BindingDB logo
myBDB logout

15 similar compounds to monomer 50296490

Wt: 338.3
BDBM50296486
Wt: 320.3
BDBM50296487
Wt: 320.3
BDBM50296489
Wt: 388.3
BDBM50296491
Wt: 334.3
BDBM50296492
Wt: 354.7
BDBM50296493
Wt: 320.3
BDBM50296494
Wt: 320.3
BDBM50296495
Wt: 332.3
BDBM50296504
Wt: 372.2
BDBM50296507
Wt: 354.2
BDBM50296508
Wt: 336.3
BDBM50296509
Wt: 336.3
BDBM50296510
Wt: 336.3
BDBM50296511
Wt: 318.3
BDBM50296512

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 73 hits for monomerid = 50296486,50296487,50296489,50296491,50296492,50296493,50296494,50296495,50296504,50296507,50296508,50296509,50296510,50296511,50296512   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM50296486
PNG
((11R,12R)-12-azaniumyl-4-fluoro-11-(2,4,5-trifluor...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(F)cc21
Show InChI InChI=1S/C16H12F4N4/c17-9-3-11(19)10(18)1-7(9)8-2-16-23-13-5-22-15(20)4-14(13)24(16)6-12(8)21/h1,3-5,8,12H,2,6,21H2/p+2/t8-,12+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.10E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human ERG


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM50296487
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1ncccc21
Show InChI InChI=1S/C16H13F3N4/c17-10-6-12(19)11(18)4-8(10)9-5-15-22-16-14(2-1-3-21-16)23(15)7-13(9)20/h1-4,6,9,13H,5,7,20H2/p+2/t9-,13+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.00E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human ERG


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296489
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnccc21
Show InChI InChI=1S/C16H13F3N4/c17-10-5-12(19)11(18)3-8(10)9-4-16-22-14-6-21-2-1-15(14)23(16)7-13(9)20/h1-3,5-6,9,13H,4,7,20H2/p+2/t9-,13+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human endogenous DPP4 in presence of 50% human serum


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296491
PNG
((11R,12R)-12-azaniumyl-4-(trifluoromethyl)-11-(2,4...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(cc21)C(F)(F)F
Show InChI InChI=1S/C17H12F6N4/c18-9-3-11(20)10(19)1-7(9)8-2-16-26-13-5-25-15(17(21,22)23)4-14(13)27(16)6-12(8)24/h1,3-5,8,12H,2,6,24H2/p+2/t8-,12+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 32n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human endogenous DPP4 in presence of 50% human serum


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296486
PNG
((11R,12R)-12-azaniumyl-4-fluoro-11-(2,4,5-trifluor...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(F)cc21
Show InChI InChI=1S/C16H12F4N4/c17-9-3-11(19)10(18)1-7(9)8-2-16-23-13-5-22-15(20)4-14(13)24(16)6-12(8)21/h1,3-5,8,12H,2,6,21H2/p+2/t8-,12+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 23n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human endogenous DPP4 in presence of 50% human serum


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296487
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1ncccc21
Show InChI InChI=1S/C16H13F3N4/c17-10-6-12(19)11(18)4-8(10)9-5-15-22-16-14(2-1-3-21-16)23(15)7-13(9)20/h1-4,6,9,13H,5,7,20H2/p+2/t9-,13+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human endogenous DPP4 in presence of 50% human serum


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Cytochrome P450 2D6 (2D6)


(Homo sapiens (Human))
BDBM50296489
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnccc21
Show InChI InChI=1S/C16H13F3N4/c17-10-5-12(19)11(18)3-8(10)9-4-16-22-14-6-21-2-1-15(14)23(16)7-13(9)20/h1-3,5-6,9,13H,4,7,20H2/p+2/t9-,13+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of CYP2D6


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Cytochrome P450 2D6 (2D6)


(Homo sapiens (Human))
BDBM50296491
PNG
((11R,12R)-12-azaniumyl-4-(trifluoromethyl)-11-(2,4...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(cc21)C(F)(F)F
Show InChI InChI=1S/C17H12F6N4/c18-9-3-11(20)10(19)1-7(9)8-2-16-26-13-5-25-15(17(21,22)23)4-14(13)27(16)6-12(8)24/h1,3-5,8,12H,2,6,24H2/p+2/t8-,12+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of CYP2D6


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Cytochrome P450 2D6 (2D6)


(Homo sapiens (Human))
BDBM50296487
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1ncccc21
Show InChI InChI=1S/C16H13F3N4/c17-10-6-12(19)11(18)4-8(10)9-5-15-22-16-14(2-1-3-21-16)23(15)7-13(9)20/h1-4,6,9,13H,5,7,20H2/p+2/t9-,13+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.20E+3n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of CYP2D6


