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28 similar compounds to monomer 50288566

Compile data set for download or QSAR
Wt: 477.6
BDBM50291012
Wt: 477.6
BDBM50291013
Wt: 477.5
BDBM50291015
Wt: 488.6
BDBM50288560
Wt: 507.6
BDBM50288561
Wt: 589.5
BDBM50288562
Wt: 513.6
BDBM50288563
Wt: 531.6
BDBM50288564
Wt: 498.0
BDBM50288569
Wt: 532.5
BDBM50288573
Wt: 506.6
BDBM50288574
Wt: 513.6
BDBM50288575
Wt: 600.4
BDBM50287396
Wt: 463.6
BDBM50287397
Wt: 504.4
BDBM50287398
Displayed 1 to 15 (of 28 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50291012,50291013,50291015,50288560,50288561,50288562,50288563,50288564,50288569,50288573,50288574,50288575,50287396,50287397,50287398   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Substance-P receptor


(Homo sapiens (Human))
BDBM50288560
PNG
(4-{(2R,4S)-1-(3,5-Dimethyl-benzoyl)-4-[(quinolin-4...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccc(cc1)C#N)NCc1ccnc2ccccc12
Show InChI InChI=1S/C32H32N4O/c1-22-15-23(2)17-27(16-22)32(37)36-14-12-28(19-29(36)18-24-7-9-25(20-33)10-8-24)35-21-26-11-13-34-31-6-4-3-5-30(26)31/h3-11,13,15-17,28-29,35H,12,14,18-19,21H2,1-2H3/t28-,29+/m0/s1
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n/an/a 21n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against NK1 receptor by displacement of [3H]-SP from bovine retina membranes


Bioorg Med Chem Lett 6: 3029-3034 (1996)


Article DOI: 10.1016/S0960-894X(96)00563-X
BindingDB Entry DOI: 10.7270/Q22N5283
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50287397
PNG
(CGP-49823 | CHEMBL290364 | {(2R,4S)-2-Benzyl-4-[(q...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccccc1)NCc1ccnc2ccccc12
Show InChI InChI=1S/C31H33N3O/c1-22-16-23(2)18-26(17-22)31(35)34-15-13-27(20-28(34)19-24-8-4-3-5-9-24)33-21-25-12-14-32-30-11-7-6-10-29(25)30/h3-12,14,16-18,27-28,33H,13,15,19-21H2,1-2H3/t27-,28+/m0/s1
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n/an/a 55n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SP radioligand binding to NK1 receptor from bovine retina


Bioorg Med Chem Lett 6: 1623-1628 (1996)


Article DOI: 10.1016/0960-894X(96)00287-9
BindingDB Entry DOI: 10.7270/Q2N016GN
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50288562
PNG
((3,5-Dimethyl-phenyl)-{(2R,4S)-2-(4-iodo-benzyl)-4...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccc(I)cc1)NCc1ccnc2ccccc12
Show InChI InChI=1S/C31H32IN3O/c1-21-15-22(2)17-25(16-21)31(36)35-14-12-27(19-28(35)18-23-7-9-26(32)10-8-23)34-20-24-11-13-33-30-6-4-3-5-29(24)30/h3-11,13,15-17,27-28,34H,12,14,18-20H2,1-2H3/t27-,28+/m0/s1
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n/an/a 7n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against NK1 receptor by displacement of [3H]-SP from bovine retina membranes


Bioorg Med Chem Lett 6: 3029-3034 (1996)


Article DOI: 10.1016/S0960-894X(96)00563-X
BindingDB Entry DOI: 10.7270/Q22N5283
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50288563
PNG
((3,5-Dimethyl-phenyl)-{(2R,4S)-2-naphthalen-2-ylme...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccc2ccccc2c1)NCc1ccnc2ccccc12
Show InChI InChI=1S/C35H35N3O/c1-24-17-25(2)19-30(18-24)35(39)38-16-14-31(37-23-29-13-15-36-34-10-6-5-9-33(29)34)22-32(38)21-26-11-12-27-7-3-4-8-28(27)20-26/h3-13,15,17-20,31-32,37H,14,16,21-23H2,1-2H3/t31-,32+/m0/s1
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n/an/a 14n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against NK1 receptor by displacement of [3H]-SP from bovine retina membranes


