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12 similar compounds to monomer 50265643

Compile data set for download or QSAR
Wt: 379.4
BDBM50265616
Wt: 365.4
BDBM50265617
Wt: 351.3
BDBM50265618
Wt: 391.4
BDBM50265619
Wt: 385.4
BDBM50265620
Wt: 405.4
BDBM50265642
Wt: 345.4
BDBM50265680
Wt: 345.4
BDBM50265683
Wt: 379.4
BDBM50273100
Wt: 307.3
BDBM50272910
Purchase
Wt: 321.3
BDBM50273134
Wt: 335.3
BDBM50273135

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50265616,50265617,50265618,50265619,50265620,50265642,50265680,50265683,50273100,50272910,50273134,50273135   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50273134
PNG
(CHEMBL456803 | N-[(3Z)-1-(1-Butyl)-2-oxo-1,2-dihyd...)
Show SMILES CCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C19H19N3O2/c1-2-3-13-22-16-12-8-7-11-15(16)17(19(22)24)20-21-18(23)14-9-5-4-6-10-14/h4-12H,2-3,13H2,1H3,(H,21,23)/b20-17-
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PubMed
19.3n/an/an/an/an/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHOK1 cells by liquid scintillation counting


J Med Chem 51: 4932-47 (2008)


Article DOI: 10.1021/jm8002203
BindingDB Entry DOI: 10.7270/Q2X067ZQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50265616
PNG
(CHEMBL497183 | N'-[(3Z)-1-Hexyl-6-methoxy-2-oxo-1,...)
Show SMILES CCCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12
Show InChI InChI=1S/C22H25N3O3/c1-3-4-5-9-14-25-19-15-17(28-2)12-13-18(19)20(22(25)27)23-24-21(26)16-10-7-6-8-11-16/h6-8,10-13,15H,3-5,9,14H2,1-2H3,(H,24,26)/b23-20-
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89.9n/an/an/an/an/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Binding affinity to CB2 receptor


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50265616
PNG
(CHEMBL497183 | N'-[(3Z)-1-Hexyl-6-methoxy-2-oxo-1,...)
Show SMILES CCCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12
Show InChI InChI=1S/C22H25N3O3/c1-3-4-5-9-14-25-19-15-17(28-2)12-13-18(19)20(22(25)27)23-24-21(26)16-10-7-6-8-11-16/h6-8,10-13,15H,3-5,9,14H2,1-2H3,(H,24,26)/b23-20-
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89.9n/an/an/an/an/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Displacement of [3H] 2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol from human CB2 receptor expressed CHO-K1 cel...


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50272910
PNG
(CHEMBL455951 | N-[(3Z)-1-(1-Propyl)-2-oxo-1,2-dihy...)
Show SMILES CCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C18H17N3O2/c1-2-12-21-15-11-7-6-10-14(15)16(18(21)23)19-20-17(22)13-8-4-3-5-9-13/h3-11H,2,12H2,1H3,(H,20,22)/b19-16-
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n/an/an/an/a 201n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTPgammaS assay


J Med Chem 51: 4932-47 (2008)


Article DOI: 10.1021/jm8002203
BindingDB Entry DOI: 10.7270/Q2X067ZQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50273100
PNG
(CHEMBL458492 | N-[(3Z)-1-Hexyl-2-oxo-1,2-dihydro-3...)
Show SMILES CCCCCCN1C(=O)C(=NNC(=O)c2ccc(OC)cc2)c2ccccc12
Show InChI InChI=1S/C22H25N3O3/c1-3-4-5-8-15-25-19-10-7-6-9-18(19)20(22(25)27)23-24-21(26)16-11-13-17(28-2)14-12-16/h6-7,9-14H,3-5,8,15H2,1-2H3,(H,24,26)/b23-20-
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n/an/an/an/a 143n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTPgammaS assay


J Med Chem 51: 4932-47 (2008)


