Compounds in cluster

19 similar compounds to monomer 50233990

Wt: 392.4 BDBM50204485	Wt: 378.4 BDBM50204516	Wt: 398.4 BDBM50233957	Wt: 513.6 BDBM50234023	Wt: 304.6 BDBM50234016
Wt: 309.3 BDBM50234024	Wt: 485.8 BDBM50233991	Wt: 1078.1 BDBM50233955	Wt: 567.5 BDBM50233986	Wt: 562.9 BDBM50233995
Wt: 483.5 BDBM50233958	Wt: 576.9 BDBM50233994	Wt: 321.5 BDBM50233996	Wt: 428.3 BDBM50234014	Wt: 640.0 BDBM50233992

Displayed 1 to 15 (of 19 total ) | Next | Last >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 44 hits for monomerid = 50204485,50204516,50233957,50234023,50234016,50234024,50233991,50233955,50233986,50233995,50233958,50233994,50233996,50234014,50233992
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50204485 (CHEMBL219880 \| methyl 6-(2-(7-phenylheptanoyl)oxaz...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	9.0	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204485 (CHEMBL219880 \| methyl 6-(2-(7-phenylheptanoyl)oxaz...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204485 (CHEMBL219880 \| methyl 6-(2-(7-phenylheptanoyl)oxaz...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	9.0	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH (unknown origin) at pH 9				Bioorg Med Chem Lett 18: 5847-50 (2008) Article DOI: 10.1016/j.bmcl.2008.06.086 BindingDB Entry DOI: 10.7270/Q2GF0TBV
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	10.3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 7.4				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	10.4	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH (unknown origin) at pH 7.5				Bioorg Med Chem Lett 18: 5847-50 (2008) Article DOI: 10.1016/j.bmcl.2008.06.086 BindingDB Entry DOI: 10.7270/Q2GF0TBV
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	14.5	n/a	n/a	n/a	n/a	n/a	n/a	8.0	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 8.0				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	9.0	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH (unknown origin) at pH 9				Bioorg Med Chem Lett 18: 5847-50 (2008) Article DOI: 10.1016/j.bmcl.2008.06.086 BindingDB Entry DOI: 10.7270/Q2GF0TBV
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of rat FAAH expressed in Escherichia coli				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50233957 (6-(2-(3-(biphenyl-4-yl)propanoyl)oxazol-5-yl)picol...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	9.0	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH (unknown origin) at pH 9				Bioorg Med Chem Lett 18: 5847-50 (2008) Article DOI: 10.1016/j.bmcl.2008.06.086 BindingDB Entry DOI: 10.7270/Q2GF0TBV
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50233957 (6-(2-(3-(biphenyl-4-yl)propanoyl)oxazol-5-yl)picol...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH expressed in african green monkey COS7 cells				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human FAAH expressed in COS7 cells by [14C]oleamide breakdown				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50234023 (6-(2-(3-(4'-(thiomorpholinomethyl)biphenyl-4-yl)pr...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	9.0	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH (unknown origin) at pH 9				Bioorg Med Chem Lett 18: 5847-50 (2008) Article DOI: 10.1016/j.bmcl.2008.06.086 BindingDB Entry DOI: 10.7270/Q2GF0TBV
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50234023 (6-(2-(3-(4'-(thiomorpholinomethyl)biphenyl-4-yl)pr...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
ITGA5/ITGB1 (Homo sapiens (Human))	BDBM50233955 (CHEMBL4095441) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of biotinylated fibronectin from recombinant human integrin alpha5beta1 dark incubated for 3 hrs by solid-phase receptor binding assay				J Med Chem 60: 248-262 (2017) Article DOI: 10.1021/acs.jmedchem.6b01266 BindingDB Entry DOI: 10.7270/Q2CC12ZK
Universit£ degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
ITGAV/ITGB3 (Homo sapiens (Human))	BDBM50233955 (CHEMBL4095441) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of biotinylated vitronectin from recombinant human integrin alphaVbeta3 dark incubated for 3 hrs by solid-phase receptor binding assay				J Med Chem 60: 248-262 (2017) Article DOI: 10.1021/acs.jmedchem.6b01266 BindingDB Entry DOI: 10.7270/Q2CC12ZK
Universit£ degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
ITGA5/ITGB1 (Homo sapiens (Human))	BDBM50233958 (CHEMBL4087743) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of alpha5beta1 (unknown origin)				J Med Chem 60: 248-262 (2017) Article DOI: 10.1021/acs.jmedchem.6b01266 BindingDB Entry DOI: 10.7270/Q2CC12ZK
Universit£ degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
ITGAV/ITGB5 (Homo sapiens (Human))	BDBM50233958 (CHEMBL4087743) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of biotinylated vitronectin from human integrin alphaVbeta5 measured after 3 hrs by solid-phase receptor binding assay				J Med Chem 60: 248-262 (2017) Article DOI: 10.1021/acs.jmedchem.6b01266 BindingDB Entry DOI: 10.7270/Q2CC12ZK
Universit£ degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
ITGAV/ITGB3 (Homo sapiens (Human))	BDBM50233958 (CHEMBL4087743) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of biotinylated vitronectin from human integrin alphaVbeta3 measured after 3 hrs by solid-phase receptor binding assay				J Med Chem 60: 248-262 (2017) Article DOI: 10.1021/acs.jmedchem.6b01266 BindingDB Entry DOI: 10.7270/Q2CC12ZK
Universit£ degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Dynamin-2 (Homo sapiens (Human))	BDBM50233996 (CHEMBL4073407) Show SMILES CCCCCCCCCCNc1ccnc(NCCN(C)C)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...				J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T
The University of Newcastle Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234014 (CHEMBL4072039) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234016 (CHEMBL4093300) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Microtubule-associated protein 2 (Homo sapiens (Human))	BDBM50234024 (CHEMBL4097198) Show SMILES Cc1ccccc1OC[C@H]1CCCN1c1ncnc2[nH]cnc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His tagged MetAP-2 using tripeptide Met-Ala-Ser as substrate preincubated for 15 mins followed by substrat...				Bioorg Med Chem Lett 27: 551-556 (2017) Article DOI: 10.1016/j.bmcl.2016.12.019 BindingDB Entry DOI: 10.7270/Q2V98BB4
Merck KGaA Curated by ChEMBL					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50233986 (CHEMBL4092679) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Karos Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				Bioorg Med Chem Lett 27: 413-419 (2017) Article DOI: 10.1016/j.bmcl.2016.12.053 BindingDB Entry DOI: 10.7270/Q21V5H7S
Karos Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50233991 (CHEMBL4060643) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Karos Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				Bioorg Med Chem Lett 27: 413-419 (2017) Article DOI: 10.1016/j.bmcl.2016.12.053 BindingDB Entry DOI: 10.7270/Q21V5H7S
Karos Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50233992 (CHEMBL4074718) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	885	n/a	n/a	n/a	n/a	n/a	n/a
Karos Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				Bioorg Med Chem Lett 27: 413-419 (2017) Article DOI: 10.1016/j.bmcl.2016.12.053 BindingDB Entry DOI: 10.7270/Q21V5H7S
Karos Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50233994 (CHEMBL4076761) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Karos Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				Bioorg Med Chem Lett 27: 413-419 (2017) Article DOI: 10.1016/j.bmcl.2016.12.053 BindingDB Entry DOI: 10.7270/Q21V5H7S
Karos Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
ITGAV/ITGB3 (Homo sapiens (Human))	BDBM50233955 (CHEMBL4095441) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of vitronectin binding to alphaVbeta3 in human EPC in presence of MnCl2 measured after 30 mins by crystal violet staining based cell adhes...				J Med Chem 60: 248-262 (2017) Article DOI: 10.1021/acs.jmedchem.6b01266 BindingDB Entry DOI: 10.7270/Q2CC12ZK
Universit£ degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human))	BDBM50204485 (CHEMBL219880 \| methyl 6-(2-(7-phenylheptanoyl)oxaz...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of TGH				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50233995 (CHEMBL4091280) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Karos Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				Bioorg Med Chem Lett 27: 413-419 (2017) Article DOI: 10.1016/j.bmcl.2016.12.053 BindingDB Entry DOI: 10.7270/Q21V5H7S
Karos Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Neutral cholesterol ester hydrolase 1 (Homo sapiens (Human))	BDBM50204485 (CHEMBL219880 \| methyl 6-(2-(7-phenylheptanoyl)oxaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of KIAA1363 hydrolase				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair
Neutral cholesterol ester hydrolase 1 (Homo sapiens (Human))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of KIAA1363 hydrolase				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50204485 (CHEMBL219880 \| methyl 6-(2-(7-phenylheptanoyl)oxaz...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of rat FAAH expressed in Escherichia coli				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of TGH				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Neutral cholesterol ester hydrolase 1 (Homo sapiens (Human))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of KIAA1363				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human))	BDBM50233957 (6-(2-(3-(biphenyl-4-yl)propanoyl)oxazol-5-yl)picol...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of TGH				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Neutral cholesterol ester hydrolase 1 (Homo sapiens (Human))	BDBM50233957 (6-(2-(3-(biphenyl-4-yl)propanoyl)oxazol-5-yl)picol...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of KIAA1363				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Neutral cholesterol ester hydrolase 1 (Homo sapiens (Human))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of KIAA1363				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50233957 (6-(2-(3-(biphenyl-4-yl)propanoyl)oxazol-5-yl)picol...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of TGH				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human))	BDBM50204516 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of TGH				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair