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4 similar compounds to monomer 50206651

Compile data set for download or QSAR
Wt: 395.4
BDBM50206647
Wt: 413.9
BDBM50206652
Wt: 379.4
BDBM50206655
Wt: 455.5
BDBM50206659

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50206647,50206652,50206655,50206659   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50206659
PNG
((S)-N-(1-(2-amino-3,3-diphenylpropanoyl)piperidin-...)
Show SMILES CCC(=O)N(C1CCN(CC1)C(=O)[C@@H](N)C(c1ccccc1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H33N3O2/c1-2-26(33)32(24-16-10-5-11-17-24)25-18-20-31(21-19-25)29(34)28(30)27(22-12-6-3-7-13-22)23-14-8-4-9-15-23/h3-17,25,27-28H,2,18-21,30H2,1H3/t28-/m0/s1
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400n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Displacement of [3H] DAMGO from rat mu opioid receptor transfected in HN9.10 cells


Bioorg Med Chem Lett 17: 2161-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.114
BindingDB Entry DOI: 10.7270/Q270813K
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50206655
PNG
((S)-N-(1-(2-amino-3-phenylpropanoyl)piperidin-4-yl...)
Show SMILES CCC(=O)N(C1CCN(CC1)C(=O)[C@@H](N)Cc1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H29N3O2/c1-2-22(27)26(19-11-7-4-8-12-19)20-13-15-25(16-14-20)23(28)21(24)17-18-9-5-3-6-10-18/h3-12,20-21H,2,13-17,24H2,1H3/t21-/m0/s1
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3.90E+3n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Displacement of [3H] DAMGO from rat mu opioid receptor transfected in HN9.10 cells


Bioorg Med Chem Lett 17: 2161-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.114
BindingDB Entry DOI: 10.7270/Q270813K
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50206659
PNG
((S)-N-(1-(2-amino-3,3-diphenylpropanoyl)piperidin-...)
Show SMILES CCC(=O)N(C1CCN(CC1)C(=O)[C@@H](N)C(c1ccccc1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H33N3O2/c1-2-26(33)32(24-16-10-5-11-17-24)25-18-20-31(21-19-25)29(34)28(30)27(22-12-6-3-7-13-22)23-14-8-4-9-15-23/h3-17,25,27-28H,2,18-21,30H2,1H3/t28-/m0/s1
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PubMed
6.50E+3n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from human delta opioid receptor transfected in HN9.10 cells


Bioorg Med Chem Lett 17: 2161-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.114
BindingDB Entry DOI: 10.7270/Q270813K
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50206655
PNG
((S)-N-(1-(2-amino-3-phenylpropanoyl)piperidin-4-yl...)
Show SMILES CCC(=O)N(C1CCN(CC1)C(=O)[C@@H](N)Cc1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H29N3O2/c1-2-22(27)26(19-11-7-4-8-12-19)20-13-15-25(16-14-20)23(28)21(24)17-18-9-5-3-6-10-18/h3-12,20-21H,2,13-17,24H2,1H3/t21-/m0/s1
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6.90E+3n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from human delta opioid receptor transfected in HN9.10 cells


Bioorg Med Chem Lett 17: 2161-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.114
BindingDB Entry DOI: 10.7270/Q270813K
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50206652
PNG
((R)-N-(1-(2-amino-3-(4-chlorophenyl)propanoyl)pipe...)
Show SMILES CCC(=O)N(C1CCN(CC1)C(=O)[C@H](N)Cc1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C23H28ClN3O2/c1-2-22(28)27(19-6-4-3-5-7-19)20-12-14-26(15-13-20)23(29)21(25)16-17-8-10-18(24)11-9-17/h3-11,20-21H,2,12-16,25H2,1H3/t21-/m1/s1
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6.90E+3n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Displacement of [3H] DAMGO from rat mu opioid receptor transfected in HN9.10 cells


Bioorg Med Chem Lett 17: 2161-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.114
BindingDB Entry DOI: 10.7270/Q270813K
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50206647
PNG
((S)-N-(1-(2-amino-3-(4-hydroxyphenyl)propanoyl)pip...)
Show SMILES CCC(=O)N(C1CCN(CC1)C(=O)[C@@H](N)Cc1ccc(O)cc1)c1ccccc1
Show InChI InChI=1S/C23H29N3O3/c1-2-22(28)26(18-6-4-3-5-7-18)19-12-14-25(15-13-19)23(29)21(24)16-17-8-10-20(27)11-9-17/h3-11,19,21,27H,2,12-16,24H2,1H3/t21-/m0/s1
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PubMed
7.90E+3n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Displacement of [3H] DAMGO from rat mu opioid receptor transfected in HN9.10 cells


Bioorg Med Chem Lett 17: 2161-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.114
BindingDB Entry DOI: 10.7270/Q270813K
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50206647
PNG
((S)-N-(1-(2-amino-3-(4-hydroxyphenyl)propanoyl)pip...)
Show SMILES CCC(=O)N(C1CCN(CC1)C(=O)[C@@H](N)Cc1ccc(O)cc1)c1ccccc1
Show InChI InChI=1S/C23H29N3O3/c1-2-22(28)26(18-6-4-3-5-7-18)19-12-14-25(15-13-19)23(29)21(24)16-17-8-10-20(27)11-9-17/h3-11,19,21,27H,2,12-16,24H2,1H3/t21-/m0/s1
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Article
PubMed
1.60E+4n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from human delta opioid receptor transfected in HN9.10 cells


Bioorg Med Chem Lett 17: 2161-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.114
BindingDB Entry DOI: 10.7270/Q270813K
More data for this
Ligand-Target Pair