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2 similar compounds to monomer 50272365

Compile data set for download or QSAR
Wt: 293.3
BDBM50272366
Wt: 265.3
BDBM50272320

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50272366,50272320   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (human))
BDBM50272366
PNG
(3-(1-Methoxyethyl)-5-(6-methoxynaphthalen-2-yl)pyr...)
Show SMILES COC(C)c1cncc(c1)-c1ccc2cc(OC)ccc2c1
Show InChI InChI=1S/C19H19NO2/c1-13(21-2)17-9-18(12-20-11-17)15-4-5-16-10-19(22-3)7-6-14(16)8-15/h4-13H,1-3H3
PDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.200n/an/an/an/an/an/a



Saarland University

Curated by ChEMBL


Assay Description
Inhibition of human CYP11B2 expressed in hamster V79 MZh cells


J Med Chem 51: 5064-74 (2008)


Article DOI: 10.1021/jm800377h
BindingDB Entry DOI: 10.7270/Q2Z89C75
More data for this
Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial


(Homo sapiens (human))
BDBM50272320
PNG
(CHEMBL448064 | [5-(6-Methoxynaphthalen-2-yl)pyridi...)
Show SMILES COc1ccc2cc(ccc2c1)-c1cncc(CO)c1
Show InChI InChI=1S/C17H15NO2/c1-20-17-5-4-13-7-14(2-3-15(13)8-17)16-6-12(11-19)9-18-10-16/h2-10,19H,11H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 614n/an/an/an/an/an/a



Saarland University

Curated by ChEMBL


Assay Description
Inhibition of human CYP11B1 expressed in hamster V79 MZh cells


J Med Chem 51: 5064-74 (2008)


Article DOI: 10.1021/jm800377h
BindingDB Entry DOI: 10.7270/Q2Z89C75
More data for this
Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial


(Homo sapiens (human))
BDBM50272366
PNG
(3-(1-Methoxyethyl)-5-(6-methoxynaphthalen-2-yl)pyr...)
Show SMILES COC(C)c1cncc(c1)-c1ccc2cc(OC)ccc2c1
Show InChI InChI=1S/C19H19NO2/c1-13(21-2)17-9-18(12-20-11-17)15-4-5-16-10-19(22-3)7-6-14(16)8-15/h4-13H,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Saarland University

Curated by ChEMBL


Assay Description
Inhibition of human CYP11B1 expressed in hamster V79 MZh cells


J Med Chem 51: 5064-74 (2008)


Article DOI: 10.1021/jm800377h
BindingDB Entry DOI: 10.7270/Q2Z89C75
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (human))
BDBM50272320
PNG
(CHEMBL448064 | [5-(6-Methoxynaphthalen-2-yl)pyridi...)
Show SMILES COc1ccc2cc(ccc2c1)-c1cncc(CO)c1
Show InChI InChI=1S/C17H15NO2/c1-20-17-5-4-13-7-14(2-3-15(13)8-17)16-6-12(11-19)9-18-10-16/h2-10,19H,11H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.10n/an/an/an/an/an/a



Saarland University

Curated by ChEMBL


Assay Description
Inhibition of human CYP11B2 expressed in hamster V79 MZh cells


J Med Chem 51: 5064-74 (2008)


Article DOI: 10.1021/jm800377h
BindingDB Entry DOI: 10.7270/Q2Z89C75
More data for this
Ligand-Target Pair