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1 similar compounds to monomer 50280419

Compile data set for download or QSAR
Wt: 406.5
BDBM50280416

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280416   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50280416
PNG
(2-[3-(1-Methyl-1H-imidazol-2-ylsulfanyl)-propylsul...)
Show SMILES Cn1ccnc1SCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H22N4S2/c1-26-14-13-23-22(26)28-16-8-15-27-21-24-19(17-9-4-2-5-10-17)20(25-21)18-11-6-3-7-12-18/h2-7,9-14H,8,15-16H2,1H3,(H,24,25)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 14n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liver


Bioorg Med Chem Lett 2: 375-380 (1992)


Article DOI: 10.1016/S0960-894X(00)80149-3
BindingDB Entry DOI: 10.7270/Q2MP535G
More data for this
Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)
BDBM50280416
PNG
(2-[3-(1-Methyl-1H-imidazol-2-ylsulfanyl)-propylsul...)
Show SMILES Cn1ccnc1SCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H22N4S2/c1-26-14-13-23-22(26)28-16-8-15-27-21-24-19(17-9-4-2-5-10-17)20(25-21)18-11-6-3-7-12-18/h2-7,9-14H,8,15-16H2,1H3,(H,24,25)
Reactome pathway
KEGG

UniProtKB/TrEMBL

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 970n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from cholesterol fed rabbit liver


Bioorg Med Chem Lett 2: 375-380 (1992)


Article DOI: 10.1016/S0960-894X(00)80149-3
BindingDB Entry DOI: 10.7270/Q2MP535G
More data for this
Ligand-Target Pair