Bioorg Med Chem Lett 6: 3029-3034 (1996)


Article DOI: 10.1016/S0960-894X(96)00563-X
BindingDB Entry DOI: 10.7270/Q22N5283
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50288564
PNG
((3,5-Dimethyl-phenyl)-[(2R,4S)-4-[(quinolin-4-ylme...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccc(cc1)C(F)(F)F)NCc1ccnc2ccccc12
Show InChI InChI=1S/C32H32F3N3O/c1-21-15-22(2)17-25(16-21)31(39)38-14-12-27(37-20-24-11-13-36-30-6-4-3-5-29(24)30)19-28(38)18-23-7-9-26(10-8-23)32(33,34)35/h3-11,13,15-17,27-28,37H,12,14,18-20H2,1-2H3/t27-,28+/m0/s1
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n/an/a 11n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against NK1 receptor by displacement of [3H]-SP from bovine retina membranes


Bioorg Med Chem Lett 6: 3029-3034 (1996)


Article DOI: 10.1016/S0960-894X(96)00563-X
BindingDB Entry DOI: 10.7270/Q22N5283
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50287397
PNG
(CGP-49823 | CHEMBL290364 | {(2R,4S)-2-Benzyl-4-[(q...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccccc1)NCc1ccnc2ccccc12
Show InChI InChI=1S/C31H33N3O/c1-22-16-23(2)18-26(17-22)31(35)34-15-13-27(20-28(34)19-24-8-4-3-5-9-24)33-21-25-12-14-32-30-11-7-6-10-29(25)30/h3-12,14,16-18,27-28,33H,13,15,19-21H2,1-2H3/t27-,28+/m0/s1
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n/an/a 12n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against NK1 receptor by displacement of [3H]-SP from bovine retina membranes


Bioorg Med Chem Lett 6: 3029-3034 (1996)


Article DOI: 10.1016/S0960-894X(96)00563-X
BindingDB Entry DOI: 10.7270/Q22N5283
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50288569
PNG
(CHEMBL102569 | {(2R,4S)-2-(4-Chloro-benzyl)-4-[(qu...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccc(Cl)cc1)NCc1ccnc2ccccc12
Show InChI InChI=1S/C31H32ClN3O/c1-21-15-22(2)17-25(16-21)31(36)35-14-12-27(19-28(35)18-23-7-9-26(32)10-8-23)34-20-24-11-13-33-30-6-4-3-5-29(24)30/h3-11,13,15-17,27-28,34H,12,14,18-20H2,1-2H3/t27-,28+/m0/s1
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n/an/a 13n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against NK1 receptor by displacement of [3H]-SP from bovine retina membranes


Bioorg Med Chem Lett 6: 3029-3034 (1996)


Article DOI: 10.1016/S0960-894X(96)00563-X
BindingDB Entry DOI: 10.7270/Q22N5283
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50288573
PNG
(CHEMBL105800 | {(2R,4S)-2-(2,4-Dichloro-benzyl)-4-...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccc(Cl)cc1Cl)NCc1ccnc2ccccc12
Show InChI InChI=1S/C31H31Cl2N3O/c1-20-13-21(2)15-24(14-20)31(37)36-12-10-26(18-27(36)16-22-7-8-25(32)17-29(22)33)35-19-23-9-11-34-30-6-4-3-5-28(23)30/h3-9,11,13-15,17,26-27,35H,10,12,16,18-19H2,1-2H3/t26-,27+/m0/s1
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n/an/a 600n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against NK1 receptor by displacement of [3H]-SP from bovine retina membranes


Bioorg Med Chem Lett 6: 3029-3034 (1996)