Article DOI: 10.1021/jm8002203
BindingDB Entry DOI: 10.7270/Q2X067ZQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50265683
PNG
(CHEMBL496370 | N'-[(3Z)-6-Methoxy-1-pentyl-2-oxo-1...)
Show SMILES CCCCCN1C(=O)C(=NNC(=O)C(C)(C)C)c2ccc(OC)cc12
Show InChI InChI=1S/C19H27N3O3/c1-6-7-8-11-22-15-12-13(25-5)9-10-14(15)16(17(22)23)20-21-18(24)19(2,3)4/h9-10,12H,6-8,11H2,1-5H3,(H,21,24)/b20-16-
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50265680
PNG
(CHEMBL495966 | N'-[(3Z)-6-Methoxy-1-pentyl-2-oxo-1...)
Show SMILES CCCCCN1C(=O)C(=NNC(=O)CC(C)C)c2ccc(OC)cc12
Show InChI InChI=1S/C19H27N3O3/c1-5-6-7-10-22-16-12-14(25-4)8-9-15(16)18(19(22)24)21-20-17(23)11-13(2)3/h8-9,12-13H,5-7,10-11H2,1-4H3,(H,20,23)/b21-18-
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50265619
PNG
(CHEMBL495738 | N'-[(3Z)-1-(Cyclohexylmethyl)-6-met...)
Show SMILES COc1ccc2C(=NNC(=O)c3ccccc3)C(=O)N(CC3CCCCC3)c2c1
Show InChI InChI=1S/C23H25N3O3/c1-29-18-12-13-19-20(14-18)26(15-16-8-4-2-5-9-16)23(28)21(19)24-25-22(27)17-10-6-3-7-11-17/h3,6-7,10-14,16H,2,4-5,8-9,15H2,1H3,(H,25,27)/b24-21-
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n/an/an/an/a 61.2n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50265617
PNG
(CHEMBL523084 | N'-[(3Z)-6-Methoxy-1-pentyl-2-oxo-1...)
Show SMILES CCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12
Show InChI InChI=1S/C21H23N3O3/c1-3-4-8-13-24-18-14-16(27-2)11-12-17(18)19(21(24)26)22-23-20(25)15-9-6-5-7-10-15/h5-7,9-12,14H,3-4,8,13H2,1-2H3,(H,23,25)/b22-19-
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n/an/an/an/a 263n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50265616
PNG
(CHEMBL497183 | N'-[(3Z)-1-Hexyl-6-methoxy-2-oxo-1,...)
Show SMILES CCCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12
Show InChI InChI=1S/C22H25N3O3/c1-3-4-5-9-14-25-19-15-17(28-2)12-13-18(19)20(22(25)27)23-24-21(26)16-10-7-6-8-11-16/h6-8,10-13,15H,3-5,9,14H2,1-2H3,(H,24,26)/b23-20-
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50265683
PNG
(CHEMBL496370 | N'-[(3Z)-6-Methoxy-1-pentyl-2-oxo-1...)
Show SMILES CCCCCN1C(=O)C(=NNC(=O)C(C)(C)C)c2ccc(OC)cc12
Show InChI InChI=1S/C19H27N3O3/c1-6-7-8-11-22-15-12-13(25-5)9-10-14(15)16(17(22)23)20-21-18(24)19(2,3)4/h9-10,12H,6-8,11H2,1-5H3,(H,21,24)/b20-16-
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n/an/an/an/a 10n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50265680
PNG
(CHEMBL495966 | N'-[(3Z)-6-Methoxy-1-pentyl-2-oxo-1...)
Show SMILES CCCCCN1C(=O)C(=NNC(=O)CC(C)C)c2ccc(OC)cc12
Show InChI InChI=1S/C19H27N3O3/c1-5-6-7-10-22-16-12-14(25-4)8-9-15(16)18(19(22)24)21-20-17(23)11-13(2)3/h8-9,12-13H,5-7,10-11H2,1-4H3,(H,20,23)/b21-18-
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n/an/an/an/a 11.7n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50265642
PNG
(CHEMBL498215 | N'-[(3Z)-1-(2-Cyclohexylethyl)-6-me...)
Show SMILES COc1ccc2C(=NNC(=O)c3ccccc3)C(=O)N(CCC3CCCCC3)c2c1
Show InChI InChI=1S/C24H27N3O3/c1-30-19-12-13-20-21(16-19)27(15-14-17-8-4-2-5-9-17)24(29)22(20)25-26-23(28)18-10-6-3-7-11-18/h3,6-7,10-13,16-17H,2,4-5,8-9,14-15H2,1H3,(H,26,28)/b25-22-
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n/an/an/an/a 540n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50265620
PNG
(CHEMBL522382 | N'-[(3Z)-1-Benzyl-6-methoxy-2-oxo-1...)
Show SMILES COc1ccc2C(=NNC(=O)c3ccccc3)C(=O)N(Cc3ccccc3)c2c1
Show InChI InChI=1S/C23H19N3O3/c1-29-18-12-13-19-20(14-18)26(15-16-8-4-2-5-9-16)23(28)21(19)24-25-22(27)17-10-6-3-7-11-17/h2-14H,15H2,1H3,(H,25,27)/b24-21-
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n/an/an/an/a 102n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50265619
PNG
(CHEMBL495738 | N'-[(3Z)-1-(Cyclohexylmethyl)-6-met...)
Show SMILES COc1ccc2C(=NNC(=O)c3ccccc3)C(=O)N(CC3CCCCC3)c2c1
Show InChI InChI=1S/C23H25N3O3/c1-29-18-12-13-19-20(14-18)26(15-16-8-4-2-5-9-16)23(28)21(19)24-25-22(27)17-10-6-3-7-11-17/h3,6-7,10-14,16H,2,4-5,8-9,15H2,1H3,(H,25,27)/b24-21-
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n/an/an/an/a 18n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50265618
PNG
(CHEMBL495533 | N'-[(3Z)-1-Butyl-6-methoxy-2-oxo-1,...)
Show SMILES CCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12
Show InChI InChI=1S/C20H21N3O3/c1-3-4-12-23-17-13-15(26-2)10-11-16(17)18(20(23)25)21-22-19(24)14-8-6-5-7-9-14/h5-11,13H,3-4,12H2,1-2H3,(H,22,24)/b21-18-
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n/an/an/an/a 85n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50265617
PNG
(CHEMBL523084 | N'-[(3Z)-6-Methoxy-1-pentyl-2-oxo-1...)
Show SMILES CCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12
Show InChI InChI=1S/C21H23N3O3/c1-3-4-8-13-24-18-14-16(27-2)11-12-17(18)19(21(24)26)22-23-20(25)15-9-6-5-7-10-15/h5-7,9-12,14H,3-4,8,13H2,1-2H3,(H,23,25)/b22-19-
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n/an/an/an/a 5.80n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50265616
PNG
(CHEMBL497183 | N'-[(3Z)-1-Hexyl-6-methoxy-2-oxo-1,...)
Show SMILES CCCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12
Show InChI InChI=1S/C22H25N3O3/c1-3-4-5-9-14-25-19-15-17(28-2)12-13-18(19)20(22(25)27)23-24-21(26)16-10-7-6-8-11-16/h6-8,10-13,15H,3-5,9,14H2,1-2H3,(H,24,26)/b23-20-
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n/an/an/an/a 88.2n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50265642
PNG
(CHEMBL498215 | N'-[(3Z)-1-(2-Cyclohexylethyl)-6-me...)
Show SMILES COc1ccc2C(=NNC(=O)c3ccccc3)C(=O)N(CCC3CCCCC3)c2c1
Show InChI InChI=1S/C24H27N3O3/c1-30-19-12-13-20-21(16-19)27(15-14-17-8-4-2-5-9-17)24(29)22(20)25-26-23(28)18-10-6-3-7-11-18/h3,6-7,10-13,16-17H,2,4-5,8-9,14-15H2,1H3,(H,26,28)/b25-22-
PDB

