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16 similar compounds to monomer 50246577

Compile data set for download or QSAR
Wt: 422.5
BDBM50240946
Wt: 498.5
BDBM50246719
Wt: 462.5
BDBM50246575
Purchase
Wt: 490.6
BDBM50246576
Wt: 478.6
BDBM50246578
Wt: 478.5
BDBM50246596
Wt: 492.6
BDBM50246608
Wt: 506.6
BDBM50246609
Wt: 476.5
BDBM50246612
Wt: 512.5
BDBM50246642
Wt: 536.6
BDBM50246643
Wt: 478.5
BDBM50246644
Wt: 476.6
BDBM50246645
Wt: 484.5
BDBM50247100
Wt: 448.5
BDBM50247101
Displayed 1 to 15 (of 16 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50240946,50246719,50246575,50246576,50246578,50246596,50246608,50246609,50246612,50246642,50246643,50246644,50246645,50247100,50247101   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246575
PNG
(1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-y...)
Show SMILES CN(C)C(=O)[C@@H]1CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C27H34N4O3/c1-19-17-21(25(32)30-15-7-6-10-20-9-4-5-11-23(20)30)13-14-22(19)18-28-27(34)31-16-8-12-24(31)26(33)29(2)3/h4-5,9,11,13-14,17,24H,6-8,10,12,15-16,18H2,1-3H3,(H,28,34)/t24-/m0/s1
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2.00E+3n/an/an/an/an/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Binding affinity to human vasopressin V2 receptor expressed in HEK293 cells by radioligand binding assay


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50246575
PNG
(1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-y...)
Show SMILES CN(C)C(=O)[C@@H]1CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C27H34N4O3/c1-19-17-21(25(32)30-15-7-6-10-20-9-4-5-11-23(20)30)13-14-22(19)18-28-27(34)31-16-8-12-24(31)26(33)29(2)3/h4-5,9,11,13-14,17,24H,6-8,10,12,15-16,18H2,1-3H3,(H,28,34)/t24-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Binding affinity to oxytocin receptor (unknown origin)


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246612
PNG
(1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-y...)
Show SMILES CN(C)C(=O)[C@@H]1CC(=O)CN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C27H32N4O4/c1-18-14-20(25(33)30-13-7-6-9-19-8-4-5-10-23(19)30)11-12-21(18)16-28-27(35)31-17-22(32)15-24(31)26(34)29(2)3/h4-5,8,10-12,14,24H,6-7,9,13,15-17H2,1-3H3,(H,28,35)/t24-/m0/s1
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Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246642
PNG
(4,4-Difluoro-1-(2-methyl-4-(2,3,4,5-tetrahydro-1-b...)
Show SMILES CN(C)C(=O)[C@@H]1CC(CN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12)C(F)F
Show InChI InChI=1S/C28H34F2N4O3/c1-18-14-20(26(35)33-13-7-6-9-19-8-4-5-10-23(19)33)11-12-21(18)16-31-28(37)34-17-22(25(29)30)15-24(34)27(36)32(2)3/h4-5,8,10-12,14,22,24-25H,6-7,9,13,15-17H2,1-3H3,(H,31,37)/t22?,24-/m0/s1
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n/an/an/an/a 50n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246643
PNG
(4,4-Dimethoxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1-...)
Show SMILES COC(OC)C1C[C@H](N(C1)C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12)C(=O)N(C)C
Show InChI InChI=1S/C30H40N4O5/c1-20-16-22(27(35)33-15-9-8-11-21-10-6-7-12-25(21)33)13-14-23(20)18-31-30(37)34-19-24(29(38-4)39-5)17-26(34)28(36)32(2)3/h6-7,10,12-14,16,24,26,29H,8-9,11,15,17-19H2,1-5H3,(H,31,37)/t24?,26-/m0/s1
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n/an/an/an/a 20n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246644
PNG
(1-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1-benzazepin-1-...)
Show SMILES CN(C)C(=O)[C@@H]1CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCC(O)c2ccccc12
Show InChI InChI=1S/C27H34N4O4/c1-18-16-19(25(33)30-14-7-11-24(32)21-8-4-5-9-22(21)30)12-13-20(18)17-28-27(35)31-15-6-10-23(31)26(34)29(2)3/h4-5,8-9,12-13,16,23-24,32H,6-7,10-11,14-15,17H2,1-3H3,(H,28,35)/t23-,24?/m0/s1
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n/an/an/an/a 230n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246645
PNG
(1-(2-Methyl-4-(5-methyl-2,3,4,5-tetrahydro-1-benza...)
Show SMILES CC1CCCN(C(=O)c2ccc(CNC(=O)N3CCC[C@H]3C(=O)N(C)C)c(C)c2)c2ccccc12
Show InChI InChI=1S/C28H36N4O3/c1-19-9-7-15-31(24-11-6-5-10-23(19)24)26(33)21-13-14-22(20(2)17-21)18-29-28(35)32-16-8-12-25(32)27(34)30(3)4/h5-6,10-11,13-14,17,19,25H,7-9,12,15-16,18H2,1-4H3,(H,29,35)/t19?,25-/m0/s1
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n/an/an/an/a 220n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246719
PNG
(1-(4-(5,5-Difluoro-2,3,4,5-tetrahydro-1-benzazepin...)
Show SMILES CN(C)C(=O)[C@@H]1CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCC(F)(F)c2ccccc12
Show InChI InChI=1S/C27H32F2N4O3/c1-18-16-19(24(34)32-15-7-13-27(28,29)21-8-4-5-9-22(21)32)11-12-20(18)17-30-26(36)33-14-6-10-23(33)25(35)31(2)3/h4-5,8-9,11-12,16,23H,6-7,10,13-15,17H2,1-3H3,(H,30,36)/t23-/m0/s1
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n/an/an/an/a 1.70E+3n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 Receptor


