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1 similar compounds to monomer 50230982

Compile data set for download or QSAR
Wt: 506.5
BDBM50230978

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50230978   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50230978
PNG
(CHEMBL4086939)
Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(Cn4cccc4CN(C)C)cc3)c3ccccc3)C(=O)Nc2c1
Show InChI InChI=1S/C31H30N4O3/c1-34(2)20-25-10-7-17-35(25)19-21-11-14-24(15-12-21)32-29(22-8-5-4-6-9-22)28-26-16-13-23(31(37)38-3)18-27(26)33-30(28)36/h4-18,32H,19-20H2,1-3H3,(H,33,36)/b29-28-
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...


Bioorg Med Chem 25: 1778-1786 (2017)


Article DOI: 10.1016/j.bmc.2017.01.039
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50230978
PNG
(CHEMBL4086939)
Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(Cn4cccc4CN(C)C)cc3)c3ccccc3)C(=O)Nc2c1
Show InChI InChI=1S/C31H30N4O3/c1-34(2)20-25-10-7-17-35(25)19-21-11-14-24(15-12-21)32-29(22-8-5-4-6-9-22)28-26-16-13-23(31(37)38-3)18-27(26)33-30(28)36/h4-18,32H,19-20H2,1-3H3,(H,33,36)/b29-28-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 168n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated fo...


Bioorg Med Chem 25: 1778-1786 (2017)


Article DOI: 10.1016/j.bmc.2017.01.039
More data for this
Ligand-Target Pair