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PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50265620
PNG
(CHEMBL522382 | N'-[(3Z)-1-Benzyl-6-methoxy-2-oxo-1...)
Show SMILES COc1ccc2C(=NNC(=O)c3ccccc3)C(=O)N(Cc3ccccc3)c2c1
Show InChI InChI=1S/C23H19N3O3/c1-29-18-12-13-19-20(14-18)26(15-16-8-4-2-5-9-16)23(28)21(19)24-25-22(27)17-10-6-3-7-11-17/h2-14H,15H2,1H3,(H,25,27)/b24-21-
PDB

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Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50265618
PNG
(CHEMBL495533 | N'-[(3Z)-1-Butyl-6-methoxy-2-oxo-1,...)
Show SMILES CCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12
Show InChI InChI=1S/C20H21N3O3/c1-3-4-12-23-17-13-15(26-2)10-11-16(17)18(20(23)25)21-22-19(24)14-8-6-5-7-9-14/h5-11,13H,3-4,12H2,1-2H3,(H,22,24)/b21-18-
PDB

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Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50273134
PNG
(CHEMBL456803 | N-[(3Z)-1-(1-Butyl)-2-oxo-1,2-dihyd...)
Show SMILES CCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C19H19N3O2/c1-2-3-13-22-16-12-8-7-11-15(16)17(19(22)24)20-21-18(23)14-9-5-4-6-10-14/h4-12H,2-3,13H2,1H3,(H,21,23)/b20-17-
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PubMed
n/an/an/an/a 40.1n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTPgammaS assay


J Med Chem 51: 4932-47 (2008)


Article DOI: 10.1021/jm8002203
BindingDB Entry DOI: 10.7270/Q2X067ZQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50273100
PNG
(CHEMBL458492 | N-[(3Z)-1-Hexyl-2-oxo-1,2-dihydro-3...)
Show SMILES CCCCCCN1C(=O)C(=NNC(=O)c2ccc(OC)cc2)c2ccccc12
Show InChI InChI=1S/C22H25N3O3/c1-3-4-5-8-15-25-19-10-7-6-9-18(19)20(22(25)27)23-24-21(26)16-11-13-17(28-2)14-12-16/h6-7,9-14H,3-5,8,15H2,1-2H3,(H,24,26)/b23-20-
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PubMed
n/an/an/an/a 852n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells by [35S]GTPgammaS assay


J Med Chem 51: 4932-47 (2008)


Article DOI: 10.1021/jm8002203
BindingDB Entry DOI: 10.7270/Q2X067ZQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50273135
PNG
(CHEMBL504754 | N-[(3Z)-1-(1-Pentyl)-2-oxo-1,2-dihy...)
Show SMILES CCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C20H21N3O2/c1-2-3-9-14-23-17-13-8-7-12-16(17)18(20(23)25)21-22-19(24)15-10-5-4-6-11-15/h4-8,10-13H,2-3,9,14H2,1H3,(H,22,24)/b21-18-
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Article
PubMed
n/an/an/an/a 240n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTPgammaS assay


J Med Chem 51: 4932-47 (2008)


Article DOI: 10.1021/jm8002203
BindingDB Entry DOI: 10.7270/Q2X067ZQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50273135
PNG
(CHEMBL504754 | N-[(3Z)-1-(1-Pentyl)-2-oxo-1,2-dihy...)
Show SMILES CCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C20H21N3O2/c1-2-3-9-14-23-17-13-8-7-12-16(17)18(20(23)25)21-22-19(24)15-10-5-4-6-11-15/h4-8,10-13H,2-3,9,14H2,1H3,(H,22,24)/b21-18-
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Article
PubMed
n/an/an/an/a 314n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells by [35S]GTPgammaS assay


J Med Chem 51: 4932-47 (2008)


Article DOI: 10.1021/jm8002203
BindingDB Entry DOI: 10.7270/Q2X067ZQ
More data for this
Ligand-Target Pair