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Cytochrome P450 2D6 (2D6)


(Homo sapiens (Human))
BDBM50296486
PNG
((11R,12R)-12-azaniumyl-4-fluoro-11-(2,4,5-trifluor...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(F)cc21
Show InChI InChI=1S/C16H12F4N4/c17-9-3-11(19)10(18)1-7(9)8-2-16-23-13-5-22-15(20)4-14(13)24(16)6-12(8)21/h1,3-5,8,12H,2,6,21H2/p+2/t8-,12+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of CYP2D6


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296487
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1ncccc21
Show InChI InChI=1S/C16H13F3N4/c17-10-6-12(19)11(18)4-8(10)9-5-15-22-16-14(2-1-3-21-16)23(15)7-13(9)20/h1-4,6,9,13H,5,7,20H2/p+2/t9-,13+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296491
PNG
((11R,12R)-12-azaniumyl-4-(trifluoromethyl)-11-(2,4...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(cc21)C(F)(F)F
Show InChI InChI=1S/C17H12F6N4/c18-9-3-11(20)10(19)1-7(9)8-2-16-26-13-5-25-15(17(21,22)23)4-14(13)27(16)6-12(8)24/h1,3-5,8,12H,2,6,24H2/p+2/t8-,12+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 11n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296492
PNG
((11R,12R)-12-azaniumyl-4-methyl-11-(2,4,5-trifluor...)
Show SMILES Cc1cc2[n+]3C[C@H]([NH3+])[C@H](Cc3[nH]c2cn1)c1cc(F)c(F)cc1F
Show InChI InChI=1S/C17H15F3N4/c1-8-2-16-15(6-22-8)23-17-4-10(14(21)7-24(16)17)9-3-12(19)13(20)5-11(9)18/h2-3,5-6,10,14H,4,7,21H2,1H3/p+2/t10-,14+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 23n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296493
PNG
((11R,12R)-12-azaniumyl-4-chloro-11-(2,4,5-trifluor...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(Cl)cc21
Show InChI InChI=1S/C16H12ClF3N4/c17-15-4-14-13(5-22-15)23-16-2-8(12(21)6-24(14)16)7-1-10(19)11(20)3-9(7)18/h1,3-5,8,12H,2,6,21H2/p+2/t8-,12+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296486
PNG
((11R,12R)-12-azaniumyl-4-fluoro-11-(2,4,5-trifluor...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(F)cc21
Show InChI InChI=1S/C16H12F4N4/c17-9-3-11(19)10(18)1-7(9)8-2-16-23-13-5-22-15(20)4-14(13)24(16)6-12(8)21/h1,3-5,8,12H,2,6,21H2/p+2/t8-,12+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296489
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnccc21
Show InChI InChI=1S/C16H13F3N4/c17-10-5-12(19)11(18)3-8(10)9-4-16-22-14-6-21-2-1-15(14)23(16)7-13(9)20/h1-3,5-6,9,13H,4,7,20H2/p+2/t9-,13+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.70n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296494
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1ccncc21
Show InChI InChI=1S/C16H13F3N4/c17-10-5-12(19)11(18)3-8(10)9-4-16-22-14-1-2-21-6-15(14)23(16)7-13(9)20/h1-3,5-6,9,13H,4,7,20H2/p+2/t9-,13+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 51n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296495
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cccnc21
Show InChI InChI=1S/C16H13F3N4/c17-10-6-12(19)11(18)4-8(10)9-5-15-22-14-2-1-3-21-16(14)23(15)7-13(9)20/h1-4,6,9,13H,5,7,20H2/p+2/t9-,13+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 329n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296504
PNG
(CHEMBL562953 | Trifluoro-acetate(2R,3R)-7-methyl-3...)
Show SMILES Cc1ccc2n3C[C@H]([NH3+])[C@H](Cc3nc2c1)c1cc(F)c(F)cc1F
Show InChI InChI=1S/C18H16F3N3/c1-9-2-3-17-16(4-9)23-18-6-11(15(22)8-24(17)18)10-5-13(20)14(21)7-12(10)19/h2-5,7,11,15H,6,8,22H2,1H3/p+1/t11-,15+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296507
PNG
(CHEMBL562530 | Trifluoro-acetate(2R,3R)-6,7,8-trif...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1c(F)c(F)c(F)cc21