Article DOI: 10.1016/S0960-894X(96)00563-X
BindingDB Entry DOI: 10.7270/Q22N5283
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50288574
PNG
(4-{(2R,4S)-1-(3,5-Dimethyl-benzoyl)-4-[(quinolin-4...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccc(cc1)C(N)=O)NCc1ccnc2ccccc12
Show InChI InChI=1S/C32H34N4O2/c1-21-15-22(2)17-26(16-21)32(38)36-14-12-27(19-28(36)18-23-7-9-24(10-8-23)31(33)37)35-20-25-11-13-34-30-6-4-3-5-29(25)30/h3-11,13,15-17,27-28,35H,12,14,18-20H2,1-2H3,(H2,33,37)/t27-,28+/m0/s1
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n/an/a 100n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against NK1 receptor by displacement of [3H]-SP from bovine retina membranes


Bioorg Med Chem Lett 6: 3029-3034 (1996)


Article DOI: 10.1016/S0960-894X(96)00563-X
BindingDB Entry DOI: 10.7270/Q22N5283
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50288575
PNG
((3,5-Dimethyl-phenyl)-{(2R,4S)-2-naphthalen-1-ylme...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1cccc2ccccc12)NCc1ccnc2ccccc12
Show InChI InChI=1S/C35H35N3O/c1-24-18-25(2)20-29(19-24)35(39)38-17-15-30(37-23-28-14-16-36-34-13-6-5-12-33(28)34)22-31(38)21-27-10-7-9-26-8-3-4-11-32(26)27/h3-14,16,18-20,30-31,37H,15,17,21-23H2,1-2H3/t30-,31+/m0/s1
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n/an/a 29n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against NK1 receptor by displacement of [3H]-SP from bovine retina membranes


Bioorg Med Chem Lett 6: 3029-3034 (1996)


Article DOI: 10.1016/S0960-894X(96)00563-X
BindingDB Entry DOI: 10.7270/Q22N5283
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50287396
PNG
(CHEMBL40189 | N-[(2R,4S)-2-Benzyl-1-(3,5-dichloro-...)
Show SMILES FC(F)(F)C(=O)N(Cc1ccnc2ccccc12)[C@H]1CCN([C@H](Cc2ccccc2)C1)C(=O)c1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C31H26Cl2F3N3O2/c32-23-15-22(16-24(33)17-23)29(40)38-13-11-25(18-26(38)14-20-6-2-1-3-7-20)39(30(41)31(34,35)36)19-21-10-12-37-28-9-5-4-8-27(21)28/h1-10,12,15-17,25-26H,11,13-14,18-19H2/t25-,26+/m0/s1
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n/an/a 600n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SP radioligand binding to NK1 receptor from bovine retina


Bioorg Med Chem Lett 6: 1623-1628 (1996)


Article DOI: 10.1016/0960-894X(96)00287-9
BindingDB Entry DOI: 10.7270/Q2N016GN
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50287398
PNG
(CHEMBL43744 | {(2R,4S)-2-Benzyl-4-[(quinolin-4-ylm...)
Show SMILES Clc1cc(Cl)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccccc1)NCc1ccnc2ccccc12
Show InChI InChI=1S/C29H27Cl2N3O/c30-23-15-22(16-24(31)17-23)29(35)34-13-11-25(18-26(34)14-20-6-2-1-3-7-20)33-19-21-10-12-32-28-9-5-4-8-27(21)28/h1-10,12,15-17,25-26,33H,11,13-14,18-19H2/t25-,26+/m0/s1
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n/an/a 26n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SP radioligand binding to NK1 receptor from bovine retina


Bioorg Med Chem Lett 6: 1623-1628 (1996)


