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2 similar compounds to monomer 50278005

Compile data set for download or QSAR
Wt: 268.3
BDBM50277958
Wt: 269.2
BDBM50278006

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277958,50278006   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50277958
PNG
((R)-5-methyl-3-(4-(pyridin-4-yl)benzyl)oxazolidin-...)
Show SMILES C[C@@H]1CN(Cc2ccc(cc2)-c2ccncc2)C(=O)O1
Show InChI InChI=1S/C16H16N2O2/c1-12-10-18(16(19)20-12)11-13-2-4-14(5-3-13)15-6-8-17-9-7-15/h2-9,12H,10-11H2,1H3/t12-/m1/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/an/a 4.79E+3n/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate


Bioorg Med Chem Lett 19: 2524-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.032
BindingDB Entry DOI: 10.7270/Q2F18ZK7
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50278006
PNG
((R)-5-methyl-3-(4-(pyrimidin-5-yl)benzyl)oxazolidi...)
Show SMILES C[C@@H]1CN(Cc2ccc(cc2)-c2cncnc2)C(=O)O1
Show InChI InChI=1S/C15H15N3O2/c1-11-8-18(15(19)20-11)9-12-2-4-13(5-3-12)14-6-16-10-17-7-14/h2-7,10-11H,8-9H2,1H3/t11-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 4.38E+3n/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate


Bioorg Med Chem Lett 19: 2524-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.032
BindingDB Entry DOI: 10.7270/Q2F18ZK7
More data for this
Ligand-Target Pair