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1 similar compounds to monomer 50249446

Compile data set for download or QSAR
Wt: 317.3
BDBM50249448

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249448   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin K


(Homo sapiens (Human))
BDBM50249448
PNG
(4-(4-acetylpiperazin-1-yl)-5-amino-6-(isobutylamin...)
Show SMILES CC(C)CNc1nc(nc(N2CCN(CC2)C(C)=O)c1N)C#N
Show InChI InChI=1S/C15H23N7O/c1-10(2)9-18-14-13(17)15(20-12(8-16)19-14)22-6-4-21(5-7-22)11(3)23/h10H,4-7,9,17H2,1-3H3,(H,18,19,20)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 9n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of cathepsin K (unknown origin)


Bioorg Med Chem Lett 19: 1658-61 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.110
BindingDB Entry DOI: 10.7270/Q2571BWR
More data for this
Ligand-Target Pair