(Rattus norvegicus (Rat))
BDBM50246609
PNG
((4R)-4-Ethoxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1-...)
Show SMILES CCO[C@@H]1C[C@H](N(C1)C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12)C(=O)N(C)C
Show InChI InChI=1S/C29H38N4O4/c1-5-37-24-17-26(28(35)31(3)4)33(19-24)29(36)30-18-23-14-13-22(16-20(23)2)27(34)32-15-9-8-11-21-10-6-7-12-25(21)32/h6-7,10,12-14,16,24,26H,5,8-9,11,15,17-19H2,1-4H3,(H,30,36)/t24-,26+/m1/s1
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Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at rat vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase reporter...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 Receptor


(Rattus norvegicus (Rat))
BDBM50246608
PNG
((4R)-4-Methoxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1...)
Show SMILES CO[C@@H]1C[C@H](N(C1)C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12)C(=O)N(C)C
Show InChI InChI=1S/C28H36N4O4/c1-19-15-21(26(33)31-14-8-7-10-20-9-5-6-11-24(20)31)12-13-22(19)17-29-28(35)32-18-23(36-4)16-25(32)27(34)30(2)3/h5-6,9,11-13,15,23,25H,7-8,10,14,16-18H2,1-4H3,(H,29,35)/t23-,25+/m1/s1
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n/an/an/an/a 65n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at rat vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase reporter...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 Receptor


(Rattus norvegicus (Rat))
BDBM50246596
PNG
((4R)-4-Hydroxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1...)
Show SMILES CN(C)C(=O)[C@@H]1C[C@@H](O)CN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C27H34N4O4/c1-18-14-20(25(33)30-13-7-6-9-19-8-4-5-10-23(19)30)11-12-21(18)16-28-27(35)31-17-22(32)15-24(31)26(34)29(2)3/h4-5,8,10-12,14,22,24,32H,6-7,9,13,15-17H2,1-3H3,(H,28,35)/t22-,24+/m1/s1
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n/an/an/an/a 41n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at rat vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase reporter...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 Receptor


(Rattus norvegicus (Rat))
BDBM50246575
PNG
(1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-y...)
Show SMILES CN(C)C(=O)[C@@H]1CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C27H34N4O3/c1-19-17-21(25(32)30-15-7-6-10-20-9-4-5-11-23(20)30)13-14-22(19)18-28-27(34)31-16-8-12-24(31)26(33)29(2)3/h4-5,9,11,13-14,17,24H,6-8,10,12,15-16,18H2,1-3H3,(H,28,34)/t24-/m0/s1
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n/an/an/an/a 150n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at rat vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase reporter...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 Receptor


