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16 similar compounds to monomer 50266051

Compile data set for download or QSAR
Wt: 394.5
BDBM50266085
Wt: 470.6
BDBM50266086
Wt: 284.3
BDBM50265981
Wt: 326.4
BDBM50265982
Wt: 328.3
BDBM50265983
Wt: 342.4
BDBM50265984
Wt: 355.4
BDBM50265985
Wt: 395.4
BDBM50265986
Wt: 388.4
BDBM50266052
Wt: 298.3
BDBM50266053
Wt: 374.4
BDBM50266054
Wt: 364.4
BDBM50266055
Wt: 396.4
BDBM50266019
Wt: 350.3
BDBM50266020
Wt: 366.4
BDBM50266021
Displayed 1 to 15 (of 16 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50266085,50266086,50265981,50265982,50265983,50265984,50265985,50265986,50266052,50266053,50266054,50266055,50266019,50266020,50266021   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50266020
PNG
((4-(furan-2-yl)-2-(furan-2-ylmethylamino)thiazol-5...)
Show SMILES O=C(c1sc(NCc2ccco2)nc1-c1ccco1)c1ccccc1
Show InChI InChI=1S/C19H14N2O3S/c22-17(13-6-2-1-3-7-13)18-16(15-9-5-11-24-15)21-19(25-18)20-12-14-8-4-10-23-14/h1-11H,12H2,(H,20,21)
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43n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50266021
PNG
((4-(furan-2-yl)-2-(thiophen-2-ylmethylamino)thiazo...)
Show SMILES O=C(c1sc(NCc2cccs2)nc1-c1ccco1)c1ccccc1
Show InChI InChI=1S/C19H14N2O2S2/c22-17(13-6-2-1-3-7-13)18-16(15-9-4-10-23-15)21-19(25-18)20-12-14-8-5-11-24-14/h1-11H,12H2,(H,20,21)
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54n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50266019
PNG
((2-(3,4-difluorobenzylamino)-4-(furan-2-yl)thiazol...)
Show SMILES Fc1ccc(CNc2nc(-c3ccco3)c(s2)C(=O)c2ccccc2)cc1F
Show InChI InChI=1S/C21H14F2N2O2S/c22-15-9-8-13(11-16(15)23)12-24-21-25-18(17-7-4-10-27-17)20(28-21)19(26)14-5-2-1-3-6-14/h1-11H,12H2,(H,24,25)
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64n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50265981
PNG
((4-(furan-2-yl)-2-(methylamino)thiazol-5-yl)(pheny...)
Show SMILES CNc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C15H12N2O2S/c1-16-15-17-12(11-8-5-9-19-11)14(20-15)13(18)10-6-3-2-4-7-10/h2-9H,1H3,(H,16,17)
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67n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50265982
PNG
((4-(furan-2-yl)-2-(isobutylamino)thiazol-5-yl)(phe...)
Show SMILES CC(C)CNc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C18H18N2O2S/c1-12(2)11-19-18-20-15(14-9-6-10-22-14)17(23-18)16(21)13-7-4-3-5-8-13/h3-10,12H,11H2,1-2H3,(H,19,20)
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89n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50266052
PNG
((4-(furan-2-yl)-2-(3-phenylpropylamino)thiazol-5-y...)
Show SMILES O=C(c1sc(NCCCc2ccccc2)nc1-c1ccco1)c1ccccc1
Show InChI InChI=1S/C23H20N2O2S/c26-21(18-12-5-2-6-13-18)22-20(19-14-8-16-27-19)25-23(28-22)24-15-7-11-17-9-3-1-4-10-17/h1-6,8-10,12-14,16H,7,11,15H2,(H,24,25)
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105n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50265984
PNG
((4-(furan-2-yl)-2-(2-methoxypropylamino)thiazol-5-...)
Show SMILES COC(C)CNc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C18H18N2O3S/c1-12(22-2)11-19-18-20-15(14-9-6-10-23-14)17(24-18)16(21)13-7-4-3-5-8-13/h3-10,12H,11H2,1-2H3,(H,19,20)
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154n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50266055
PNG
((4-(furan-2-yl)-2-((furan-2-ylmethyl)(methyl)amino...)
Show SMILES CN(Cc1ccco1)c1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C20H16N2O3S/c1-22(13-15-9-5-11-24-15)20-21-17(16-10-6-12-25-16)19(26-20)18(23)14-7-3-2-4-8-14/h2-12H,13H2,1H3
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160n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50265983
PNG
((4-(furan-2-yl)-2-(2-methoxyethylamino)thiazol-5-y...)