Show InChI InChI=1S/C17H11F6N3/c18-8-3-10(20)9(19)1-6(8)7-2-14-25-17-13(26(14)5-12(7)24)4-11(21)15(22)16(17)23/h1,3-4,7,12H,2,5,24H2/p+1/t7-,12+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296508
PNG
(CHEMBL558253 | Trifluoro-acetate(2R,3R)-6,8-difluo...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1c(F)cc(F)cc21
Show InChI InChI=1S/C17H12F5N3/c18-7-1-13(22)17-15(2-7)25-6-14(23)9(4-16(25)24-17)8-3-11(20)12(21)5-10(8)19/h1-3,5,9,14H,4,6,23H2/p+1/t9-,14+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 47n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296509
PNG
(CHEMBL560669 | Trifluoro-acetate(2R,3R)-8-fluoro-3...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1ccc(F)cc21
Show InChI InChI=1S/C17H13F4N3/c18-8-1-2-15-16(3-8)24-7-14(22)10(5-17(24)23-15)9-4-12(20)13(21)6-11(9)19/h1-4,6,10,14H,5,7,22H2/p+1/t10-,14+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 17n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296510
PNG
(CHEMBL552071 | Trifluoro-acetate(2R,3R)-7-fluoro-3...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1cc(F)ccc21
Show InChI InChI=1S/C17H13F4N3/c18-8-1-2-16-15(3-8)23-17-5-10(14(22)7-24(16)17)9-4-12(20)13(21)6-11(9)19/h1-4,6,10,14H,5,7,22H2/p+1/t10-,14+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 77n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296511
PNG
(CHEMBL537962 | Trifluoro-acetate(2R,3R)-6-fluoro-3...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1c(F)cccc21
Show InChI InChI=1S/C17H13F4N3/c18-10-2-1-3-15-17(10)23-16-5-9(14(22)7-24(15)16)8-4-12(20)13(21)6-11(8)19/h1-4,6,9,14H,5,7,22H2/p+1/t9-,14+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50296512
PNG
(CHEMBL549913 | Trifluoro-acetate(2R,3R)-3-(2,4,5-t...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1ccccc21
Show InChI InChI=1S/C17H14F3N3/c18-11-7-13(20)12(19)5-9(11)10-6-17-22-15-3-1-2-4-16(15)23(17)8-14(10)21/h1-5,7,10,14H,6,8,21H2/p+1/t10-,14+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 68n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296491
PNG
((11R,12R)-12-azaniumyl-4-(trifluoromethyl)-11-(2,4...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(cc21)C(F)(F)F
Show InChI InChI=1S/C17H12F6N4/c18-9-3-11(20)10(19)1-7(9)8-2-16-26-13-5-25-15(17(21,22)23)4-14(13)27(16)6-12(8)24/h1,3-5,8,12H,2,6,24H2/p+2/t8-,12+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296487
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1ncccc21
Show InChI InChI=1S/C16H13F3N4/c17-10-6-12(19)11(18)4-8(10)9-5-15-22-16-14(2-1-3-21-16)23(15)7-13(9)20/h1-4,6,9,13H,5,7,20H2/p+2/t9-,13+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296493
PNG
((11R,12R)-12-azaniumyl-4-chloro-11-(2,4,5-trifluor...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(Cl)cc21
Show InChI InChI=1S/C16H12ClF3N4/c17-15-4-14-13(5-22-15)23-16-2-8(12(21)6-24(14)16)7-1-10(19)11(20)3-9(7)18/h1,3-5,8,12H,2,6,21H2/p+2/t8-,12+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.60E+3n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296492
PNG
((11R,12R)-12-azaniumyl-4-methyl-11-(2,4,5-trifluor...)
Show SMILES Cc1cc2[n+]3C[C@H]([NH3+])[C@H](Cc3[nH]c2cn1)c1cc(F)c(F)cc1F
Show InChI InChI=1S/C17H15F3N4/c1-8-2-16-15(6-22-8)23-17-4-10(14(21)7-24(16)17)9-3-12(19)13(20)5-11(9)18/h2-3,5-6,10,14H,4,7,21H2,1H3/p+2/t10-,14+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.90E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296486
PNG
((11R,12R)-12-azaniumyl-4-fluoro-11-(2,4,5-trifluor...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(F)cc21