Article DOI: 10.1016/0960-894X(96)00287-9
BindingDB Entry DOI: 10.7270/Q2N016GN
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50287397
PNG
(CGP-49823 | CHEMBL290364 | {(2R,4S)-2-Benzyl-4-[(q...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccccc1)NCc1ccnc2ccccc12
Show InChI InChI=1S/C31H33N3O/c1-22-16-23(2)18-26(17-22)31(35)34-15-13-27(20-28(34)19-24-8-4-3-5-9-24)33-21-25-12-14-32-30-11-7-6-10-29(25)30/h3-12,14,16-18,27-28,33H,13,15,19-21H2,1-2H3/t27-,28+/m0/s1
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n/an/a 13n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SP radioligand binding to NK1 receptor from bovine retina


Bioorg Med Chem Lett 6: 1623-1628 (1996)


Article DOI: 10.1016/0960-894X(96)00287-9
BindingDB Entry DOI: 10.7270/Q2N016GN
More data for this
Ligand-Target Pair
Neuromedin-K receptor


(Homo sapiens (Human))
BDBM50287397
PNG
(CGP-49823 | CHEMBL290364 | {(2R,4S)-2-Benzyl-4-[(q...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccccc1)NCc1ccnc2ccccc12
Show InChI InChI=1S/C31H33N3O/c1-22-16-23(2)18-26(17-22)31(35)34-15-13-27(20-28(34)19-24-8-4-3-5-9-24)33-21-25-12-14-32-30-11-7-6-10-29(25)30/h3-12,14,16-18,27-28,33H,13,15,19-21H2,1-2H3/t27-,28+/m0/s1
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n/an/a 2.65E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of [125I]-Eledoisin radioligand binding to NK3 receptor from gerbil cortex


Bioorg Med Chem Lett 6: 1623-1628 (1996)


Article DOI: 10.1016/0960-894X(96)00287-9
BindingDB Entry DOI: 10.7270/Q2N016GN
More data for this
Ligand-Target Pair
Neurokinin 2 receptor


(Bos taurus)
BDBM50287397
PNG
(CGP-49823 | CHEMBL290364 | {(2R,4S)-2-Benzyl-4-[(q...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccccc1)NCc1ccnc2ccccc12
Show InChI InChI=1S/C31H33N3O/c1-22-16-23(2)18-26(17-22)31(35)34-15-13-27(20-28(34)19-24-8-4-3-5-9-24)33-21-25-12-14-32-30-11-7-6-10-29(25)30/h3-12,14,16-18,27-28,33H,13,15,19-21H2,1-2H3/t27-,28+/m0/s1
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n/an/a 2.79E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of [125I]-NKA radioligand binding to NK2 receptor from bovine bladder


Bioorg Med Chem Lett 6: 1623-1628 (1996)


Article DOI: 10.1016/0960-894X(96)00287-9
BindingDB Entry DOI: 10.7270/Q2N016GN
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50291012
PNG
((3,5-Dimethyl-phenyl)-{2-((R)-1-phenyl-ethyl)-4-[(...)
Show SMILES C[C@@H](C1CC(CCN1C(=O)c1cc(C)cc(C)c1)NCc1ccnc2ccccc12)c1ccccc1
Show InChI InChI=1S/C32H35N3O/c1-22-17-23(2)19-27(18-22)32(36)35-16-14-28(20-31(35)24(3)25-9-5-4-6-10-25)34-21-26-13-15-33-30-12-8-7-11-29(26)30/h4-13,15,17-19,24,28,31,34H,14,16,20-21H2,1-3H3/t24-,28?,31?/m1/s1
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n/an/a 30n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory potency against Neurokinin 1 NK1 receptor


Bioorg Med Chem Lett 7: 347-350 (1997)


Article DOI: 10.1016/S0960-894X(96)00623-3
BindingDB Entry DOI: 10.7270/Q2PK0G48
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50291013
PNG
((3,5-Dimethyl-phenyl)-{2-((S)-1-phenyl-ethyl)-4-[(...)
Show SMILES C[C@H](C1CC(CCN1C(=O)c1cc(C)cc(C)c1)NCc1ccnc2ccccc12)c1ccccc1
Show InChI InChI=1S/C32H35N3O/c1-22-17-23(2)19-27(18-22)32(36)35-16-14-28(20-31(35)24(3)25-9-5-4-6-10-25)34-21-26-13-15-33-30-12-8-7-11-29(26)30/h4-13,15,17-19,24,28,31,34H,14,16,20-21H2,1-3H3/t24-,28?,31?/m0/s1
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n/an/a 2.30E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory potency against Neurokinin 1 NK1 receptor


