BindingDB logo
myBDB logout

3 similar compounds to monomer 50208827

Compile data set for download or QSAR
Wt: 338.3
BDBM50264095
Purchase
Wt: 232.2
BDBM50430487
Wt: 218.2
BDBM50430488

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264095,50430487,50430488   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl Cholesterol Acyltransferase 1 (ACAT-1)


(Homo sapiens (Human))
BDBM50430487
PNG
(CHEMBL2335532)
Show SMILES CCCSC1=CC(=O)c2ccccc2C1=O
Show InChI InChI=1S/C13H12O2S/c1-2-7-16-12-8-11(14)9-5-3-4-6-10(9)13(12)15/h3-6,8H,2,7H2,1H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.08E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate additi...


Eur J Med Chem 62: 515-25 (2013)


Article DOI: 10.1016/j.ejmech.2013.01.020
BindingDB Entry DOI: 10.7270/Q29G5P5N
More data for this
Ligand-Target Pair
Dual specificity phosphatase Cdc25B


(Homo sapiens (Human))
BDBM50264095
PNG
((3-Carboxymethylsulfanyl-1,4-dioxo-1,4-dihydro-nap...)
Show SMILES OC(=O)CSC1=C(SCC(O)=O)C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C14H10O6S2/c15-9(16)5-21-13-11(19)7-3-1-2-4-8(7)12(20)14(13)22-6-10(17)18/h1-4H,5-6H2,(H,15,16)(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.75E+3n/an/an/an/an/an/a



Universit£ Paris Descartes

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDC25B


Bioorg Med Chem 16: 9040-9 (2008)


Article DOI: 10.1016/j.bmc.2008.08.009
BindingDB Entry DOI: 10.7270/Q2833SZB
More data for this
Ligand-Target Pair
Acyl Cholesterol Acyltransferase 1 (ACAT-1)


(Homo sapiens (Human))
BDBM50430488
PNG
(CHEMBL531383 | GNF-Pf-2144)
Show SMILES CCSC1=CC(=O)c2ccccc2C1=O
Show InChI InChI=1S/C12H10O2S/c1-2-15-11-7-10(13)8-5-3-4-6-9(8)12(11)14/h3-7H,2H2,1H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.51E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate additi...


Eur J Med Chem 62: 515-25 (2013)


Article DOI: 10.1016/j.ejmech.2013.01.020
BindingDB Entry DOI: 10.7270/Q29G5P5N
More data for this
Ligand-Target Pair