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2 similar compounds to monomer 50247762

Wt: 355.8
BDBM50247763
Wt: 355.8
BDBM50247765

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247763,50247765   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247765
PNG
((3S,4R) 4-[5-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-...)
Show SMILES CC1(C)Oc2ccncc2[C@H]([C@@H]1O)n1cncc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H18ClN3O2/c1-19(2)18(24)17(14-9-21-8-7-16(14)25-19)23-11-22-10-15(23)12-3-5-13(20)6-4-12/h3-11,17-18,24H,1-2H3/t17-,18+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.38E+4n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247763
PNG
((3S,4R)-4-[2-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-...)
Show SMILES CC1(C)Oc2ccncc2[C@H]([C@@H]1O)n1ccnc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H18ClN3O2/c1-19(2)17(24)16(14-11-21-8-7-15(14)25-19)23-10-9-22-18(23)12-3-5-13(20)6-4-12/h3-11,16-17,24H,1-2H3/t16-,17+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 4.33E+3n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Citation and Details
More data for this
Ligand-Target Pair