Bioorg Med Chem Lett 7: 347-350 (1997)


Article DOI: 10.1016/S0960-894X(96)00623-3
BindingDB Entry DOI: 10.7270/Q2PK0G48
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50287397
PNG
(CGP-49823 | CHEMBL290364 | {(2R,4S)-2-Benzyl-4-[(q...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccccc1)NCc1ccnc2ccccc12
Show InChI InChI=1S/C31H33N3O/c1-22-16-23(2)18-26(17-22)31(35)34-15-13-27(20-28(34)19-24-8-4-3-5-9-24)33-21-25-12-14-32-30-11-7-6-10-29(25)30/h3-12,14,16-18,27-28,33H,13,15,19-21H2,1-2H3/t27-,28+/m0/s1
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n/an/a 12n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory potency against Neurokinin 1 NK1 receptor


Bioorg Med Chem Lett 7: 347-350 (1997)


Article DOI: 10.1016/S0960-894X(96)00623-3
BindingDB Entry DOI: 10.7270/Q2PK0G48
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50287397
PNG
(CGP-49823 | CHEMBL290364 | {(2R,4S)-2-Benzyl-4-[(q...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccccc1)NCc1ccnc2ccccc12
Show InChI InChI=1S/C31H33N3O/c1-22-16-23(2)18-26(17-22)31(35)34-15-13-27(20-28(34)19-24-8-4-3-5-9-24)33-21-25-12-14-32-30-11-7-6-10-29(25)30/h3-12,14,16-18,27-28,33H,13,15,19-21H2,1-2H3/t27-,28+/m0/s1
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n/an/a 12n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the binding affinity of the compound against neurokinin NK1 receptor


Bioorg Med Chem Lett 7: 351-354 (1997)


Article DOI: 10.1016/S0960-894X(96)00624-5
BindingDB Entry DOI: 10.7270/Q2JS9QFF
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50291015
PNG
(CHEMBL116535 | Quinoline-4-carboxylic acid [(R)-2-...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccccc1)NC(=O)c1ccnc2ccccc12
Show InChI InChI=1S/C31H31N3O2/c1-21-16-22(2)18-24(17-21)31(36)34-15-13-25(20-26(34)19-23-8-4-3-5-9-23)33-30(35)28-12-14-32-29-11-7-6-10-27(28)29/h3-12,14,16-18,25-26H,13,15,19-20H2,1-2H3,(H,33,35)/t25-,26+/m0/s1
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n/an/a 15n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the binding affinity of the compound against neurokinin NK1 receptor


Bioorg Med Chem Lett 7: 351-354 (1997)


Article DOI: 10.1016/S0960-894X(96)00624-5
BindingDB Entry DOI: 10.7270/Q2JS9QFF
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))
BDBM50288561
PNG
(4-{(2R,4S)-1-(3,5-Dimethyl-benzoyl)-4-[(quinolin-4...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccc(cc1)C(O)=O)NCc1ccnc2ccccc12
Show InChI InChI=1S/C32H33N3O3/c1-21-15-22(2)17-26(16-21)31(36)35-14-12-27(19-28(35)18-23-7-9-24(10-8-23)32(37)38)34-20-25-11-13-33-30-6-4-3-5-29(25)30/h3-11,13,15-17,27-28,34H,12,14,18-20H2,1-2H3,(H,37,38)/t27-,28+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against NK1 receptor by displacement of [3H]-SP from bovine retina membranes


Bioorg Med Chem Lett 6: 3029-3034 (1996)


Article DOI: 10.1016/S0960-894X(96)00563-X
BindingDB Entry DOI: 10.7270/Q22N5283
More data for this
Ligand-Target Pair