-8-6-20(18-26)7-9-21/h5-12,16-17,25H,2-4,13-15H2,1H3/t25-/m1/s1
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8.61n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50200637
PNG
((R)-4-(6-(2-(2-methylpiperidin-1-yl)ethyl)naphthal...)
Show SMILES C[C@@H]1CCCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C25H26N2/c1-19-4-2-3-14-27(19)15-13-20-5-10-25-17-24(12-11-23(25)16-20)22-8-6-21(18-26)7-9-22/h5-12,16-17,19H,2-4,13-15H2,1H3/t19-/m1/s1
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8.71n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50200629
PNG
((S)-4-(6-(2-(2-(fluoromethyl)pyrrolidin-1-yl)ethyl...)
Show SMILES FC[C@@H]1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H23FN2/c25-16-24-2-1-12-27(24)13-11-18-3-8-23-15-22(10-9-21(23)14-18)20-6-4-19(17-26)5-7-20/h3-10,14-15,24H,1-2,11-13,16H2/t24-/m0/s1
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9.77n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50200639
PNG
((S)-4-(6-(2-(2-(hydroxymethyl)pyrrolidin-1-yl)ethy...)
Show SMILES OC[C@@H]1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H24N2O/c25-16-19-4-6-20(7-5-19)22-10-9-21-14-18(3-8-23(21)15-22)11-13-26-12-1-2-24(26)17-27/h3-10,14-15,24,27H,1-2,11-13,17H2/t24-/m0/s1
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11n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50200645
PNG
(4-(6-(2-(2-isopropylpyrrolidin-1-yl)ethyl)naphthal...)
Show SMILES CC(C)C1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C26H28N2/c1-19(2)26-4-3-14-28(26)15-13-20-5-10-25-17-24(12-11-23(25)16-20)22-8-6-21(18-27)7-9-22/h5-12,16-17,19,26H,3-4,13-15H2,1-2H3
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27.3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50200632
PNG
(4-(6-(2-(ethyl(isopropyl)amino)ethyl)naphthalen-2-...)
Show SMILES CCN(CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N)C(C)C
Show InChI InChI=1S/C24H26N2/c1-4-26(18(2)3)14-13-19-5-10-24-16-23(12-11-22(24)15-19)21-8-6-20(17-25)7-9-21/h5-12,15-16,18H,4,13-14H2,1-3H3
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30.3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50200634
PNG
((R)-4-(6-(2-(2-ethylpyrrolidin-1-yl)ethyl)naphthal...)
Show SMILES CC[C@@H]1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C25H26N2/c1-2-25-4-3-14-27(25)15-13-19-5-10-24-17-23(12-11-22(24)16-19)21-8-6-20(18-26)7-9-21/h5-12,16-17,25H,2-4,13-15H2,1H3/t25-/m1/s1
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33.7n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50200640
PNG
((R)-4-(6-(2-(2-(hydroxymethyl)pyrrolidin-1-yl)ethy...)
Show SMILES OC[C@H]1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H24N2O/c25-16-19-4-6-20(7-5-19)22-10-9-21-14-18(3-8-23(21)15-22)11-13-26-12-1-2-24(26)17-27/h3-10,14-15,24,27H,1-2,11-13,17H2/t24-/m1/s1
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42.8n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50200637
PNG
((R)-4-(6-(2-(2-methylpiperidin-1-yl)ethyl)naphthal...)
Show SMILES C[C@@H]1CCCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C25H26N2/c1-19-4-2-3-14-27(19)15-13-20-5-10-25-17-24(12-11-23(25)16-20)22-8-6-21(18-26)7-9-22/h5-12,16-17,19H,2-4,13-15H2,1H3/t19-/m1/s1
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141n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50200645
PNG
(4-(6-(2-(2-isopropylpyrrolidin-1-yl)ethyl)naphthal...)
Show SMILES CC(C)C1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C26H28N2/c1-19(2)26-4-3-14-28(26)15-13-20-5-10-25-17-24(12-11-23(25)16-20)22-8-6-21(18-27)7-9-22/h5-12,16-17,19,26H,3-4,13-15H2,1-2H3
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233n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50200643
PNG
(4-(6-(2-(2-isobutylpyrrolidin-1-yl)ethyl)naphthale...)
Show SMILES CC(C)CC1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C27H30N2/c1-20(2)16-27-4-3-14-29(27)15-13-21-5-10-26-18-25(12-11-24(26)17-21)23-8-6-22(19-28)7-9-23/h5-12,17-18,20,27H,3-4,13-16H2,1-2H3
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273n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50200643
PNG
(4-(6-(2-(2-isobutylpyrrolidin-1-yl)ethyl)naphthale...)
Show SMILES CC(C)CC1CCCN1CCc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C27H30N2/c1-20(2)16-27-4-3-14-29(27)15-13-21-5-10-26-18-25(12-11-24(26)17-21)23-8-6-22(19-28)7-9-23/h5-12,17-18,20,27H,3-4,13-16H2,1-2H3
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465n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 17: 1443-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.073
BindingDB Entry DOI: 10.7270/Q2416WR3
More data for this
Ligand-Target Pair