Show InChI InChI=1S/C16H12F4N4/c17-9-3-11(19)10(18)1-7(9)8-2-16-23-13-5-22-15(20)4-14(13)24(16)6-12(8)21/h1,3-5,8,12H,2,6,21H2/p+2/t8-,12+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296489
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnccc21
Show InChI InChI=1S/C16H13F3N4/c17-10-5-12(19)11(18)3-8(10)9-4-16-22-14-6-21-2-1-15(14)23(16)7-13(9)20/h1-3,5-6,9,13H,4,7,20H2/p+2/t9-,13+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296494
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1ccncc21
Show InChI InChI=1S/C16H13F3N4/c17-10-5-12(19)11(18)3-8(10)9-4-16-22-14-1-2-21-6-15(14)23(16)7-13(9)20/h1-3,5-6,9,13H,4,7,20H2/p+2/t9-,13+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296495
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cccnc21
Show InChI InChI=1S/C16H13F3N4/c17-10-6-12(19)11(18)4-8(10)9-5-15-22-14-2-1-3-21-16(14)23(15)7-13(9)20/h1-4,6,9,13H,5,7,20H2/p+2/t9-,13+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296504
PNG
(CHEMBL562953 | Trifluoro-acetate(2R,3R)-7-methyl-3...)
Show SMILES Cc1ccc2n3C[C@H]([NH3+])[C@H](Cc3nc2c1)c1cc(F)c(F)cc1F
Show InChI InChI=1S/C18H16F3N3/c1-9-2-3-17-16(4-9)23-18-6-11(15(22)8-24(17)18)10-5-13(20)14(21)7-12(10)19/h2-5,7,11,15H,6,8,22H2,1H3/p+1/t11-,15+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.30E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296507
PNG
(CHEMBL562530 | Trifluoro-acetate(2R,3R)-6,7,8-trif...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1c(F)c(F)c(F)cc21
Show InChI InChI=1S/C17H11F6N3/c18-8-3-10(20)9(19)1-6(8)7-2-14-25-17-13(26(14)5-12(7)24)4-11(21)15(22)16(17)23/h1,3-4,7,12H,2,5,24H2/p+1/t7-,12+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.50E+3n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296508
PNG
(CHEMBL558253 | Trifluoro-acetate(2R,3R)-6,8-difluo...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1c(F)cc(F)cc21
Show InChI InChI=1S/C17H12F5N3/c18-7-1-13(22)17-15(2-7)25-6-14(23)9(4-16(25)24-17)8-3-11(20)12(21)5-10(8)19/h1-3,5,9,14H,4,6,23H2/p+1/t9-,14+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.30E+3n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296509
PNG
(CHEMBL560669 | Trifluoro-acetate(2R,3R)-8-fluoro-3...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1ccc(F)cc21
Show InChI InChI=1S/C17H13F4N3/c18-8-1-2-15-16(3-8)24-7-14(22)10(5-17(24)23-15)9-4-12(20)13(21)6-11(9)19/h1-4,6,10,14H,5,7,22H2/p+1/t10-,14+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296510
PNG
(CHEMBL552071 | Trifluoro-acetate(2R,3R)-7-fluoro-3...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1cc(F)ccc21
Show InChI InChI=1S/C17H13F4N3/c18-8-1-2-16-15(3-8)23-17-5-10(14(22)7-24(16)17)9-4-12(20)13(21)6-11(9)19/h1-4,6,10,14H,5,7,22H2/p+1/t10-,14+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296511
PNG
(CHEMBL537962 | Trifluoro-acetate(2R,3R)-6-fluoro-3...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1c(F)cccc21
Show InChI InChI=1S/C17H13F4N3/c18-10-2-1-3-15-17(10)23-16-5-9(14(22)7-24(15)16)8-4-12(20)13(21)6-11(8)19/h1-4,6,9,14H,5,7,22H2/p+1/t9-,14+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.50E+3n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50296512
PNG
(CHEMBL549913 | Trifluoro-acetate(2R,3R)-3-(2,4,5-t...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1ccccc21
Show InChI InChI=1S/C17H14F3N3/c18-11-7-13(20)12(19)5-9(11)10-6-17-22-15-3-1-2-4-16(15)23(17)8-14(10)21/h1-5,7,10,14H,6,8,21H2/p+1/t10-,14+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.20E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant QPP transfected in insect SF9 cells


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (human))
BDBM50296487
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1ncccc21
Show InChI InChI=1S/C16H13F3N4/c17-10-6-12(19)11(18)4-8(10)9-5-15-22-16-14(2-1-3-21-16)23(15)7-13(9)20/h1-4,6,9,13H,5,7,20H2/p+2/t9-,13+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DPP8 expressed in baculovirus by continuous fluorescent assay


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (human))
BDBM50296491
PNG
((11R,12R)-12-azaniumyl-4-(trifluoromethyl)-11-(2,4...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(cc21)C(F)(F)F
Show InChI InChI=1S/C17H12F6N4/c18-9-3-11(20)10(19)1-7(9)8-2-16-26-13-5-25-15(17(21,22)23)4-14(13)27(16)6-12(8)24/h1,3-5,8,12H,2,6,24H2/p+2/t8-,12+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.10E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DPP8 expressed in baculovirus by continuous fluorescent assay


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (human))
BDBM50296492
PNG
((11R,12R)-12-azaniumyl-4-methyl-11-(2,4,5-trifluor...)
Show SMILES Cc1cc2[n+]3C[C@H]([NH3+])[C@H](Cc3[nH]c2cn1)c1cc(F)c(F)cc1F
Show InChI InChI=1S/C17H15F3N4/c1-8-2-16-15(6-22-8)23-17-4-10(14(21)7-24(16)17)9-3-12(19)13(20)5-11(9)18/h2-3,5-6,10,14H,4,7,21H2,1H3/p+2/t10-,14+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.40E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DPP8 expressed in baculovirus by continuous fluorescent assay


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (human))
BDBM50296493
PNG
((11R,12R)-12-azaniumyl-4-chloro-11-(2,4,5-trifluor...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(Cl)cc21
Show InChI InChI=1S/C16H12ClF3N4/c17-15-4-14-13(5-22-15)23-16-2-8(12(21)6-24(14)16)7-1-10(19)11(20)3-9(7)18/h1,3-5,8,12H,2,6,21H2/p+2/t8-,12+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.20E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DPP8 expressed in baculovirus by continuous fluorescent assay


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (human))
BDBM50296486
PNG
((11R,12R)-12-azaniumyl-4-fluoro-11-(2,4,5-trifluor...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnc(F)cc21
Show InChI InChI=1S/C16H12F4N4/c17-9-3-11(19)10(18)1-7(9)8-2-16-23-13-5-22-15(20)4-14(13)24(16)6-12(8)21/h1,3-5,8,12H,2,6,21H2/p+2/t8-,12+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DPP8 expressed in baculovirus by continuous fluorescent assay


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (human))
BDBM50296489
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cnccc21
Show InChI InChI=1S/C16H13F3N4/c17-10-5-12(19)11(18)3-8(10)9-4-16-22-14-6-21-2-1-15(14)23(16)7-13(9)20/h1-3,5-6,9,13H,4,7,20H2/p+2/t9-,13+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DPP8 expressed in baculovirus by continuous fluorescent assay


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (human))
BDBM50296494
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1ccncc21
Show InChI InChI=1S/C16H13F3N4/c17-10-5-12(19)11(18)3-8(10)9-4-16-22-14-1-2-21-6-15(14)23(16)7-13(9)20/h1-3,5-6,9,13H,4,7,20H2/p+2/t9-,13+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.20E+4n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DPP8 expressed in baculovirus by continuous fluorescent assay


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (human))
BDBM50296495
PNG
((11R,12R)-12-azaniumyl-11-(2,4,5-trifluorophenyl)-...)
Show SMILES [NH3+][C@H]1C[n+]2c(C[C@@H]1c1cc(F)c(F)cc1F)[nH]c1cccnc21
Show InChI InChI=1S/C16H13F3N4/c17-10-6-12(19)11(18)4-8(10)9-5-15-22-14-2-1-3-21-16(14)23(15)7-13(9)20/h1-4,6,9,13H,5,7,20H2/p+2/t9-,13+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DPP8 expressed in baculovirus by continuous fluorescent assay


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (human))
BDBM50296504
PNG
(CHEMBL562953 | Trifluoro-acetate(2R,3R)-7-methyl-3...)
Show SMILES Cc1ccc2n3C[C@H]([NH3+])[C@H](Cc3nc2c1)c1cc(F)c(F)cc1F
Show InChI InChI=1S/C18H16F3N3/c1-9-2-3-17-16(4-9)23-18-6-11(15(22)8-24(17)18)10-5-13(20)14(21)7-12(10)19/h2-5,7,11,15H,6,8,22H2,1H3/p+1/t11-,15+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DPP8 expressed in baculovirus by continuous fluorescent assay


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (human))
BDBM50296507
PNG
(CHEMBL562530 | Trifluoro-acetate(2R,3R)-6,7,8-trif...)
Show SMILES [NH3+][C@H]1Cn2c(C[C@@H]1c1cc(F)c(F)cc1F)nc1c(F)c(F)c(F)cc21
Show InChI InChI=1S/C17H11F6N3/c18-8-3-10(20)9(19)1-6(8)7-2-14-25-17-13(26(14)5-12(7)24)4-11(21)15(22)16(17)23/h1,3-4,7,12H,2,5,24H2/p+1/t7-,12+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck& Co. Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DPP8 expressed in baculovirus by continuous fluorescent assay


Bioorg Med Chem Lett 19: 4097-101 (2009)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 73 total )  |  Next  |  Last  >>