Show SMILES COCCNc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C17H16N2O3S/c1-21-11-9-18-17-19-14(13-8-5-10-22-13)16(23-17)15(20)12-6-3-2-4-7-12/h2-8,10H,9,11H2,1H3,(H,18,19)
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195n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50265985
PNG
(CHEMBL460172 | N-(2-(5-benzoyl-4-(furan-2-yl)thiaz...)
Show SMILES CC(=O)NCCNc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C18H17N3O3S/c1-12(22)19-9-10-20-18-21-15(14-8-5-11-24-14)17(25-18)16(23)13-6-3-2-4-7-13/h2-8,11H,9-10H2,1H3,(H,19,22)(H,20,21)
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281n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50265986
PNG
(1-(4-(5-benzoyl-4-(furan-2-yl)thiazol-2-ylamino)pi...)
Show SMILES CC(=O)N1CCC(CC1)Nc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C21H21N3O3S/c1-14(25)24-11-9-16(10-12-24)22-21-23-18(17-8-5-13-27-17)20(28-21)19(26)15-6-3-2-4-7-15/h2-8,13,16H,9-12H2,1H3,(H,22,23)
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455n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50265986
PNG
(1-(4-(5-benzoyl-4-(furan-2-yl)thiazol-2-ylamino)pi...)
Show SMILES CC(=O)N1CCC(CC1)Nc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C21H21N3O3S/c1-14(25)24-11-9-16(10-12-24)22-21-23-18(17-8-5-13-27-17)20(28-21)19(26)15-6-3-2-4-7-15/h2-8,13,16H,9-12H2,1H3,(H,22,23)
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1.24E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50265982
PNG
((4-(furan-2-yl)-2-(isobutylamino)thiazol-5-yl)(phe...)
Show SMILES CC(C)CNc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C18H18N2O2S/c1-12(2)11-19-18-20-15(14-9-6-10-22-14)17(23-18)16(21)13-7-4-3-5-8-13/h3-10,12H,11H2,1-2H3,(H,19,20)
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1.28E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50266020
PNG
((4-(furan-2-yl)-2-(furan-2-ylmethylamino)thiazol-5...)
Show SMILES O=C(c1sc(NCc2ccco2)nc1-c1ccco1)c1ccccc1
Show InChI InChI=1S/C19H14N2O3S/c22-17(13-6-2-1-3-7-13)18-16(15-9-5-11-24-15)21-19(25-18)20-12-14-8-4-10-23-14/h1-11H,12H2,(H,20,21)
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1.46E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50265985
PNG
(CHEMBL460172 | N-(2-(5-benzoyl-4-(furan-2-yl)thiaz...)
Show SMILES CC(=O)NCCNc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C18H17N3O3S/c1-12(22)19-9-10-20-18-21-15(14-8-5-11-24-14)17(25-18)16(23)13-6-3-2-4-7-13/h2-8,11H,9-10H2,1H3,(H,19,22)(H,20,21)
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2.42E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50266054
PNG
((2-(benzyl(methyl)amino)-4-(furan-2-yl)thiazol-5-y...)
Show SMILES CN(Cc1ccccc1)c1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C22H18N2O2S/c1-24(15-16-9-4-2-5-10-16)22-23-19(18-13-8-14-26-18)21(27-22)20(25)17-11-6-3-7-12-17/h2-14H,15H2,1H3
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2.80E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50266021
PNG
((4-(furan-2-yl)-2-(thiophen-2-ylmethylamino)thiazo...)
Show SMILES O=C(c1sc(NCc2cccs2)nc1-c1ccco1)c1ccccc1
Show InChI InChI=1S/C19H14N2O2S2/c22-17(13-6-2-1-3-7-13)18-16(15-9-4-10-23-15)21-19(25-18)20-12-14-8-5-11-24-14/h1-11H,12H2,(H,20,21)
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2.99E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50266055
PNG
((4-(furan-2-yl)-2-((furan-2-ylmethyl)(methyl)amino...)
Show SMILES CN(Cc1ccco1)c1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C20H16N2O3S/c1-22(13-15-9-5-11-24-15)20-21-17(16-10-6-12-25-16)19(26-20)18(23)14-7-3-2-4-8-14/h2-12H,13H2,1H3
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3.42E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50265981
PNG
((4-(furan-2-yl)-2-(methylamino)thiazol-5-yl)(pheny...)
Show SMILES CNc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C15H12N2O2S/c1-16-15-17-12(11-8-5-9-19-11)14(20-15)13(18)10-6-3-2-4-7-10/h2-9H,1H3,(H,16,17)
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3.58E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50265984
PNG
((4-(furan-2-yl)-2-(2-methoxypropylamino)thiazol-5-...)
Show SMILES COC(C)CNc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C18H18N2O3S/c1-12(22-2)11-19-18-20-15(14-9-6-10-23-14)17(24-18)16(21)13-7-4-3-5-8-13/h3-10,12H,11H2,1-2H3,(H,19,20)
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3.97E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50266052
PNG
((4-(furan-2-yl)-2-(3-phenylpropylamino)thiazol-5-y...)
Show SMILES O=C(c1sc(NCCCc2ccccc2)nc1-c1ccco1)c1ccccc1
Show InChI InChI=1S/C23H20N2O2S/c26-21(18-12-5-2-6-13-18)22-20(19-14-8-16-27-19)25-23(28-22)24-15-7-11-17-9-3-1-4-10-17/h1-6,8-10,12-14,16H,7,11,15H2,(H,24,25)
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6.30E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50265983
PNG
((4-(furan-2-yl)-2-(2-methoxyethylamino)thiazol-5-y...)
Show SMILES COCCNc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C17H16N2O3S/c1-21-11-9-18-17-19-14(13-8-5-10-22-13)16(23-17)15(20)12-6-3-2-4-7-12/h2-8,10H,9,11H2,1H3,(H,18,19)
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6.78E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50266053
PNG
((2-(dimethylamino)-4-(furan-2-yl)thiazol-5-yl)(phe...)
Show SMILES CN(C)c1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C16H14N2O2S/c1-18(2)16-17-13(12-9-6-10-20-12)15(21-16)14(19)11-7-4-3-5-8-11/h3-10H,1-2H3
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6.82E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50266086
PNG
((2-(benzyl(2-(thiophen-2-yl)ethyl)amino)-4-(furan-...)
Show SMILES O=C(c1sc(nc1-c1ccco1)N(CCc1cccs1)Cc1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H22N2O2S2/c30-25(21-11-5-2-6-12-21)26-24(23-14-7-17-31-23)28-27(33-26)29(16-15-22-13-8-18-32-22)19-20-9-3-1-4-10-20/h1-14,17-18H,15-16,19H2
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7.14E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50266019
PNG
((2-(3,4-difluorobenzylamino)-4-(furan-2-yl)thiazol...)
Show SMILES Fc1ccc(CNc2nc(-c3ccco3)c(s2)C(=O)c2ccccc2)cc1F
Show InChI InChI=1S/C21H14F2N2O2S/c22-15-9-8-13(11-16(15)23)12-24-21-25-18(17-7-4-10-27-17)20(28-21)19(26)14-5-2-1-3-6-14/h1-11H,12H2,(H,24,25)
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>7.50E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A2


(Homo sapiens (Human))
BDBM50266085
PNG
((4-(furan-2-yl)-2-(methyl(2-(thiophen-2-yl)ethyl)a...)
Show SMILES CN(CCc1cccs1)c1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C21H18N2O2S2/c1-23(12-11-16-9-6-14-26-16)21-22-18(17-10-5-13-25-17)20(27-21)19(24)15-7-3-2-4-8-15/h2-10,13-14H,11-12H2,1H3
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PubMed
8.17E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH-58261 from human recombinant adenosine A2A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50266054
PNG
((2-(benzyl(methyl)amino)-4-(furan-2-yl)thiazol-5-y...)
Show SMILES CN(Cc1ccccc1)c1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C22H18N2O2S/c1-24(15-16-9-4-2-5-10-16)22-23-19(18-13-8-14-26-18)21(27-22)20(25)17-11-6-3-7-12-17/h2-14H,15H2,1H3
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PubMed
9.46E+3n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50266086
PNG
((2-(benzyl(2-(thiophen-2-yl)ethyl)amino)-4-(furan-...)
Show SMILES O=C(c1sc(nc1-c1ccco1)N(CCc1cccs1)Cc1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H22N2O2S2/c30-25(21-11-5-2-6-12-21)26-24(23-14-7-17-31-23)28-27(33-26)29(16-15-22-13-8-18-32-22)19-20-9-3-1-4-10-20/h1-14,17-18H,15-16,19H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50266053
PNG
((2-(dimethylamino)-4-(furan-2-yl)thiazol-5-yl)(phe...)
Show SMILES CN(C)c1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C16H14N2O2S/c1-18(2)16-17-13(12-9-6-10-20-12)15(21-16)14(19)11-7-4-3-5-8-11/h3-10H,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50266085
PNG
((4-(furan-2-yl)-2-(methyl(2-(thiophen-2-yl)ethyl)a...)
Show SMILES CN(CCc1cccs1)c1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Show InChI InChI=1S/C21H18N2O2S2/c1-23(12-11-16-9-6-14-26-16)21-22-18(17-10-5-13-25-17)20(27-21)19(24)15-7-3-2-4-8-15/h2-10,13-14H,11-12H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 19: 378-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.066
BindingDB Entry DOI: 10.7270/Q2348K6P
More data for this
Ligand-Target Pair