(Rattus norvegicus (Rat))
BDBM50240946
PNG
(1-(4-[N-(2-dimethylamino-2-oxoethylcarbamoyl)amino...)
Show SMILES CN(C)C(=O)CNC(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C24H30N4O3/c1-17-14-19(11-12-20(17)15-25-24(31)26-16-22(29)27(2)3)23(30)28-13-7-6-9-18-8-4-5-10-21(18)28/h4-5,8,10-12,14H,6-7,9,13,15-16H2,1-3H3,(H2,25,26,31)
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Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at rat vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase reporter...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50247100
PNG
(1-(4-[N-(2-Benzylamino-2-oxoethylcarbamoyl]aminome...)
Show SMILES Cc1cc(ccc1CNC(=O)NCC(=O)NCc1ccccc1)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C29H32N4O3/c1-21-17-24(28(35)33-16-8-7-12-23-11-5-6-13-26(23)33)14-15-25(21)19-31-29(36)32-20-27(34)30-18-22-9-3-2-4-10-22/h2-6,9-11,13-15,17H,7-8,12,16,18-20H2,1H3,(H,30,34)(H2,31,32,36)
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n/an/an/an/a 270n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50240946
PNG
(1-(4-[N-(2-dimethylamino-2-oxoethylcarbamoyl)amino...)
Show SMILES CN(C)C(=O)CNC(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C24H30N4O3/c1-17-14-19(11-12-20(17)15-25-24(31)26-16-22(29)27(2)3)23(30)28-13-7-6-9-18-8-4-5-10-21(18)28/h4-5,8,10-12,14H,6-7,9,13,15-16H2,1-3H3,(H2,25,26,31)
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n/an/an/an/a 58n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50247101
PNG
(1-(4-[N-(2-Pyrrolidin-1-yl-2-oxoethylcarbamoyl]ami...)
Show SMILES Cc1cc(ccc1CNC(=O)NCC(=O)N1CCCC1)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C26H32N4O3/c1-19-16-21(25(32)30-15-5-4-9-20-8-2-3-10-23(20)30)11-12-22(19)17-27-26(33)28-18-24(31)29-13-6-7-14-29/h2-3,8,10-12,16H,4-7,9,13-15,17-18H2,1H3,(H2,27,28,33)
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Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246575
PNG
(1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-y...)
Show SMILES CN(C)C(=O)[C@@H]1CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C27H34N4O3/c1-19-17-21(25(32)30-15-7-6-10-20-9-4-5-11-23(20)30)13-14-22(19)18-28-27(34)31-16-8-12-24(31)26(33)29(2)3/h4-5,9,11,13-14,17,24H,6-8,10,12,15-16,18H2,1-3H3,(H,28,34)/t24-/m0/s1
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n/an/an/an/a 24n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246576
PNG
(1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-y...)
Show SMILES CCN(CC)C(=O)[C@@H]1CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C29H38N4O3/c1-4-31(5-2)28(35)26-14-10-18-33(26)29(36)30-20-24-16-15-23(19-21(24)3)27(34)32-17-9-8-12-22-11-6-7-13-25(22)32/h6-7,11,13,15-16,19,26H,4-5,8-10,12,14,17-18,20H2,1-3H3,(H,30,36)/t26-/m0/s1
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n/an/an/an/a 350n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246578
PNG
(1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-y...)
Show SMILES CN(C)C(=S)[C@@H]1CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C27H34N4O2S/c1-19-17-21(25(32)30-15-7-6-10-20-9-4-5-11-23(20)30)13-14-22(19)18-28-27(33)31-16-8-12-24(31)26(34)29(2)3/h4-5,9,11,13-14,17,24H,6-8,10,12,15-16,18H2,1-3H3,(H,28,33)/t24-/m0/s1
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n/an/an/an/a 3.20n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246596
PNG
((4R)-4-Hydroxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1...)
Show SMILES CN(C)C(=O)[C@@H]1C[C@@H](O)CN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C27H34N4O4/c1-18-14-20(25(33)30-13-7-6-9-19-8-4-5-10-23(19)30)11-12-21(18)16-28-27(35)31-17-22(32)15-24(31)26(34)29(2)3/h4-5,8,10-12,14,22,24,32H,6-7,9,13,15-17H2,1-3H3,(H,28,35)/t22-,24+/m1/s1
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n/an/an/an/a 2.30n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246608
PNG
((4R)-4-Methoxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1...)
Show SMILES CO[C@@H]1C[C@H](N(C1)C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12)C(=O)N(C)C
Show InChI InChI=1S/C28H36N4O4/c1-19-15-21(26(33)31-14-8-7-10-20-9-5-6-11-24(20)31)12-13-22(19)17-29-28(35)32-18-23(36-4)16-25(32)27(34)30(2)3/h5-6,9,11-13,15,23,25H,7-8,10,14,16-18H2,1-4H3,(H,29,35)/t23-,25+/m1/s1
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n/an/an/an/a 4.70n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246609
PNG
((4R)-4-Ethoxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1-...)
Show SMILES CCO[C@@H]1C[C@H](N(C1)C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12)C(=O)N(C)C
Show InChI InChI=1S/C29H38N4O4/c1-5-37-24-17-26(28(35)31(3)4)33(19-24)29(36)30-18-23-14-13-22(16-20(23)2)27(34)32-15-9-8-11-21-10-6-7-12-25(21)32/h6-7,10,12-14,16,24,26H,5,8-9,11,15,17-19H2,1-4H3,(H,30,36)/t24-,26+/m1/s1
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n/an/an/an/a 4.30n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair