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2 similar compounds to monomer 50206660

Compile data set for download or QSAR
Wt: 413.9
BDBM50206644
Wt: 409.5
BDBM50206657

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50206644,50206657   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50206644
PNG
(CHEMBL395545 | N-(1-(3-amino-3-(4-chlorophenyl)pro...)
Show SMILES CCC(=O)N(C1CCN(CC1)C(=O)CC(N)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C23H28ClN3O2/c1-2-22(28)27(19-6-4-3-5-7-19)20-12-14-26(15-13-20)23(29)16-21(25)17-8-10-18(24)11-9-17/h3-11,20-21H,2,12-16,25H2,1H3
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Article
PubMed
990n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Displacement of [3H] DAMGO from rat mu opioid receptor transfected in HN9.10 cells


Bioorg Med Chem Lett 17: 2161-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.114
BindingDB Entry DOI: 10.7270/Q270813K
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50206644
PNG
(CHEMBL395545 | N-(1-(3-amino-3-(4-chlorophenyl)pro...)
Show SMILES CCC(=O)N(C1CCN(CC1)C(=O)CC(N)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C23H28ClN3O2/c1-2-22(28)27(19-6-4-3-5-7-19)20-12-14-26(15-13-20)23(29)16-21(25)17-8-10-18(24)11-9-17/h3-11,20-21H,2,12-16,25H2,1H3
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Article
PubMed
2.40E+3n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from human delta opioid receptor transfected in HN9.10 cells


Bioorg Med Chem Lett 17: 2161-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.114
BindingDB Entry DOI: 10.7270/Q270813K
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50206657
PNG
(CHEMBL230310 | N-(1-(3-amino-3-(4-methoxyphenyl)pr...)
Show SMILES CCC(=O)N(C1CCN(CC1)C(=O)CC(N)c1ccc(OC)cc1)c1ccccc1
Show InChI InChI=1S/C24H31N3O3/c1-3-23(28)27(19-7-5-4-6-8-19)20-13-15-26(16-14-20)24(29)17-22(25)18-9-11-21(30-2)12-10-18/h4-12,20,22H,3,13-17,25H2,1-2H3
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Article
PubMed
9.00E+3n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from human delta opioid receptor transfected in HN9.10 cells


Bioorg Med Chem Lett 17: 2161-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.114
BindingDB Entry DOI: 10.7270/Q270813K
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50206657
PNG
(CHEMBL230310 | N-(1-(3-amino-3-(4-methoxyphenyl)pr...)
Show SMILES CCC(=O)N(C1CCN(CC1)C(=O)CC(N)c1ccc(OC)cc1)c1ccccc1
Show InChI InChI=1S/C24H31N3O3/c1-3-23(28)27(19-7-5-4-6-8-19)20-13-15-26(16-14-20)24(29)17-22(25)18-9-11-21(30-2)12-10-18/h4-12,20,22H,3,13-17,25H2,1-2H3
PDB

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PC sid
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Article
PubMed
9.70E+3n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Displacement of [3H] DAMGO from rat mu opioid receptor transfected in HN9.10 cells


Bioorg Med Chem Lett 17: 2161-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.114
BindingDB Entry DOI: 10.7270/Q270813K
More data for this
Ligand-Target Pair