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2 similar compounds to monomer 50247613

Wt: 395.4
BDBM50247612
Wt: 385.8
BDBM50247776

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247612,50247776   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247776
PNG
((3S,4R)-4-(5-Chloro-1H-benzoimidazol-2-ylsulfanyl)...)
Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Sc2nc3ccc(Cl)cc3[nH]2)[C@@H]1O)C#N
Show InChI InChI=1S/C19H16ClN3O2S/c1-19(2)17(24)16(12-7-10(9-21)3-6-15(12)25-19)26-18-22-13-5-4-11(20)8-14(13)23-18/h3-8,16-17,24H,1-2H3,(H,22,23)/t16-,17+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.47E+4n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247612
PNG
((3S,4R)-4-(5-Ethoxy-benzothiazol-2-ylamino)-3-hydr...)
Show SMILES CCOc1ccc2nc(S[C@H]3[C@H](O)C(C)(C)Oc4ccc(cc34)C#N)[nH]c2c1
Show InChI InChI=1S/C21H21N3O3S/c1-4-26-13-6-7-15-16(10-13)24-20(23-15)28-18-14-9-12(11-22)5-8-17(14)27-21(2,3)19(18)25/h5-10,18-19,25H,4H2,1-3H3,(H,23,24)/t18-,19+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 2.60E+3n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Citation and Details
More data for this
Ligand-Target Pair