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2 similar compounds to monomer 22911

Compile data set for download or QSAR
Wt: 184.2
BDBM50280119
Wt: 198.2
BDBM50280121

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280119,50280121   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50280121
PNG
(2-[2-(1H-Imidazol-4-yl)-ethyl]-1,1-dimethyl-isothi...)
Show SMILES CN(C)C(=N)SCCc1cnc[nH]1
Show InChI InChI=1S/C8H14N4S/c1-12(2)8(9)13-4-3-7-5-10-6-11-7/h5-6,9H,3-4H2,1-2H3,(H,10,11)
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
500n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The compound was evaluated for antagonistic effect on release of [3H]-histamine from rat brain cortical slices with L-[3H]-histidine at 0.3 microM


Bioorg Med Chem Lett 2: 1231-1234 (1992)


Article DOI: 10.1016/S0960-894X(00)80219-X
BindingDB Entry DOI: 10.7270/Q2J38SGF
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50280119
PNG
(2-[2-(1H-Imidazol-4-yl)-ethyl]-1-methyl-isothioure...)
Show SMILES CN=C(N)SCCc1cnc[nH]1
Show InChI InChI=1S/C7H12N4S/c1-9-7(8)12-3-2-6-4-10-5-11-6/h4-5H,2-3H2,1H3,(H2,8,9)(H,10,11)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/an/an/a 15n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The compound was evaluated for agonistic effect on release of [3H]-histamine from rat brain cortical slices with L-[3H]-histidine at 0.3 microM


Bioorg Med Chem Lett 2: 1231-1234 (1992)


Article DOI: 10.1016/S0960-894X(00)80219-X
BindingDB Entry DOI: 10.7270/Q2J38SGF
More data for this
Ligand-Target Pair